Zobrazeno 1 - 10
of 142
pro vyhledávání: '"P J, Conlon"'
Autor:
Atanu Maiti, Cosmo Z. Buffalo, Saumya Saurabh, Felipe Montecinos-Franjola, Justin S. Hachey, William J. Conlon, Geraldine N. Tran, Bakar Hassan, Kylie J. Walters, Mikhail Drobizhev, W. E. Moerner, Partho Ghosh, Hiroshi Matsuo, Roger Y. Tsien, John Y. Lin, Erik A. Rodriguez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The small Ultra-Red Fluorescent Protein (smURFP) represents a new class of fluorescent protein with exceptional photostability and brightness derived from allophycocyanin in a previous directed evolution. Here, we report the smURFP crystal s
Externí odkaz:
https://doaj.org/article/c7b97c5ea32a4f34823ce6ae4a9c9f7e
Autor:
Laura J. Smyth, Emma H. Dahlström, Anna Syreeni, Katie Kerr, Jill Kilner, Ross Doyle, Eoin Brennan, Viji Nair, Damian Fermin, Robert G. Nelson, Helen C. Looker, Christopher Wooster, Darrell Andrews, Kerry Anderson, Gareth J. McKay, Joanne B. Cole, Rany M. Salem, Peter J. Conlon, Matthias Kretzler, Joel N. Hirschhorn, Denise Sadlier, Catherine Godson, Jose C. Florez, GENIE consortium, Carol Forsblom, Alexander P. Maxwell, Per-Henrik Groop, Niina Sandholm, Amy Jayne McKnight
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Approximately 40 percent of people with type 1 diabetes develop kidney disease, but the risk factors are not well understood. Here, the authors identify DNA methylation signatures associated with diabetic kidney disease, of which 21 biomarkers predic
Externí odkaz:
https://doaj.org/article/777a9666411244d6bce4bb7f84d0b5c3
Publikováno v:
Skin Health and Disease, Vol 2, Iss 1, Pp n/a-n/a (2022)
Abstract Background Merkel cell carcinoma (MCC), a rare cutaneous neuroendocrine endocrine tumour is increasing in incidence, and continues to carry a poor prognosis. Objectives The objectives of this study were to examine all Irish cases of MCC from
Externí odkaz:
https://doaj.org/article/862f768afd29462c99c0a5c90c2c5539
Autor:
Kendrah Kidd, Petr Vylet’al, Céline Schaeffer, Eric Olinger, Martina Živná, Kateřina Hodaňová, Victoria Robins, Emily Johnson, Abbigail Taylor, Lauren Martin, Claudia Izzi, Sofia C. Jorge, Joaquim Calado, Rosa J. Torres, Karl Lhotta, Dominik Steubl, Daniel P. Gale, Christine Gast, Eva Gombos, Hannah C. Ainsworth, Ying Maggie Chen, Jorge Reis Almeida, Cintia Fernandes de Souza, Catarina Silveira, Rita Raposeiro, Nelson Weller, Peter J. Conlon, Susan L. Murray, Katherine A. Benson, Gianpiero L. Cavalleri, Miroslav Votruba, Alena Vrbacká, Antonio Amoroso, Daniela Gianchino, Gianluca Caridi, Gian Marco Ghiggeri, Jasmin Divers, Francesco Scolari, Olivier Devuyst, Luca Rampoldi, Stanislav Kmoch, Anthony J. Bleyer
Publikováno v:
Kidney International Reports, Vol 5, Iss 9, Pp 1472-1485 (2020)
Introduction: Autosomal dominant tubulo-interstitial kidney disease due to UMOD mutations (ADTKD-UMOD) is a rare condition associated with high variability in the age of end-stage kidney disease (ESKD). The minor allele of rs4293393, located in the p
Externí odkaz:
https://doaj.org/article/8ab1799f3ce441279d9513d18436243b
Autor:
Susan L. Murray, Fergus E. Daly, Patrick O’Kelly, Eamonn O’Leary, Sandra Deady, James P. O’Neill, Alexander Dudley, Nicholas R. Rutledge, Aiden McCormick, Diarmuid D. Houlihan, Yvonne Williams, Patrick G. Morris, Siona Ni Raghallaigh, Fergal J. Moloney, Donal J. Sexton, Peter J. Conlon
Publikováno v:
Renal Failure, Vol 42, Iss 1, Pp 607-612 (2020)
Background Solid organ transplantation is associated with increased risk of non-melanoma skin cancer. Studies with short follow up times have suggested a reduced occurrence of these cancers in recipients treated with mammalian target of rapamycin inh
Externí odkaz:
https://doaj.org/article/fd306fefc3f54840a8a196dac010c600
Autor:
S. Cormican, D. M. Connaughton, C. Kennedy, S. Murray, M. Živná, S. Kmoch, N. K. Fennelly, P. O’Kelly, K. A. Benson, E. T. Conlon, G. Cavalleri, C. Foley, B. Doyle, A. Dorman, M. A. Little, P. Lavin, K. Kidd, A. J. Bleyer, P. J. Conlon
Publikováno v:
Renal Failure, Vol 41, Iss 1, Pp 832-841 (2019)
Introduction: Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a rare genetic cause of renal impairment resulting from mutations in the MUC1, UMOD, HNF1B, REN, and SEC61A1 genes. Neither the national or global prevalence of these disea
Externí odkaz:
https://doaj.org/article/b14e21a261104580bccc774c2f595a7f
Autor:
Chaudhry Adeel Ebad, David Brennan, Julio Chevarria, Mohammad Bin Hussein, Donal Sexton, Douglas Mulholland, Ciaran Doyle, Patrick O’Kelly, Yvonne Williams, Ruth Dunne, Conall O’Seaghdha, Dilly Little, Martina Morrin, Peter J. Conlon
Publikováno v:
Journal of Transplantation, Vol 2021 (2021)
Background. The role of kidney volume measurement in predicting the donor and recipient kidney function is not clear. Methods. We measured kidney volume bilaterally in living kidney donors using CT angiography and assessed the association with the do
Externí odkaz:
https://doaj.org/article/bd4d70decff04e639ab20df944278e9e
Autor:
Caragh P. Stapleton, Graham M. Lord, UK and Ireland Renal Transplant Consortium, Peter J. Conlon, Gianpiero L. Cavalleri
Publikováno v:
HRB Open Research, Vol 3 (2020)
Background: We set out to quantify shared genetic ancestry between unrelated kidney donor-recipient pairs and test it as a predictor of time to graft failure. Methods: In a homogenous, unrelated, European cohort of deceased-donor kidney transplant pa
Externí odkaz:
https://doaj.org/article/760559999e044a46a1443e7295fc1784
Autor:
Donal J. Sexton, Declan G. de Freitas, Mark A. Little, Tomas McHugh, Colm Magee, Peter J. Conlon, Conall M. O’Seaghdha
Publikováno v:
Kidney International Reports, Vol 3, Iss 4, Pp 784-793 (2018)
We report 2 cases of apixaban use as prophylaxis against thromboembolism in the nephrotic syndrome (NS), and review the existing literature on direct-acting oral anticoagulant (DOAC) use in this scenario. Our cases appear to be the first reported use
Externí odkaz:
https://doaj.org/article/60f2a0f0cf9449558962706460262a16
Publikováno v:
Medical Education Online, Vol 22, Iss 1 (2017)
Background: Medical students often struggle to apply their nascent clinical skills in clerkships. While transitional clerkships can orient students to new roles and logistics, students may benefit from developing clinical skills in inpatient environm
Externí odkaz:
https://doaj.org/article/da261ad510cc4262be1b17bc2230b1cd