Zobrazeno 1 - 10
of 95
pro vyhledávání: '"P J, Bottomley"'
Autor:
Daniele Veggi, Chelsy C. Chesterman, Laura Santini, Ying Huang, Nicola Pacchiani, Jeannette Sierra, Lynn Chen, Jason Laliberte, Federica Bianchi, Roberta Cozzi, Elisabetta Frigimelica, Domenico Maione, Oretta Finco, Matthew J. Bottomley
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 8, Pp 235-248 (2024)
Abstract Thousands of disease cases and hundreds of deaths occur globally each year due to invasive meningococcal disease. Neisseria meningitidis serogroup B (MenB) is the leading cause of such disease in developed countries. Two vaccines, 4CMenB and
Externí odkaz:
https://doaj.org/article/9b599c9365e449dfb0b143e66a3cfe14
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Chronic kidney disease affects 1 in 10 people globally, with a prevalence twenty times that of cancer. A subset of individuals will progress to end-stage renal disease (ESRD) where renal replacement therapy is required to maintain health. Cutaneous d
Externí odkaz:
https://doaj.org/article/e786ca70c02843f9a2732abca0e3258b
Autor:
Sunil K. Ahuja, Muthu Saravanan Manoharan, Grace C. Lee, Lyle R. McKinnon, Justin A. Meunier, Maristella Steri, Nathan Harper, Edoardo Fiorillo, Alisha M. Smith, Marcos I. Restrepo, Anne P. Branum, Matthew J. Bottomley, Valeria Orrù, Fabio Jimenez, Andrew Carrillo, Lavanya Pandranki, Caitlyn A. Winter, Lauryn A. Winter, Alvaro A. Gaitan, Alvaro G. Moreira, Elizabeth A. Walter, Guido Silvestri, Christopher L. King, Yong-Tang Zheng, Hong-Yi Zheng, Joshua Kimani, T. Blake Ball, Francis A. Plummer, Keith R. Fowke, Paul N. Harden, Kathryn J. Wood, Martin T. Ferris, Jennifer M. Lund, Mark T. Heise, Nigel Garrett, Kristen R. Canady, Salim S. Abdool Karim, Susan J. Little, Sara Gianella, Davey M. Smith, Scott Letendre, Douglas D. Richman, Francesco Cucca, Hanh Trinh, Sandra Sanchez-Reilly, Joan M. Hecht, Jose A. Cadena Zuluaga, Antonio Anzueto, Jacqueline A. Pugh, South Texas Veterans Health Care System COVID-19 team, Brian K. Agan, Robert Root-Bernstein, Robert A. Clark, Jason F. Okulicz, Weijing He
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-31 (2023)
Abstract Some people remain healthier throughout life than others but the underlying reasons are poorly understood. Here we hypothesize this advantage is attributable in part to optimal immune resilience (IR), defined as the capacity to preserve and/
Externí odkaz:
https://doaj.org/article/2d05c47c46834fc38503fbfb37c7eb1f
Publikováno v:
eJHaem, Vol 4, Iss 1, Pp 291-293 (2023)
Externí odkaz:
https://doaj.org/article/c53fadcaf8bc4ff883429902d0213e86
Autor:
Daniele Veggi, Enrico Malito, Paola Lo Surdo, Werner Pansegrau, Valentina Rippa, Newton Wahome, Silvana Savino, Vega Masignani, Mariagrazia Pizza, Matthew J. Bottomley
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2070-2081 (2022)
Invasive meningococcal disease can cause fatal sepsis and meningitis and is a global health threat. Factor H binding protein (fHbp) is a protective antigen included in the two currently available vaccines against serogroup B meningococcus (MenB). FHb
Externí odkaz:
https://doaj.org/article/d7cd09e242a249cfa9f272717e3367cb
Autor:
Andreas F. Haag, Lassi Liljeroos, Paolo Donato, Clarissa Pozzi, Tarcisio Brignoli, Matthew J. Bottomley, Fabio Bagnoli, Isabel Delany
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Staphylococcus aureus is a clinically important bacterial pathogen that has become resistant to treatment with most routinely used antibiotics. Alternative strategies, such as vaccination and phage therapy, are therefore actively being inves
Externí odkaz:
https://doaj.org/article/578569a62c2345048e7ca741aac43fe0
Autor:
Hannah Beckwith, Michael Nation, Aisling McMahon, David C Wheeler, Matthew J Bottomley, Neil S Sheerin, Jeremy Hughes, Sharlene Greenwood
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Objectives To establish barriers and motivators underlying research engagement among early-career practitioners in nephrology across the UK, in order to guide potential interventions to enhance research involvement in renal units.Design Cross-section
Externí odkaz:
https://doaj.org/article/644000dbb14d42f4af9f76bad3e38632
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundMalignancy is a major cause of morbidity and mortality in transplant recipients. Identification of those at highest risk could facilitate pre-emptive intervention such as reduction of immunosuppression. Reduced circulating monocytic HLA-DR
Externí odkaz:
https://doaj.org/article/2e927d849d85448eb416c3488db47965
Autor:
Emanuele Andreano, Ida Paciello, Monia Bardelli, Simona Tavarini, Chiara Sammicheli, Elisabetta Frigimelica, Silvia Guidotti, Giulia Torricelli, Marco Biancucci, Ugo D’Oro, Sumana Chandramouli, Matthew J Bottomley, Rino Rappuoli, Oretta Finco, Francesca Buricchi
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 6, Pp 1-15 (2021)
Abstract Respiratory syncytial virus (RSV) is the leading cause of death from lower respiratory tract infection in infants and children, and is responsible for considerable morbidity and mortality in older adults. Vaccines for pregnant women and elde
Externí odkaz:
https://doaj.org/article/7401702b0b794eb9a186351c1a095d31
Autor:
Susanne A. Elsner, Sam S. Salek, Andrew Y. Finlay, Anna Hagemeier, Catherine J. Bottomley, Alexander Katalinic, Annika Waldmann
Publikováno v:
Health and Quality of Life Outcomes, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background The Family Reported Outcome Measure (FROM-16) assesses the impact of a patient’s chronic illness on the quality of life (QoL) of the patient’s partner or family members. The aim of the study was to translate, explore the struc
Externí odkaz:
https://doaj.org/article/3a7a5da384c844369f6d2db2c074bc8a