Zobrazeno 1 - 10
of 30
pro vyhledávání: '"P J, Bindels"'
Autor:
Anusha S. Shankar, Hector Tejeda-Mora, Zhaoyu Du, Quincy Nlandu, Virginia Palomares-Cabeza, Thierry P. P. van den Bosch, Sander S. Korevaar, Fabiany Da Costa Gonçalves, Eric M. J. Bindels, R. Kramann, Marlies E. J. Reinders, Marian C. Clahsen-van Groningen, Ewout J. Hoorn, Joost Gribnau, Carla C. Baan, Martin J. Hoogduijn
Publikováno v:
Transplant International, Vol 37 (2024)
Kidney organoids are an innovative tool in transplantation research. The aim of the present study was to investigate whether kidney organoids are susceptible for allo-immune attack and whether they can be used as a model to study allo-immunity in kid
Externí odkaz:
https://doaj.org/article/3cc42c074ba04f7f8e9f53cc968ab725
Autor:
Tse‐Ying Lee, Yu‐An Chen, Olivier Q. Groot, Hung‐Kuan Yen, Bas J. J. Bindels, Robert‐Jan Pierik, Hsiang‐Chieh Hsieh, Aditya V. Karhade, Ting‐En Tseng, Yi‐Hsiang Lai, Jing‐Jen Yang, Chia‐Che Lee, Ming‐Hsiao Hu, Jorrit‐Jan Verlaan, Joseph H. Schwab, Rong‐Sen Yang, Wei‐Hsin Lin
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 14264-14281 (2023)
Abstract Background Survival is an important factor to consider when clinicians make treatment decisions for patients with skeletal metastasis. Several preoperative scoring systems (PSSs) have been developed to aid in survival prediction. Although we
Externí odkaz:
https://doaj.org/article/e2f77021a8e248b5a4462ab12671f3c7
Autor:
Teoman Deger, Pauline A. J. Mendelaar, Jaco Kraan, Wendy J. C. Prager‐van der Smissen, Michelle van derVlugt‐Daane, Eric M. J. Bindels, Anieta M. Sieuwerts, Stefan Sleijfer, Saskia M. Wilting, Antoinette Hollestelle, John W. M. Martens
Publikováno v:
Molecular Oncology, Vol 16, Iss 16, Pp 2981-3000 (2022)
Intrapatient tumour heterogeneity is likely a major determinant of clinical outcome in cancer patients. To assess heterogeneity in a minimally invasive manner, methods to perform single circulating tumour cell (CTC) genomics at high resolution are ne
Externí odkaz:
https://doaj.org/article/670fed1d4b0e407da90d1dd04df95007
Autor:
Fabian Peisker, Maurice Halder, James Nagai, Susanne Ziegler, Nadine Kaesler, Konrad Hoeft, Ronghui Li, Eric M. J. Bindels, Christoph Kuppe, Julia Moellmann, Michael Lehrke, Christian Stoppe, Michael T. Schaub, Rebekka K. Schneider, Ivan Costa, Rafael Kramann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
The cardiac vascular niche is of major importance in homeostasis and disease, but knowledge of its complexity in response to injury remains limited. Here we combine lineage tracing with single cell RNA sequencing to show alterations in fibroblasts, e
Externí odkaz:
https://doaj.org/article/19f66c2c61bd4908bcd8a5e61c027ad1
Autor:
Martijn P. T. Ernst, Eline Pronk, Claire van Dijk, Paulina M. H. van Strien, Tim V. D. van Tienhoven, Michiel J. W. Wevers, Mathijs A. Sanders, Eric M. J. Bindels, Nancy A. Speck, Marc H. G. P. Raaijmakers
Publikováno v:
HemaSphere, Vol 7, Iss 2, p e824 (2023)
RUNX1 familial platelet disorder (RUNX1-FPD) is a hematopoietic disorder caused by germline loss-of-function mutations in the RUNX1 gene and characterized by thrombocytopathy, thrombocytopenia, and an increased risk of developing hematologic malignan
Externí odkaz:
https://doaj.org/article/265d1d93f6a4460b8bd93131f01a5695
Autor:
Olivier Q Groot, Bas J J Bindels, Paul T Ogink, Neal D Kapoor, Peter K Twining, Austin K Collins, Michiel E R Bongers, Amanda Lans, Jacobien H F Oosterhoff, Aditya V Karhade, Jorrit-Jan Verlaan, Joseph H Schwab
Publikováno v:
Acta Orthopaedica, Vol 92, Iss 4, Pp 385-393 (2021)
Background and purpose — External validation of machine learning (ML) prediction models is an essential step before clinical application. We assessed the proportion, performance, and transparent reporting of externally validated ML prediction model
Externí odkaz:
https://doaj.org/article/6e857ecac3b54e31915ada6a2d68660a
Publikováno v:
Journal of Foot and Ankle Research, Vol 15, Iss 1, Pp n/a-n/a (2022)
Abstract Background Plantar heel pain (PHP) is a common cause of foot complaints, for which treatment with custom‐made insoles is frequently applied. So far few studies have investigated patient characteristics that predict response to these treatm
Externí odkaz:
https://doaj.org/article/531496a39b9643f7bdad464cbb8749b6
Autor:
Brittany D. K. Gratreak, Elizabeth A. Swanson, Rebecca A. Lazelle, Sabina K. Jelen, Joost Hoenderop, René J. Bindels, Chao‐Ling Yang, David H. Ellison
Publikováno v:
Physiological Reports, Vol 8, Iss 1, Pp n/a-n/a (2020)
Abstract Calcineurin inhibitors (CNIs) are immunosuppressive drugs used to prevent graft rejection after organ transplant. Common side effects include renal magnesium wasting and hypomagnesemia, which may contribute to new‐onset diabetes mellitus,
Externí odkaz:
https://doaj.org/article/d55dbaee735b461abbb55adc4a2ef5aa
Autor:
Leo Koenderman, Maarten J. Siemers, Corneli van Aalst, Suzanne H. Bongers, Roy Spijkerman, Bas J. J. Bindels, Giulio Giustarini, Harriët M. R. van Goor, Karin A. H. Kaasjager, Nienke Vrisekoop
Publikováno v:
Cells, Vol 10, Iss 5, p 1109 (2021)
A malfunction of the innate immune response in COVID-19 is associated with eosinopenia, particularly in more severe cases. This study tested the hypothesis that this eosinopenia is COVID-19 specific and is associated with systemic activation of eosin
Externí odkaz:
https://doaj.org/article/17bbca8f8bc14ac79183481f847dfc21
Autor:
Noemi A. Zambetti, Eric M. J. Bindels, Paulina M. H. Van Strien, Marijke G. Valkhof, Maria N. Adisty, Remco M. Hoogenboezem, Mathijs A. Sanders, Johanna M. Rommens, Ivo P. Touw, Marc H. G. P. Raaijmakers
Publikováno v:
Haematologica, Vol 100, Iss 10 (2015)
Shwachman-Diamond syndrome is a congenital bone marrow failure disorder characterized by debilitating neutropenia. The disease is associated with loss-of-function mutations in the SBDS gene, implicated in ribosome biogenesis, but the cellular and mol
Externí odkaz:
https://doaj.org/article/bd2c443f30e24086ae9bd6bbe5c5cac0