Zobrazeno 1 - 10
of 154
pro vyhledávání: '"P J, Atkinson"'
Autor:
William R. Lenderking, Yulia Savva, Mark J. Atkinson, Renee Campbell, Isabelle Chabot, Margaret Moline, Genevieve Meier, Charles M. Morin
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Background The Insomnia Severity Index (ISI) is a widely used measure of insomnia severity. Various ISI research findings suggest different factor solutions and meaningful within-individual change (MWIC) to detect treatment response in patie
Externí odkaz:
https://doaj.org/article/7f9f97c9d0c94205b47b1870f1dab97e
Autor:
William R. Lenderking, Mark J. Atkinson, Mary Kate Ladd, Yulia Savva, Stephanie Sommer, Matthew Sidovar, Claudia Hastedt
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract Background Cognitive impairment associated with schizophrenia (CIAS) represents a distinct, persistent, and core group of schizophrenia symptoms. Cognitive symptoms have been shown to have an impact on quality of life. There are several publ
Externí odkaz:
https://doaj.org/article/a2edf1ac7893498dbb640e35f209f41b
Autor:
Tian Wang, Angela H. Ling, Sara E. Billings, Davood K. Hosseini, Yona Vaisbuch, Grace S. Kim, Patrick J. Atkinson, Zahra N. Sayyid, Ksenia A. Aaron, Dhananjay Wagh, Nicole Pham, Mirko Scheibinger, Ruiqi Zhou, Akira Ishiyama, Lindsay S. Moore, Peter Santa Maria, Nikolas H. Blevins, Robert K. Jackler, Jennifer C. Alyono, John Kveton, Dhasakumar Navaratnam, Stefan Heller, Ivan A. Lopez, Nicolas Grillet, Taha A. Jan, Alan G. Cheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Mammalian inner ear hair cell loss leads to permanent hearing and balance dysfunction. In contrast to the cochlea, vestibular hair cells of the murine utricle have some regenerative capacity. Whether human utricular hair cells regenerate in
Externí odkaz:
https://doaj.org/article/bbd2c632a6e24a05853cb5f0c56c9d00
Autor:
Robert Phan, Yi Xie, Ishith Seth, Connor J. Atkinson, Damon Thomas, David J. Hunter-Smith, Warren M. Rozen, Roberto Cuomo
Publikováno v:
JPRAS Open, Vol 40, Iss , Pp 206-214 (2024)
Introduction: The use of the dorsal hamate as a free osteochondral bone graft or vascularized bone flap has become the mainstay for large, comminuted middle phalanx volar lip fractures. To date, few studies have been conducted in the assessment of do
Externí odkaz:
https://doaj.org/article/3eebaae4937947fd87138e73bd4511b4
Autor:
Hasan Farooq, Hannah P. Luehmann, Jeffrey R. Koenitzer, Gyu Seong Heo, Deborah H. Sultan, Devesha H. Kulkarni, Sean P. Gunsten, Rekha M. Sashti, Tao Huang, Amanda R. Keller, Kory J. Lavine, Jeffrey J. Atkinson, Laura M. Wingler, Yongjian Liu, Steven L. Brody
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105431- (2024)
Summary: Background: Pulmonary fibrosis is a challenging clinical problem with lung pathology featuring immune cell infiltrates, fibroblast expansion, and matrix deposition. Molecular analysis of diseased lungs and preclinical models have uncovered C
Externí odkaz:
https://doaj.org/article/6ae5fd1a54164d1183633ab65d6b32ca
Autor:
Weixuan Chen, Daniel Rams, Maciej Zając, Raghad Albalawi, Andrew J. Atkinson, Abimbola J. Aminu, Malgorzata Mazur, Mateusz K. Hołda, Jerzy Walocha, Krzysztof Gil, Marcin Kuniewicz, Halina Dobrzynski
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionThe sinus node (SN) is the main pacemaker site of the heart, located in the upper right atrium at the junction of the superior vena cava and right atrium. The precise morphology of the SN in the human heart remains relatively unclear espe
Externí odkaz:
https://doaj.org/article/0fdd029f1516470292dd4af4196ee17e
Autor:
Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The Eyes Absent proteins (EYA1-4) are a biochemically unique group of tyrosine phosphatases known to be tumour-promoting across a range of cancer types. To date, the targets of EYA phosphatase activity remain largely uncharacterised. Here, w
Externí odkaz:
https://doaj.org/article/c6f9e1aee6c04251a8ad3f7b91d37b75
Autor:
Tomokatsu Udagawa, Erisa Takahashi, Norifumi Tatsumi, Hideki Mutai, Hiroki Saijo, Yuko Kondo, Patrick J. Atkinson, Tatsuo Matsunaga, Mamoru Yoshikawa, Hiromi Kojima, Masataka Okabe, Alan G. Cheng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Cochlear melanocytes are intermediate cells in the stria vascularis that generate endocochlear potentials required for auditory function. Human PAX3 mutations cause Waardenburg syndrome and abnormalities of skin and retinal melanocytes, mani
Externí odkaz:
https://doaj.org/article/56000f44d60b4f52be0cf622884bfdc6
Autor:
Daniel J. Tan, MBI, Joseph M. Plasek, PhD, Peter C. Hou, MD, Rebecca M. Baron, MD, Benjamin J. Atkinson, MD, Li Zhou, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 3, p e1043 (2024)
IMPORTANCE AND OBJECTIVES:. COVID-19-related acute respiratory distress syndrome (ARDS) is associated with high mortality and often necessitates invasive mechanical ventilation (IMV). Previous studies on non-COVID-19 ARDS have shown driving pressure
Externí odkaz:
https://doaj.org/article/ce93db54af9e423eb0a2742ff7ce63cb
Selection of viral capsids and promoters affects the efficacy of rescue of Tmprss3-deficient cochlea
Autor:
Ksenia A. Aaron, Katja Pekrun, Patrick J. Atkinson, Sara E. Billings, Julia M. Abitbol, Ina A. Lee, Yasmin Eltawil, Yuan-Siao Chen, Wuxing Dong, Rick F. Nelson, Mark A. Kay, Alan G. Cheng
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 413-428 (2023)
Adeno-associated virus (AAV)-mediated gene transfer has shown promise in rescuing mouse models of genetic hearing loss, but how viral capsid and promoter selection affects efficacy is poorly characterized. Here, we tested combinations of AAVs and pro
Externí odkaz:
https://doaj.org/article/12dd1baf9a7e41769ec3b2c66b940104