Zobrazeno 1 - 10
of 26
pro vyhledávání: '"P Hande Ozdinler"'
Autor:
P. Hande Ozdinler
Publikováno v:
Brain Sciences, Vol 14, Iss 10, p 978 (2024)
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with progressive neurodegeneration, affecting both the cortical and the spinal component of the motor neuron circuitry in patients. The cellular and molecular basis of selective neuronal v
Externí odkaz:
https://doaj.org/article/ea65675e1a30447fad684565796e796a
Autor:
Deepak P Srivastava, Kevin M Woolfrey, Kelly A Jones, Charles T Anderson, Katharine R Smith, Theron A Russell, Hyerin Lee, Marina V Yasvoina, David L Wokosin, P Hande Ozdinler, Gordon M G Shepherd, Peter Penzes
Publikováno v:
PLoS Biology, Vol 10, Iss 6, p e1001350 (2012)
The architecture of dendritic arbors determines circuit connectivity, receptive fields, and computational properties of neurons, and dendritic structure is impaired in several psychiatric disorders. While apical and basal dendritic compartments of py
Externí odkaz:
https://doaj.org/article/82bebeeb8c44423d9a906dbfb32001e3
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 3, Pp 725-739 (2025)
Developing effective and long-term treatment strategies for rare and complex neurodegenerative diseases is challenging. One of the major roadblocks is the extensive heterogeneity among patients. This hinders understanding the underlying disease-causi
Externí odkaz:
https://doaj.org/article/675851f1fdd04bff992f39e9eb7d15d6
Publikováno v:
PLoS Biology, Vol 2, Iss 12, p e403 (2004)
Neurotrophin-3 (NT-3) is required for proprioceptive neuron survival. Deletion of the proapoptotic gene Bax in NT-3 knockout mice rescues these neurons and allows for examination of their axon growth in the absence of NT-3 signaling. TrkC-positive pe
Externí odkaz:
https://doaj.org/article/ef70321391274b5e98c4eff513c7eaa2
Autor:
Oleksandr Kirsanov, Taylor Johnson, Taylor Malachowski, Bryan A. Niedenberger, Emma A. Gilbert, Debajit Bhowmick, P. Hande Ozdinler, Douglas A. Gray, Kelsey Fisher-Wellman, Brian P. Hermann, Christopher B. Geyer
Publikováno v:
Development. 149
In mammalian testes, premeiotic spermatogonia respond to retinoic acid by completing an essential lengthy differentiation program before initiating meiosis. The molecular and cellular changes directing these developmental processes remain largely und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c72bd037ab8ed9cf8894ddb1fdffba0
https://doi.org/10.1242/dev.200713
https://doi.org/10.1242/dev.200713
Autor:
Barış Genç, Mukesh Gautam, Benjamin R. Helmold, Nuran Koçak, Aksu Günay, Gashaw M. Goshu, Richard B. Silverman, P. Hande Ozdinler
Publikováno v:
Scientific Reports. 12
Even though amyotrophic lateral sclerosis (ALS) is a disease of the upper and lower motor neurons, to date none of the compounds in clinical trials have been tested for improving the health of diseased upper motor neurons (UMNs). There is an urgent n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ecbfd9235647abc03f6591ed8816eca
https://doi.org/10.1038/s41598-022-09332-4
https://doi.org/10.1038/s41598-022-09332-4
Autor:
Mukesh, Gautam, Renata Del, Carratore, Benjamin, Helmold, Alessandra, Tessa, Oge, Gozutok, Navdeep, Chandel, Halil, Idrisoglu, Paolo, Bongioanni, Roberta, Battini, P Hande, Ozdinler
Publikováno v:
Metabolites. 12(2)
Pathogenic variants in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4978b715c74dd7834f2b3f98efdc864b
https://pubmed.ncbi.nlm.nih.gov/35208248
https://pubmed.ncbi.nlm.nih.gov/35208248
Autor:
Barış, Genç, Mukesh, Gautam, Benjamin R, Helmold, Nuran, Koçak, Aksu, Günay, Gashaw M, Goshu, Richard B, Silverman, P, Hande Ozdinler
Publikováno v:
Scientific reports. 12(1)
Even though amyotrophic lateral sclerosis (ALS) is a disease of the upper and lower motor neurons, to date none of the compounds in clinical trials have been tested for improving the health of diseased upper motor neurons (UMNs). There is an urgent n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28577114e0a62a65f636793d16a48b61
https://pubmed.ncbi.nlm.nih.gov/35354901
https://pubmed.ncbi.nlm.nih.gov/35354901
Publikováno v:
Scientific reports. 12(1)
Mitochondrial defects result in dysregulation of metabolomics and energy homeostasis that are detected in upper motor neurons (UMNs) with TDP-43 pathology, a pathology that is predominantly present in both familial and sporadic cases of amyotrophic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3914bae8eea39a1a80b4fbd7b6b7889b
https://pubmed.ncbi.nlm.nih.gov/35277554
https://pubmed.ncbi.nlm.nih.gov/35277554
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Mitochondrial dysfunction is one of the converging paths for many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), and TDP-43 pathology is the most common proteinopathy detected in ALS and ALS/Frontotemporal lobar degenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4af2bbdf852032bc64ae22968b893c
https://doi.org/10.3389/fncel.2019.00489
https://doi.org/10.3389/fncel.2019.00489