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Akademický článek

Site-specific template generative approach for retrosynthetic planning

Autor: Yu Shee, Haote Li, Pengpeng Zhang, Andrea M. Nikolic, Wenxin Lu, H. Ray Kelly, Vidhyadhar Manee, Sanil Sreekumar, Frederic G. Buono, Jinhua J. Song, Timothy R. Newhouse, Victor S. Batista

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)

Abstract Retrosynthesis, the strategy of devising laboratory pathways by working backwards from the target compound, is crucial yet challenging. Enhancing retrosynthetic efficiency requires overcoming the vast complexity of chemical space, the limite

Externí odkaz: https://doaj.org/article/e93efc9d82a34a26a2ffd7bfe5466d20

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Akademický článek

Study protocol for a single-site feasibility study evaluating the adoption and fidelity of Prep-4-RT: prehabilitation for head and neck cancer patients undergoing radiotherapy

Autor: H. Ray, E. Sexton, J. Frowen, K. Gough, S. Turnbull, S. Abo, M. Ftanou, J. Loeliger

Publikováno v: Pilot and Feasibility Studies, Vol 10, Iss 1, Pp 1-10 (2024)

Abstract Introduction Prep-4-RT is a co-designed stepped-care multimodal prehabilitation program for people scheduled to receive radiotherapy for head and neck cancer (HNC). Prehabilitation, which occurs between diagnosis and treatment commencement,

Externí odkaz: https://doaj.org/article/b72e565570664cea96cfb0831d21eb8f

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Akademický článek

Over a century of progress on Trichinella research in pigs at the United States Department of Agriculture: Challenges and solutions

Autor: Jitender P. Dubey, Peter C. Thompson, Valsin Fournet, Dolores E. Hill, Dante Zarlenga, H. Ray Gamble, Benjamin M. Rosenthal

Publikováno v: Food and Waterborne Parasitology, Vol 36, Iss , Pp e00239- (2024)

Trichinellosis, caused by 13 species/subspecies/genotypes in the nematode genus Trichinella, is a worldwide zoonosis. In the United States, trichinellosis was of historical and economic significance because of European restrictions on the import of U

Externí odkaz: https://doaj.org/article/2fad8bef17b94142acedf38829aae397

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Akademický článek

Surveillance for Trichinella infection in U.S. pigs raised under controlled management documents negligible risk for public health

Autor: H. Ray Gamble, Dolores E. Hill, Valsin Fournet, Brandon Adams, Diane Hawkins-Cooper, Jorrell Fredericks, Jovan Aquino, Sonia Agu, Nadya Chehab, Ako Ankrah, Maria C. Antognoli, Marta D. Remmenga, Scott Kramer, Lori Gustafson, Benjamin M. Rosenthal

Publikováno v: Food and Waterborne Parasitology, Vol 36, Iss , Pp e00238- (2024)

Biosecurity measures preventing exposure of pigs to rodents, wildlife, and contaminated feed or waste products reduce the risk of zoonotic Trichinella infection in pork. To understand the benefits of such measures in the United States, we conducted t

Externí odkaz: https://doaj.org/article/f74dcc6dedcd4aaab650c103daa5ca90

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Akademický článek

Single nuclei transcriptomics in human and non-human primate striatum in opioid use disorder

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Abstract In brain, the striatum is a heterogenous region involved in reward and goal-directed behaviors. Striatal dysfunction is linked to psychiatric disorders, including opioid use disorder (OUD). Striatal subregions are divided based on neuroanato

Externí odkaz: https://doaj.org/article/82f5489316cf4dc69335f0d491c9b09c

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Akademický článek

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Akademický článek

Characterization of the correlated background for a sterile neutrino search using the first dataset of the JSNS $$^2$$ 2 experiment

Publikováno v: European Physical Journal C: Particles and Fields, Vol 82, Iss 4, Pp 1-6 (2022)

Abstract JSNS $$^2$$ 2 (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) is an experiment that is searching for sterile neutrinos via the observation of $${\bar{\nu }}_{\mu } \rightarrow {\bar{\nu }}_{e}$$ ν ¯ μ → ν ¯ e appe

Externí odkaz: https://doaj.org/article/02b7db60393d4e7ab9cee19d47b40c27

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