Zobrazeno 1 - 10
of 81
pro vyhledávání: '"P H Loh"'
Publikováno v:
Acta Dermato-Venereologica, Vol 104 (2024)
Porokeratosis ptychotropica (PP) is a rare and unusual variant of porokeratosis. There is a dearth of information on the natural history, epidemiology, and optimal treatment options. This study aimed to characterize the worldwide distribution, epidem
Externí odkaz:
https://doaj.org/article/561e602ae2e94896b8cc1d8c21406c65
Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5
Autor:
Yanran Chen, Haomiao Su, Jianing Zhao, Zhenkun Na, Kevin Jiang, Antonella Bacchiocchi, Ken H. Loh, Ruth Halaban, Zhentian Wang, Xiongwen Cao, Sarah A. Slavoff
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113145- (2023)
Summary: The conserved WD40-repeat protein WDR5 interacts with multiple proteins both inside and outside the nucleus. However, it is currently unclear whether and how the distribution of WDR5 between complexes is regulated. Here, we show that an unan
Externí odkaz:
https://doaj.org/article/677a2dd973a34f00ba7e7ac83d8ed9a4
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Polycomb Repressive Complex 2, an important regulator of embryonic development, exists in two configurations, PRC2.1 and PRC2.2. Here the authors dissect the functional contributions of these two PRC2 subunits and observed complex-specific alteration
Externí odkaz:
https://doaj.org/article/11e461c83743498dbe76beae2bc660e6
Autor:
Elizabeth H. Loh, Alessandra Nava, Kris A. Murray, Kevin J. Olival, Moisés Guimarães, Juliana Shimabukuro, Carlos Zambrana-Torrelio, Fernanda R. Fonseca, Daniele Bruna Leal de Oliveira, Angélica Cristine de Almeida Campos, Edison L. Durigon, Fernando Ferreira, Matthew J. Struebig, Peter Daszak
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
IntroductionBats are critical to maintaining healthy ecosystems and many species are threatened primarily due to global habitat loss. Bats are also important hosts of a range of viruses, several of which have had significant impacts on global public
Externí odkaz:
https://doaj.org/article/b91f241c374e4273bd0a9911a9d2594a
Autor:
Ru Liu, Yue Xing, Herui Zhang, Junling Wang, Huanling Lai, Lipeng Cheng, Donghong Li, Tao Yu, Xiaoming Yan, Cuiping Xu, Yueshan Piao, Linghui Zeng, Horace H. Loh, Guojun Zhang, Xiaofeng Yang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
ObjectiveAltered expression patterns of Na+-K+-2Cl– (NKCC1) and K+-Cl– (KCC2) co-transporters have been implicated in the pathogenesis of epilepsy. Here, we assessed the effects of imbalanced NKCC1 and KCC2 on γ-aminobutyric acidergic (GABAergic
Externí odkaz:
https://doaj.org/article/3aca929bbb684b5696f68622c98802d1
Publikováno v:
Cell Regeneration, Vol 10, Iss 1, Pp 1-12 (2021)
Abstract Background Epigenetic modifications, namely non-coding RNAs, DNA methylation, and histone modifications such as methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation play a significant role in brain development. DNA meth
Externí odkaz:
https://doaj.org/article/3905335db51a42579615401574ef710a
Autor:
Junling Wang, Bin Jing, Ru Liu, Donghong Li, Wei Wang, Jiaoyang Wang, Jianfeng Lei, Yue Xing, Jiaqing Yan, Horace H. Loh, Guangming Lu, Xiaofeng Yang
Publikováno v:
NeuroImage, Vol 237, Iss , Pp 118133- (2021)
Accurate epileptogenic zone (EZ) or seizure onset zone (SOZ) localization is crucial for epilepsy surgery optimization. Previous animal and human studies on epilepsy have reported that changes in blood oxygen level-dependent (BOLD) signals induced by
Externí odkaz:
https://doaj.org/article/fe0caa87b743468bad55657cea96ce86
Autor:
Chet H. Loh, Gert Jan C. Veenstra
Publikováno v:
Epigenomes, Vol 6, Iss 3, p 23 (2022)
Embryonic development is a highly intricate and complex process. Different regulatory mechanisms cooperatively dictate the fate of cells as they progress from pluripotent stem cells to terminally differentiated cell types in tissues. A crucial regula
Externí odkaz:
https://doaj.org/article/00344a9cdb754c849c2ce31184b53282
Autor:
Xiaonan Li, Tao Yu, Zhiwei Ren, Xueyuan Wang, Jiaqing Yan, Xin Chen, Xiaoming Yan, Wei Wang, Yue Xing, Xianchang Zhang, Herui Zhang, Horace H. Loh, Guojun Zhang, Xiaofeng Yang
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
Accurate localization of the epileptogenic zone (EZ) is a key factor to obtain good surgical outcome for refractory epilepsy patients. However, no technique, so far, can precisely locate the EZ, and there are barely any reports on the combined applic
Externí odkaz:
https://doaj.org/article/2c07807258c94b7e9797e83ee723bac4
Publikováno v:
Brain and Spine, Vol 1, Iss , Pp 100483- (2021)
Externí odkaz:
https://doaj.org/article/f1781502ecdd4dbaadcfd4a1843ff39d