Zobrazeno 1 - 10
of 61
pro vyhledávání: '"P H Iverius"'
Autor:
D K Strickland, J M Lalouel, P H Iverius, David A. Chappell, Marc W. Pladet, Glenna L. Fry, I Inoue, Susan L. Bowen
Publikováno v:
Journal of Biological Chemistry. 269:18001-18006
Lipoprotein lipase (LPL) binds to the low density lipoprotein receptor-related protein (LRP)/alpha 2-macroglobulin receptor and induces catabolism of normal human very low density lipoproteins (VLDL) via LRP in vitro. Recent studies showed that the C
Autor:
G L Fry, Suzanne E. Williams, P H Iverius, J M Lalouel, Huan Tran, I Inoue, Dudley K. Strickland, D.A. Chappell, M W Pladet
Publikováno v:
Journal of Biological Chemistry. 269:8653-8658
Lipoprotein lipase (LPL) binds with high affinity to the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor (LRP) and promotes binding, uptake, and degradation of normal triglyceride-rich lipoproteins in a process mediate
Autor:
L E Muhonen, Marc W. Pladet, M A Waknitz, Glenna L. Fry, D K Strickland, David A. Chappell, P H Iverius
Publikováno v:
Journal of Biological Chemistry. 268:14168-14175
Bovine milk lipoprotein lipase (LPL) induced binding, uptake, and degradation of 125I-labeled normal human triglyceride-rich lipoproteins by cultured mutant fibroblasts lacking LDL receptors. The induction was dose-dependent and occurred whether LPL
Publikováno v:
Journal of Biological Chemistry. 267:25764-25767
Lipoprotein lipase (LPL), the major lipolytic enzyme involved in the conversion of triglyceride-rich lipoproteins to remnants, was found to compete with binding of activated alpha 2-macroglobulin (alpha 2M*) to the low density lipoprotein receptor-re
Autor:
D N Ridinger, Mitsuru Emi, A Lubbers, Aaron N. Hata, B Guy-Grand, J Shuhua, A Basdevant, P H Iverius, S.D. Sutherland, L.K. Kwong
Publikováno v:
Journal of Biological Chemistry. 267:20132-20139
Most missense mutations of the lipoprotein lipase (LPL) gene identified among LPL-deficient subjects cluster in a segment of the sequence that encodes the catalytic triad as well as functional elements involved in the activation of the lipase at lipi
Autor:
P. H. Iverius, Godfrey S. Getz, Patricia A. Soltys, Kenneth S. Polonsky, N M O'Meara, W. L. Pugh, J D Blackman, G. F. Lewis
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 72:934-944
Postprandial lipoprotein metabolism may be important in atherogenesis and has not been studied in detail in noninsulin-dependent diabetes mellitus (NIDDM). We used the vitamin A fat-loading test to label triglyceride-rich lipoprotein particles of int
Autor:
Kenneth S. Polonsky, A. F. Druetzler, P. H. Iverius, Patricia A. Soltys, J D Blackman, N M O'Meara, Godfrey S. Getz, G. F. Lewis
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 71:1041-1050
Abnormalities in fasting lipid and lipoprotein levels are known to occur in obesity and other hyperinsulinemic states. However, postprandial lipoprotein metabolism has not been studied systematically in obese subjects using sensitive techniques to di
Autor:
Akira Hata, Roger R. Williams, Mitsuru Emi, Lily Wu, P H Iverius, Dana E. Wilson, Jean-Marc Lalouel, E Hillas
Publikováno v:
Journal of Clinical Investigation. 86:735-750
Familial lipoprotein lipase (LPL) deficiency is a rare genetic disorder accompanied by well-characterized manifestations. The phenotypic expression of heterozygous LPL deficiency has not been so clearly defined. We studied the pedigree of a proband k
Autor:
Aaron N. Hata, Mitsuru Emi, Dana E. Wilson, Robert M. Hegele, Long Jun Wu, Roger R. Williams, Jean-Marc Lalouel, P H Iverius
Publikováno v:
Journal of Biological Chemistry. 265:5910-5916
Cloning and sequencing of lipoprotein lipase (LPL) cDNA prepared from the adipose tissue of a patient with classical LPL deficiency revealed a G to A transition at nucleotide 818 in all sequenced clones, leading to the substitution of glutamic acid f
Autor:
S E, Williams, I, Inoue, H, Tran, G L, Fry, M W, Pladet, P H, Iverius, J M, Lalouel, D A, Chappell, D K, Strickland
Publikováno v:
The Journal of biological chemistry. 269(12)
Lipoprotein lipase (LPL) binds with high affinity to the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor (LRP) and promotes binding, uptake, and degradation of normal triglyceride-rich lipoproteins in a process mediate