Zobrazeno 1 - 10
of 23
pro vyhledávání: '"P H, van Berkel"'
Autor:
Chiara Tarantelli, David Wald, Nicolas Munz, Filippo Spriano, Alessio Bruscaggin, Eleonora Cannas, Luciano Cascione, Eugenio Gaudio, Alberto J. Arribas, Shivaprasad Manjappa, Gaetanina Golino, Lorenzo Scalise, Maria Teresa Cacciapuoti, Emanuele Zucca, Anastasios Stathis, Giorgio Inghirami, Patrick H. van Berkel, Davide Rossi, Paolo F. Caimi, Francesca Zammarchi, Francesco Bertoni
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Antibody-drug conjugates (ADCs) represent one of the most successful therapeutic approaches introduced in clinical practice in the last few years. Loncastuximab tesirine (ADCT-402) is a CD19 targeting ADC, in which the antibody is conjugated through
Externí odkaz:
https://doaj.org/article/0ddadfd5eefa4ca48941dd698807b5c9
Autor:
Linda Jahn, Lisa Storm-Johannsen, Diana Seidler, Jasmin Noack, Wei Gao, Thomas Schafhauser, Wolfgang Wohlleben, Willem J. H. van Berkel, Philippe Jacques, Tambi Kar, Birgit Piechulla, Jutta Ludwig-Müller
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 35, Iss 1, Pp 49-63 (2022)
Cyanodermella asteris is a fungal endophyte from Aster tataricus, a perennial plant from the northern part of Asia. Here, we demonstrated an interaction of C. asteris with Arabidopsis thaliana, Chinese cabbage, rapeseed, tomato, maize, or sunflower r
Externí odkaz:
https://doaj.org/article/e872aaaeaef44126b5d2d3905935057b
Autor:
Peicheng Sun, Christophe V. F. P. Laurent, Stefan Scheiblbrandner, Matthias Frommhagen, Dimitrios Kouzounis, Mark G. Sanders, Willem J. H. van Berkel, Roland Ludwig, Mirjam A. Kabel
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-19 (2020)
Abstract Background Lytic polysaccharide monooxygenases (LPMOs) are powerful enzymes that oxidatively cleave plant cell wall polysaccharides. LPMOs classified as fungal Auxiliary Activities family 9 (AA9) have been mainly studied for their activity t
Externí odkaz:
https://doaj.org/article/7b25460c627748fa9d1d81dacb572cd5
Autor:
Gijs van Erven, Anne F. Kleijn, Aleksandrina Patyshakuliyeva, Marcos Di Falco, Adrian Tsang, Ronald P. de Vries, Willem J. H. van Berkel, Mirjam A. Kabel
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Background The ascomycete fungus Podospora anserina has been appreciated for its targeted carbohydrate-active enzymatic arsenal. As a late colonizer of herbivorous dung, the fungus acts specifically on the more recalcitrant fraction of ligno
Externí odkaz:
https://doaj.org/article/f29427e7c49b4cc985e58a83735db2dd
Autor:
Francesca Zammarchi, Simon Chivers, Karin Havenith, Francois Bertelli, Balakumar Vijayakrishnan, Patrick H van Berkel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Regulatory T cells (Tregs) contribute to an immunosuppressive tumor microenvironment. They play an important role in the establishment and progression of tumors with high Tregs infiltration and present a major obstacle to tumor eradication
Externí odkaz:
https://doaj.org/article/200bc582c1964ab79fa9727162fd859e
Autor:
Matthias Frommhagen, Sumanth Kumar Mutte, Adrie H. Westphal, Martijn J. Koetsier, Sandra W. A. Hinz, Jaap Visser, Jean-Paul Vincken, Dolf Weijers, Willem J. H. van Berkel, Harry Gruppen, Mirjam A. Kabel
Publikováno v:
Biotechnology for Biofuels, Vol 10, Iss 1, Pp 1-16 (2017)
Abstract Background Many fungi boost the deconstruction of lignocellulosic plant biomass via oxidation using lytic polysaccharide monooxygenases (LPMOs). The application of LPMOs is expected to contribute to ecologically friendly conversion of biomas
Externí odkaz:
https://doaj.org/article/0e1052bbcf4f4ca58c78b9a580e39067
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/79f0aaac96c9472599da6b78f8bc0d51
Autor:
Adrie H. Westphal, Dirk Tischler, Florian Heinke, Sarah Hofmann, Janosch A. D. Gröning, Dirk Labudde, Willem J. H. van Berkel
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
p-Hydroxybenzoate hydroxylase (PHBH; EC 1.14.13.2) is a microbial group A flavoprotein monooxygenase that catalyzes the ortho-hydroxylation of 4-hydroxybenzoate to 3,4-dihydroxybenzoate with the stoichiometric consumption of NAD(P)H and oxygen. PHBH
Externí odkaz:
https://doaj.org/article/188737b94c7e433d9b94a2d55e125f81
Autor:
Anika Scholtissek, Eric Gädke, Caroline E. Paul, Adrie H. Westphal, Willem J. H. van Berkel, Dirk Tischler
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Class III old yellow enzymes (OYEs) contain a conserved cysteine in their active sites. To address the role of this cysteine in OYE-mediated asymmetric synthesis, we have studied the biocatalytic properties of OYERo2a from Rhodococcus opacus 1CP (WT)
Externí odkaz:
https://doaj.org/article/4a95a49b74ad46669d27dcc8e32f282d
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Lytic polysaccharide monooxygenases (LPMOs) are powerful enzymes that oxidatively cleave glycosidic bonds in polysaccharides. The ability of these copper enzymes to boost the degradation of lignocellulose has greatly stimulated research efforts and b
Externí odkaz:
https://doaj.org/article/98417c829c9f431cbf3409886bf9aa38