Zobrazeno 1 - 10
of 54
pro vyhledávání: '"P H, Seeburg"'
Autor:
David J. Sanderson, Aletheia Lee, Rolf Sprengel, Peter H. Seeburg, Paul J. Harrison, David M. Bannerman
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The GluA1 AMPAR subunit (encoded by the Gria1 gene) has been implicated in schizophrenia. Gria1 knockout in mice results in recently experienced stimuli acquiring aberrantly high salience. This suggests that GluA1 may be important for learni
Externí odkaz:
https://doaj.org/article/b9ce5fc089bb499b97f2ec2b7df45736
Autor:
Heinz Krestel, Simon Raffel, Marec von Lehe, Caroline Jagella, Susanna Moskau-Hartmann, Albert Becker, Christian E. Elger, Peter H. Seeburg, Arto Nirkko
Publikováno v:
Neurobiology of Disease, Vol 56, Iss , Pp 66-73 (2013)
To investigate whether alterations in RNA editing (an enzymatic base-specific change to the RNA sequence during primary transcript formation from DNA) of neurotransmitter receptor genes and of transmembrane ion channel genes play a role in human temp
Externí odkaz:
https://doaj.org/article/aebe8e72054945f2b28a25211080b340
Autor:
Florian Freudenberg, Verena Marx, Volker Mack, Liliana E. Layer, Matthias Klugmann, Peter H. Seeburg, Rolf Sprengel, Tansu Celikel
Publikováno v:
Neurobiology of Disease, Vol 52, Iss , Pp 160-167 (2013)
Glutamate receptor dependent synaptic plasticity plays an important role in the pathophysiology of depression. Hippocampal samples from clinically depressed patients display reduced mRNA levels for GluA1, a major subunit of AMPA receptors. Moreover,
Externí odkaz:
https://doaj.org/article/78b5cc7801db48129ad97384a88b8f67
Autor:
Yasuhito eWatanabe, Michaela K. Müller, Jakob evon Engelhardt, Rolf eSprengel, Peter H Seeburg, Hannah eMonyer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2016)
N-methyl-D-aspartate receptors (NMDARs) in all hippocampal areas play an essential role in distinct processes of memory formation as well as in sustaining cell survival of postnatally-generated neurons in the dentate gyrus (DG). In contrast to the be
Externí odkaz:
https://doaj.org/article/cf65631e29a44bf1bb15bb40892d9cef
Autor:
Ilona eObara, Scott eGoulding, Adam eGould, Kevin eLominac, Jia-Hua eHu, Ping Wu eZhang, Georg evon Jonquieres, Marlin eDehoff, Bo eXiao, Peter H Seeburg, Paul eWorley, Matthias eKlugmann, Karen K Szumlinski
Publikováno v:
Frontiers in Psychiatry, Vol 4 (2013)
Pain alters opioid reinforcement, via neuroadaptations within ascending pain pathways interacting with the limbic system. Nerve injury increases expression of glutamate receptors and Homer scaffolding proteins throughout the pain processing pathway a
Externí odkaz:
https://doaj.org/article/72361826b1e84747a6ec0b199841d0fd
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 5 (2012)
The GluA2 subunit in heteromeric AMPA receptor channels restricts Ca2+ permeability and block by polyamines, rendering linear the current-voltage relationship of these glutamate-gated cation channels. Although GluA2-lacking synaptic AMPA receptors oc
Externí odkaz:
https://doaj.org/article/3fa18582e0684ebf92a96362818ced62
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 4 (2011)
Externí odkaz:
https://doaj.org/article/78b51410c67a4065a5c335c8966bfbe6
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 2 (2009)
NMDA receptors are key molecules involved in physiological and pathophysiological brain processes such as plasticity and excitotoxicity. Neuronal activity regulates NMDA receptor levels in the cell membrane. However, little is known on which time sca
Externí odkaz:
https://doaj.org/article/43bc2e4696ed4809acfbe5131da06e96
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 2 (2009)
Neuronal migration is a key process in the developing and adult brain. Numerous factors act on intracellular cascades of migrating neurons and regulate the final position of neurons. One robust migration route persists postnatally – the rostral mig
Externí odkaz:
https://doaj.org/article/831da2ef6bca4777b4543cd2779b18de
Autor:
Peter H Seeburg
Publikováno v:
Frontiers in Neuroscience, Vol 2 (2008)
Externí odkaz:
https://doaj.org/article/56a1d25ad7f440dd927a5a526ecad6fc