Zobrazeno 1 - 10 of 19 pro vyhledávání: '"P H, Pouwels"'
2
Live bacterial delivery systems for development of mucosal vaccines
Autor: J E, Thole, P J, van Dalen, C E, Havenith, P H, Pouwels, J F, Seegers, F D, Tielen, M D, van der Zee, N D, Zegers, M, Shaw
Publikováno v: Current opinion in molecular therapeutics. 2(1)
By expression of foreign antigens in attenuated strains derived from bacterial pathogens and in non-pathogenic commensal bacteria, recombinant vaccines are being developed that aim to stimulate mucosal immunity. Recent advances in the pathogenesis an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::58c6e38445704d0dcf3b1b61a3797717
https://pubmed.ncbi.nlm.nih.gov/11249657
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3
Engineering the microflora to vaccinate the mucosa: serum immunoglobulin G responses and activated draining cervical lymph nodes following mucosal application of tetanus toxin fragment C-expressing lactobacilli
Autor: D M, Shaw, B, Gaerthé, R J, Leer, J G, Van Der Stap, C, Smittenaar, M, Heijne Den Bak-Glashouwer, J E, Thole, F J, Tielen, P H, Pouwels, C E, Havenith
Publikováno v: Immunology. 100(4)
The delivery of antigens to mucosal-associated lymphoid tissues in paediatric and immunocompromised populations by safe, non-invasive vectors, such as commensal lactobacilli, represents a crucial improvement to prevailing vaccination options. In this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::da04ce43ca17e111847c2d5abf1eaee2
https://pubmed.ncbi.nlm.nih.gov/10929079
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4
Molecular cloning and functional expression in lactobacillus plantarum 80 of xylT, encoding the D-xylose-H+ symporter of Lactobacillus brevis
Autor: S, Chaillou, Y C, Bor, C A, Batt, P W, Postma, P H, Pouwels
Publikováno v: Applied and environmental microbiology. 64(12)
A 3-kb region, located downstream of the Lactobacillus brevis xylA gene (encoding D-xylose isomerase), was cloned in Escherichia coli TG1. The sequence revealed two open reading frames which could code for the D-xylulose kinase gene (xylB) and anothe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::68721c113d9677f39a3477ff51d168ac
https://pubmed.ncbi.nlm.nih.gov/9835554
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5
Genetic engineering of lactobacilli, leuconostocs and Streptococcus thermophilus
Autor: P. H. Pouwels, A. Mercenier, B. M. Chassy
Publikováno v: Genetics and Biotechnology of Lactic Acid Bacteria ISBN: 9789401045841
Gasson, M.Vos, W.M. de, Genetics and biotechnology of lactic acid bacteria, 252-293
The lactic acid bacteria represent a large heterogeneous family of microorganisms that share the property of converting fermentable carbohydrates primarily to lactic acid. The homofermentative lactic acid bacteria convert one mole of glucose to two m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1401ab5249a5e590865f529c0cc355d9
https://doi.org/10.1007/978-94-011-1340-3_6
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6
Binding of tissue-type plasminogen activator to lysine, lysine analogs, and fibrin fragments
Autor: B. E. Enger-Valk, M. P. M. Caspers, G. A. W. De Munk, Jan H. Verheijen, P. H. Pouwels, G. T. G. Chang
Publikováno v: Biochemistry. 28:7318-7325
Human tissue-type plasminogen activator (t-PA) consists of five domains designated (starting from the N-terminus) finger, growth factor, kringle 1, kringle 2, and protease. The binding of t-PA to lysine-Sepharose and aminohexyl-Sepharose was found to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f4e7c083351d79890a03051271a226
https://doi.org/10.1021/bi00444a026
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7
Poliovirus Protein 3CD Is the Active Protease for Processing of the Precursor Protein P1 in vitro
Autor: B E Enger-Valk, B De Geus, R J Jackson, P H Pouwels, J Jore
Publikováno v: Journal of General Virology. 69:1627-1636
A transcription/translation system for generating poliovirus proteins in vitro has been used to assess the proteolytic activity of various polypeptides containing the virus-coded 3C region towards the poliovirus precursor protein P1. Plasmids contain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273b9b992ba925a7df5ab800f79844b0
https://doi.org/10.1099/0022-1317-69-7-1627
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9
Expression of the Escherichia coli trpE gene in E. coli K12 bacteria: Maximum level, rate and time of initiation of anthranilate synthetase production
Autor: C. Van Rotterdam, P. H. Pouwels, H. G. M. Hessing
Publikováno v: Molecular and General Genetics MGG. 210:256-261
We have investigated the effect of alterations in the structure of the plasmid-borne Escherichia coli tryptophan (trp) coding region and other regions of the same replicon on the level, rate and time of initiation of anthranilate synthetase component
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32027ca0103724986a5d3571d33972c
https://doi.org/10.1007/bf00325691
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10
Sensitivity to ultraviolet light of single- and double-stranded DNA
Autor: C. Van Rotterdam, H.S. Jansz, P. H. Pouwels
Publikováno v: Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects. 76:655-657
The ultraviolet sensitivity of ss-DNA and rf-DNA were studied using spheroplasts of E. coli K12S hcr/sup +/ and hcr/sup -/ strains, respectively. No difference in uv sensitivity was observed when ss-DNA was assayed either on hcr/ sup +/ or on hcr/sup
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37f4e49726342011a37971506aea28d9
https://doi.org/10.1016/0926-6550(63)90099-9
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