Methotrexate treatment hampers induction of vaccine-specific CD4 T cell responses in patients with IMID

Autor: Sander W Tas, Joep Killestein, Joost Raaphorst, Taco W Kuijpers, Alexandre E Voskuyl, Gertjan Wolbink, Theo Rispens, Anneke J van der Kooi, Anja Ten Brinke, Karina de Leeuw, Abraham Rutgers, Juan J Garcia-Vallejo, Frederike J Bemelman, YK Onno Teng, Phyllis I Spuls, Mark Löwenberg, Jelle de Wit, Diane van der Woude, Marcel W Bekkenk, Luuk Wieske, Esther Brusse, Laura Boekel, Filip Eftimov, Eileen W Stalman, Maurice Steenhuis, Sofie Keijzer, Olvi Cristianawati, Koos P J van Dam, Adriaan G Volkers, Annelie H Musters, Nicoline F Post, Angela L Bosma, Marc L Hilhorst, Yosta Vegting, Bo Broens, Barbara Horváth, Annabel M Ruiter, Matthias H Busch, Dirk Jan Hijnen, Niels J M Verstegen, Pieter A van Doorn, Jan JGM Verschuuren, Laura Y L Kummer, Ruth R Hagen, Christine Kreher, Lisan H Kuijper, Mariël C Duurland, Veronique A L Konijn, Carolien E van de Sandt, Laura Fernández Blanco, Amélie Bos, Charlotte Menage, Tineke Jorritsma, Jet van den Dijssel, Rivka de Jongh, Tom Ashhurst, Marit J van Gils, Mathieu Claireaux, Sija Marieke van Ham, Renée CF van Allaart, Adája E Baars, George Elias, Cécile ACM van Els, H Stephan Goedee, Geert RAM D’Haens, Papay BP Jallah, Elham S Mirfazeli, Jim BD Keijser, Lotte van Ouwerkerk, Pieter van Paassen, Agner R Parra Sanchez, W Ludo van der Pol, Corine RG Schreurs, R Bart Takkenberg, Koos AH Zwinderman

Publikováno v: RMD Open, Vol 10, Iss 4 (2024)

Objectives Methotrexate (MTX) is one of the most commonly used medications to treat rheumatoid arthritis (RA). However, the effect of MTX treatment on cellular immune responses remains incompletely understood. This raises concerns about the vulnerabi

Externí odkaz: https://doaj.org/article/afff65e4600e4deabe9d42545d2637c0

Two Cases of Q-Fever in Hairy Cell Leukemia

Autor: Emanuele Ammatuna, Emilio Iannitto, Lidwine W. Tick, Nicolaas L. A. Arents, Philip H. Kuijper, Marten R. Nijziel

Publikováno v: Case Reports in Hematology, Vol 2014 (2014)

Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative disorder accounting for about 2% of all leukemias. The clinical course is indolent, however HCL patients are particularly susceptible to infections. Here we report two cases of Q-fever as

Externí odkaz: https://doaj.org/article/b4b546a70cae46b2bddfb9fd3b0beac0

Platelet associated fibrinogen and ICAM-2 induce firm adhesion of neutrophils under flow conditions

Autor: P H, Kuijper, H I, Gallardo Tores, J W, Lammers, J J, Sixma, L, Koenderman, J J, Zwaginga

Publikováno v: Thrombosis and haemostasis. 80(3)

Surface-bound platelets support selectin-mediated rolling and beta2-integrin-mediated firm adhesion of neutrophils (PMN) under flow conditions. We examined which ligands on platelets mediate this firm adhesion. Surface-bound platelets express ICAM-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::591cb4001d7e5f1bbebfb9ebaace974a
https://pubmed.ncbi.nlm.nih.gov/9759625

Platelet and fibrin deposition at the damaged vessel wall: cooperative substrates for neutrophil adhesion under flow conditions

Autor: P H, Kuijper, H I, Gallardo Torres, J W, Lammers, J J, Sixma, L, Koenderman, J J, Zwaginga

Publikováno v: Blood. 89(1)

At sites of vessel wall damage, the primary hemostatic reaction involves platelet and fibrin deposition. At these sites, circulating leukocytes marginate and become activated. Adhered platelets can support leukocyte localization; however, the role of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3a43a3d545b962d1141210f8880d8640
https://pubmed.ncbi.nlm.nih.gov/8978289

Two Cases of Q-Fever in Hairy Cell Leukemia

Autor: Ammatuna, Emanuele, Iannitto, Emilio, W. Tick, Lidwine, L. A. Arents, Nicolaas, H. Kuijper, Philip, R. Nijziel, Marten

Publikováno v: Case Reports in Hematology; 2014, Vol. 2014 Issue: 1