Zobrazeno 1 - 10
of 111
pro vyhledávání: '"P H, Jacobs"'
Autor:
Elizabeth H. Jacobs, Jacquelyn Schatzman Raposo, Annarita Scardamaglia, Fowzan S. Alkuraya, Shahriar Nafissi, Henry Houlden, Stephan Zuchner, Mario A. Saporta
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103599- (2024)
Myotubularin-Related Protein 5 (MTMR5) is an inactive, poorly characterized D3-phosphatidylinositol phosphatase. Mutations in MTMR5 have been linked to Charcot-Marie-Tooth Disease Type 4B3 (CMT4B3), a rare, early-onset, recessive peripheral neuropath
Externí odkaz:
https://doaj.org/article/bbedd8f413e748e1972a41db4fc7773a
Autor:
José H. Jacobs, Maciej Strak, Guus J․M. Velders, Jelle Zorn, Lenny Hogerwerf, Mariana Simões, Suzanne Mijnen-Visser, Joost Wesseling, Miriam E. Gerlofs-Nijland, Lidwien A․M. Smit, Roel Vermeulen, Saskia van der Zee, Lapo Mughini-Gras, Massimo Stafoggia
Publikováno v:
Environmental Advances, Vol 17, Iss , Pp 100592- (2024)
This study aimed to examine acute effects of exposure to ambient air pollution on COVID-19 hospital admissions and mortality in the Netherlands. We hypothesized that exposure to increased air pollution in the preceding week might trigger an exacerbat
Externí odkaz:
https://doaj.org/article/bc49193f3bdf4e2e8662598c7be6fa5f
Autor:
Jennifer Kudelka, Malte Ollenschläger, Richard Dodel, Bjoern M. Eskofier, Markus A. Hobert, Klaus Jahn, Jochen Klucken, Bendix Labeit, M. Cristina Polidori, Tino Prell, Tobias Warnecke, Christine A. F. von Arnim, Walter Maetzler, Andreas H. Jacobs, for the DGG working group Neurology
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background The Comprehensive Geriatric Assessment (CGA) records geriatric syndromes in a standardized manner, allowing individualized treatment tailored to the patient’s needs and resources. Its use has shown a beneficial effect on the fun
Externí odkaz:
https://doaj.org/article/527af05bf2624a8e91e58b533806d719
Autor:
Scott A. Langenecker, Mindy Westlund Schreiner, Katie L. Bessette, Henrietta Roberts, Leah Thomas, Alina Dillahunt, Stephanie L. Pocius, Daniel A. Feldman, Dave Jago, Brian Farstead, Myah Pazdera, Erin Kaufman, Jennica A. Galloway, Patricia K. Kerig, Amanda Bakian, Robert C. Welsh, Rachel H. Jacobs, Sheila E. Crowell, Edward R. Watkins
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 1, Pp 1-10 (2024)
Background: Rumination-focused cognitive behavioral therapy (RF-CBT) is designed to reduce depressive rumination or the habitual tendency to dwell on experiences in a repetitive, negative, passive, and global manner. RF-CBT uses functional analysis,
Externí odkaz:
https://doaj.org/article/6873e1a4b11148018245415079f3c2b8
Autor:
Richard J. Nowak, Ari Breiner, Vera Bril, Jeffrey A. Allen, Shaida Khan, Todd Levine, Daniel H. Jacobs, Gregory Sahagian, Zaeem A. Siddiqi, Jing Xu, William L. Macias, Michael Benatar, ASCEND MG Study Group
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 1, Pp 194-206 (2024)
Abstract Objectives To assess the safety, tolerability, and key pharmacodynamic effects of subcutaneous batoclimab, a fully human anti‐neonatal Fc receptor monoclonal antibody, in patients with generalized myasthenia gravis and anti‐acetylcholine
Externí odkaz:
https://doaj.org/article/88f6f869acee42ffae3f50c106820b47
Autor:
Henrietta Roberts, Mindy Westlund Schreiner, Stephanie Pocius, Alina K. Dillahunt, Brian Farstead, Daniel Feldman, Katie L. Bessette, Erin A. Kaufman, Will Slattery, Rachel H. Jacobs, David Jago, Sheila E. Crowell, Edward R Watkins, Scott A. Langenecker
Publikováno v:
Journal of Affective Disorders Reports, Vol 16, Iss , Pp 100729- (2024)
Background: Trait rumination is a habitual response to negative experiences that can emerge during adolescence, increasing risk of depression. Trait rumination is correlated with poor inhibitory control (IC) and altered default mode network (DMN) and
Externí odkaz:
https://doaj.org/article/3a07def517c943089f70be2d5d7a3ab8
Autor:
Mark Monane, Kim G. Johnson, B. Joy Snider, Raymond S. Turner, Jonathan D. Drake, Demetrius M. Maraganore, James L. Bicksel, Daniel H. Jacobs, Julia L. Ortega, Joni Henderson, Yan Jiang, Shuguang Huang, Justine Coppinger, Ilana Fogelman, Tim West, Joel B. Braunstein
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 10, Pp 1738-1748 (2023)
Abstract Objective The objective of this study was to examine clinicians' patient selection and result interpretation of a clinically validated mass spectrometry test measuring amyloid beta and ApoE blood biomarkers combined with patient age (Precivi
Externí odkaz:
https://doaj.org/article/9e6f29e4a0734aeb87bf127a5a529315
Autor:
Alexander Gerhard, Richard Sharples, Tsepo Goerttler, Kathryn McDonald, Eszter Visi, Rainer Hinz, Federico Turkheimer, Isabel Lewzey, Karl Herholz, Andreas H. Jacobs, Clive Holmes
Publikováno v:
Exploration of Neuroscience, Vol 2, Iss 2, Pp 52-66 (2023)
Aim: Microglial activation is increasingly recognised as a factor in the progression of Alzheimer’s disease (AD) and may be modified by systemic inflammatory signals including serum tumour necrosis factor (TNF)-α. The aim was to investigate whethe
Externí odkaz:
https://doaj.org/article/8e7485364cb346a99bb854966d873498
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
The Pliocene shows that a warmer world can support both expanded and contracted marine Oxygen Minimum Zones. While oxygen distributions were overall like today, there was less low-oxygen water in the North Pacific and more in the North Atlantic
Externí odkaz:
https://doaj.org/article/55faae2705da4fb7b0fe44dbe47dcdb5
Autor:
Anna Malekkou, Athina Theodosiou, Angelos Alexandrou, Ioannis Papaevripidou, Carolina Sismani, Edwin H. Jacobs, George J.G. Ruijter, Violetta Anastasiadou, Sofia Ourani, Emilia Athanasiou, Anthi Drousiotou, Olga Grafakou, Petros P. Petrou
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 36, Iss , Pp 100997- (2023)
Pompe disease is a rare metabolic myopathy caused by pathogenic variants affecting the activity of the lysosomal glycogen-degrading enzyme acid alpha-glucosidase (GAA). Impaired GAA function results in the accumulation of undegraded glycogen within l
Externí odkaz:
https://doaj.org/article/1393d2d27d9e4b658ab162df0508fc9f