Zobrazeno 1 - 10 of 16 pro vyhledávání: '"P H, Elzer"'
1
Akademický článek
Buffalo, bush meat, and the zoonotic threat of brucellosis in Botswana.
Autor: Kathleen Anne Alexander, Jason Kenna Blackburn, Mark Eric Vandewalle, Risa Pesapane, Eddie Kekgonne Baipoledi, Phil H Elzer
Publikováno v: PLoS ONE, Vol 7, Iss 3, p e32842 (2012)
Brucellosis is a zoonotic disease of global importance infecting humans, domestic animals, and wildlife. Little is known about the epidemiology and persistence of brucellosis in wildlife in Southern Africa, particularly in Botswana.Archived wildlife
Externí odkaz: https://doaj.org/article/a343551c533845d0ba06ad8cb93824f8
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2
Protective immunity to Brucella ovis in BALB/c mice following recovery from primary infection or immunization with subcellular vaccines
Autor: C. M. Marin, P H Elzer, José M. Blasco, A J Winter, Carlos Gamazo, M.P. Jiménez de Bagüés
Publikováno v: Scopus-Elsevier
ResearcherID
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Experiments were performed with BALB/c mice to elucidate the roles of humoral and cell-mediated immune responses in the acquisition of protective immunity to Brucella ovis and to compare infection immunity with immunity developed through vaccination
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7692c86470a99c9910db066c87915d
https://doi.org/10.1128/iai.62.2.632-638.1994
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3
Improved solid-phase synthesis of alpha,alpha-dialkylated amino acid-rich peptides with antimicrobial activity
Autor: S R, Haynes, S D, Hagins, M M, Juban, P H, Elzer, R P, Hammer
Publikováno v: The journal of peptide research : official journal of the American Peptide Society. 66(6)
A homologous series of nonapeptides and their acetylated versions were successfully prepared using solid-phase synthetic techniques. Each nonapeptide was rich in alpha,alpha-dialkylated amino acids [one 4-aminopiperidine-4-carboxylic acid (Api) and s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1cb877fc0a45c43ebcfa7683fe6808d7
https://pubmed.ncbi.nlm.nih.gov/16316449
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4
Biosafety of Brucella abortus strain RB51 for vaccination of mature bulls and pregnant heifers
Autor: M D, Edmonds, G G, Schurig, L E, Samartino, P G, Hoyt, J V, Walker, S D, Hagius, P H, Elzer
Publikováno v: American journal of veterinary research. 60(6)
To determine shedding and colonization profiles in mature sexually intact bulls and pregnant heifers after vaccination with a standard calfhood dose of Brucella abortus strain RB51 (SRB51).6 sexually mature 3-year-old Jersey bulls and 7 mixed-breed h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a1b5a2cc940134fcafed7c1b725a3d7f
https://pubmed.ncbi.nlm.nih.gov/10376900
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5
Protection against infection and abortion induced by virulent challenge exposure after oral vaccination of cattle with Brucella abortus strain RB51
Autor: P H, Elzer, F M, Enright, L, Colby, S D, Hagius, J V, Walker, M B, Fatemi, J D, Kopec, V C, Beal, G G, Schurig
Publikováno v: American journal of veterinary research. 59(12)
To determine efficacy of orally administered Brucella abortus vaccine strain RB51 against virulent B abortus challenge exposure in cattle as a model for vaccination of wild ungulates.20 mixed-breed beef cattle obtained from a brucellosis-free herd.Se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ed5064879ce6c151c76f1c5ac67e8064
https://pubmed.ncbi.nlm.nih.gov/9858409
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6
Interleukin 2 promoter/enhancer controlled expression of a synthetic cecropin-class lytic peptide in transgenic mice and subsequent resistance to Brucella abortus
Autor: W A, Reed, P H, Elzer, F M, Enright, J M, Jaynes, J D, Morrey, K L, White
Publikováno v: Transgenic research. 6(5)
The addition of an antimicrobial that can be synthesized by the mammalian immune system at the point of challenge may enhance disease resistance. A possible group of agents are cecropins, broad-spectrum antimicrobial peptides, which have been describ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::978eb35d1dfca1498f3cb72df0371b4c
https://pubmed.ncbi.nlm.nih.gov/9322370
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7
Protection of BALB/c mice against homologous and heterologous species of Brucella by rough strain vaccines derived from Brucella melitensis and Brucella suis biovar 4
Autor: A J, Winter, G G, Schurig, S M, Boyle, N, Sriranganathan, J S, Bevins, F M, Enright, P H, Elzer, J D, Kopec
Publikováno v: American journal of veterinary research. 57(5)
To evaluate stable rough mutants derived from Brucella melitensis 16M and B suis 2579 (biovar 4) as vaccines against homologous and heterologous Brucella spp in the BALB/c mouse model. DESIGN, ANIMALS, AND PROCEDURE: Rough mutants VTRM1 and VTRS1 wer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::68ae09697b029222c71ba04fc51e2208
https://pubmed.ncbi.nlm.nih.gov/8723881
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8
A Brucella melitensis high temperature requirement A (htrA) deletion mutant demonstrates a stress response defective phenotype in vitro and transient attenuation in the BALB/c mouse model
Autor: R W, Phillips, P H, Elzer, I I, Roop RM
Publikováno v: Microbial pathogenesis. 19(5)
Bacterial stress response proteins of the high temperature requirement A (HtrA) family are serine proteases which appear to play an important role in scavenging oxidatively damaged proteins from the cell before they reach toxic levels. An isogenic ht
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d3c9252058288062a760e445c5638504
https://pubmed.ncbi.nlm.nih.gov/8778563
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10
Effects of gamma radiation and azathioprine on Brucella abortus infection in BALB/c mice
Autor: P H, Elzer, G E, Rowe, F M, Enright, A J, Winter
Publikováno v: American journal of veterinary research. 52(6)
Sublethal irradiation of BALB/c mice 4 hours prior to inoculation with 5 x 10(4) virulent Brucella abortus, caused significant (P less than 0.01) reductions in bacterial numbers in comparison with numbers in unirradiated controls. Numbers of brucella
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::86c3906d72fed807b9caec18beb30311
https://pubmed.ncbi.nlm.nih.gov/1909103
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