Zobrazeno 1 - 10
of 87
pro vyhledávání: '"P G Lucas"'
Autor:
Michael Chang, Mohamed Sherief, Maria Ioannou, Viveka Chinnasamy, Lucy Chen, Michael Frost, Michelle Mattson-Hoss, Herb Sarnoff, David O. Kamson, Matthias Holdhoff, Debraj Mukherjee, Chetan Bettegowda, Jordina Rincon-Torroella, Victoria Croog, Peng Huang, Fausto J. Rodriguez, Calixto-Hope G. Lucas, Karisa C. Schreck
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Background NF1 inactivation is associated with sensitivity to MEK inhibitor targeted therapy in low-grade and some high-grade gliomas. NF1 loss may also be a harbinger of exploitable vulnerabilities in IDH-wildtype glioblastoma (GBM). Accura
Externí odkaz:
https://doaj.org/article/750d716ba61347bc87ffa9e517a87e9c
MerlinS13 phosphorylation regulates meningioma Wnt signaling and magnetic resonance imaging features
Autor:
Charlotte D. Eaton, Lauro Avalos, S. John Liu, Zhenhong Chen, Naomi Zakimi, Tim Casey-Clyde, Paola Bisignano, Calixto-Hope G. Lucas, Erica Stevenson, Abrar Choudhury, Harish N. Vasudevan, Stephen T. Magill, Jacob S. Young, Nevan J. Krogan, Javier E. Villanueva-Meyer, Danielle L. Swaney, David R. Raleigh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Meningiomas are associated with inactivation of NF2/Merlin, but approximately one-third of meningiomas with favorable clinical outcomes retain Merlin expression. Biochemical mechanisms underlying Merlin-intact meningioma growth are incomplet
Externí odkaz:
https://doaj.org/article/09cad89a882942b286e00cb8af45c58a
Autor:
Zhichao Wu, Karen Dazelle, Zied Abdullaev, Hye-Jung Chung, Sonika Dahiya, Matthew Wood, Han Lee, Calixto-Hope G. Lucas, Qinwen Mao, Lorraina Robinson, Igor Fernandes, Matthew McCord, Peter Pytel, Kyle S. Conway, Rebecca Yoda, Jennifer M. Eschbacher, Ossama M. Maher, Martin Hasselblatt, Bret C. Mobley, Jack M. Raisanen, Kimmo J. Hatanpaa, Joshua Byers, Norman L. Lehman, Patrick J. Cimino, Drew Pratt, Martha Quezado, Kenneth Aldape
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-7 (2024)
Abstract Papillary tumor of the pineal region (PTPR) is an uncommon tumor of the pineal region with distinctive histopathologic and molecular characteristics. Experience is limited with respect to its molecular heterogeneity and clinical characterist
Externí odkaz:
https://doaj.org/article/ccb5b973f4b744df99cf76d1b717245c
Autor:
Sebastian G. Dalman, Mark A. Loewen, R. Alexander Pyron, Steven E. Jasinski, D. Edward Malinzak, Spencer G. Lucas, Anthony R. Fiorillo, Philip J. Currie, Nicholas R. Longrich
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Tyrannosaurid dinosaurs dominated as predators in the Late Cretaceous of Laurasia, culminating in the evolution of the giant Tyrannosaurus rex, both the last and largest tyrannosaurid. Where and when Tyrannosaurini (T. rex and kin) originate
Externí odkaz:
https://doaj.org/article/369162bf33644ef2a5c668a1d13ad4ae
Autor:
Harish N. Vasudevan, Emily Payne, Cyrille L. Delley, S. John Liu, Kanish Mirchia, Matthew J. Sale, Sydney Lastella, Maria Sacconi Nunez, Calixto-Hope G. Lucas, Charlotte D. Eaton, Tim Casey-Clyde, Stephen T. Magill, William C. Chen, Steve E. Braunstein, Arie Perry, Line Jacques, Alyssa T. Reddy, Melike Pekmezci, Adam R. Abate, Frank McCormick, David R. Raleigh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Schwann cell tumors are the most common cancers of the peripheral nervous system and can arise in patients with neurofibromatosis type-1 (NF-1) or neurofibromatosis type-2 (NF-2). Functional interactions between NF1 and NF2 and broader mecha
Externí odkaz:
https://doaj.org/article/a34dc09304394fd3ae1c29c108fd0bbd
Autor:
Lawrence H. Tanner, Spencer G. Lucas
Publikováno v:
The Depositional Record, Vol 9, Iss 4, Pp 1131-1152 (2023)
Abstract The mass extinction at the Cretaceous–Palaeogene boundary is widely attributed to sudden and severe climate changes forced by bolide impact and/or flood basalt volcanism. In terrestrial depositional settings, these changes may potentially
Externí odkaz:
https://doaj.org/article/471d9b3638194db79eb76b1b98fba1f6
Autor:
Spencer G. Lucas
Publikováno v:
Geosciences, Vol 14, Iss 9, p 246 (2024)
Two ichnofacies have been named to encompass inland eolian depositional systems, the Octopodichnus and the Entradichnus ichnofacies, and are often combined into a single, Octopodichnus–Entradichnus ichnofacies. In contrast, coastal dune fields are
Externí odkaz:
https://doaj.org/article/a9ca1a9234c04e189ce1b14ab7f0f166
Autor:
Meritxell Pallejà-Millán, Alba Hernández-Pinilla, Jose-Luis Clua-Espuny, Eva María Satué-Gracia, Francisco M Martín-Luján, A Panisello-Tafalla, J Clua-Queralt, A Grau-Roche, T Forcadell-Arenas, KV Yañez-Cabrera, E Muria-Subirats, EM Lloren-Insa, MJ Forcadell-Peris, G Batlle-Escolies, S Sancho-Maigi, T Miralles Saura, A Quilez-Recio, G Lucas-Noll, C Calduch-Noll, C de Diego-Cabanes, A Diaz-Vilarasau, D Ribas-Seguí, C Molins-Rojas, D Gentille-Lorente, I Lechuga Duran, M Guillen-Marzo, LA Anmad-Shihadeh, A Bardají-Ruiz, JA Izuel-Navarro, AM Viveros-Castaño, M Rovira-Beltran, E Salvado-Geli, A Samitier-Pastor, P Delgado-Martínez, A Penalba-Morenilla
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Background Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. Future estimations suggest an increase in global burden of AF greater than 60% by 2050. Numerous studies provide growing evidence that AF is not only associated with s
Externí odkaz:
https://doaj.org/article/e4620712159743b79551c5368ad12dfe
Autor:
Simon Valentin, Steven Kleinegesse, Neil R Bramley, Peggy Seriès, Michael U Gutmann, Christopher G Lucas
Publikováno v:
eLife, Vol 13 (2024)
Computational models are powerful tools for understanding human cognition and behavior. They let us express our theories clearly and precisely and offer predictions that can be subtle and often counter-intuitive. However, this same richness and abili
Externí odkaz:
https://doaj.org/article/789aedb26b3f4ed884d14ee6749e3593
Autor:
A. Giribono, D. Alesini, F. Cardelli, G. Di Raddo, L. Faillace, M. Ferrario, A. Gallo, A. Gizzi, S. Lauciani, A. Liedl, L. Pellegrino, L. Piersanti, C. Vaccarezza, A. Vannozzi, J. Scifo, L. Ficcadenti, G. Castorina, G. Pedrocchi, G. J. Silvi, T. G. Lucas
Publikováno v:
Physical Review Accelerators and Beams, Vol 26, Iss 8, p 083402 (2023)
C-band technology is emerging as an exciting innovative approach to the creation of compact new accelerators. Besides the possibility to sustain higher gradients and higher repetition rate operation at normal conducting temperature, it also allows on
Externí odkaz:
https://doaj.org/article/b298bde032734961afea6b5397fd41a2