Zobrazeno 1 - 10
of 25
pro vyhledávání: '"P G Killenberg"'
Autor:
R B Kirkpatrick, P G Killenberg
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 7, Pp 895-901 (1980)
Administration of large doses of estrogens has been shown to result in decreased conjugation and increased sulfation of bile acids as well as cholestasis. There have been no previous studies on the effects of low doses of estrogens on these parameter
Externí odkaz:
https://doaj.org/article/d56a6412fb5745beb337511d270e5108
Autor:
P G Killenberg
Publikováno v:
Journal of Lipid Research, Vol 19, Iss 1, Pp 24-31 (1978)
An improved method for assaying choloyl-CoA synthetase activity (E.C. 6.2.1.7) and two methods for specific measurement of bile acid-CoA:amino acid N-acyltransferase activity (E.C. 2.3.1) are described. The methods are shown to be reproducible, linea
Externí odkaz:
https://doaj.org/article/ca3f7508499a4a29ae2bcbe355958808
Autor:
P G Killenberg, D F Dukes
Publikováno v:
Journal of Lipid Research, Vol 17, Iss 5, Pp 451-455 (1976)
Synthesis of the coenzyme A derivatives of bile acids by the mixed anyhydride method results in a product that is contaminated by unreacted CoASH and bile acid. These compounds can be purified by Sephadex LH-20 chromatography. In each case, the purif
Externí odkaz:
https://doaj.org/article/4ecd59da9420455e8904ae01f63115a8
Effects of monosulfate esters of taurochenodeoxycholate on bile flow and biliary lipids in hamsters.
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 5, Pp 673-679 (1989)
The effect of the 3 alpha- and 7 alpha-monosulfate esters of taurochenodeoxycholate on bile flow and biliary lipids was compared to the effect of unsulfated taurochenodeoxycholate. Test bile salts were infused directly into the portal circulation thr
Externí odkaz:
https://doaj.org/article/b5545ff80bda4d54bdce4ef5381ce9d9
Autor:
P. J. Pockros, M. Tong, W. M. Lee, D. J. Van Leeuwen, E. B. Keeffe, K. Bala, P. G. Killenberg, R. T. Foust, H. J. Rosenblate, K. M. Payne, H. Fromm, H. R. Lesesne, M. Black, The Consensus Interferon Study Group
Publikováno v:
Journal of Viral Hepatitis. 5:271-276
We have investigated the relationship between serum alanine aminotransferase (ALT) and hepatitis C virus (HCV) RNA in the assessment of responses to interferon (IFN) therapy in chronic HCV infection. Data from 704 patients with HCV infection who were
Autor:
P G, Killenberg
Publikováno v:
Seminars in gastrointestinal disease. 11(2)
A by-product of increasing experience with patients infected with the hepatitis C virus is the awareness of a variety of extrahepatic syndromes that seem to be associated with HCV infection. Recent investigations into the relationship between the hep
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 248:G639-G642
The effect of estrogens and androgens on hepatic glycolithocholate sulfotransferase activity was studied in male rats. Significant increases in specific activity were noted following treatment of rats for 21 days with 17 beta-estradiol, 17 alpha-ethy
Autor:
J T Jordan, P G Killenberg
Publikováno v:
Journal of Biological Chemistry. 253:1005-1010
An in vitro study of bile acid-CoA:amino acid N-acyltransferase activity of rat liver was undertaken in order to determine whether separate amino acid-specific enzymes catalyzed the formation of glycine and taurine conjugates of bile acids as postula
Publikováno v:
Journal of Biological Chemistry. 255:10157-10159
Thin layer and high performance liquid chromatography identified the 3-monosulfate ester as the predominant product of in vitro enzymatic sulfation of glyco- and taurochenodeoxycholate by rat liver and kidney and hamster liver. The rate of synthesis
Autor:
P G, Killenberg, J T, Jordan
Publikováno v:
The Journal of biological chemistry. 253(4)
An in vitro study of bile acid-CoA:amino acid N-acyltransferase activity of rat liver was undertaken in order to determine whether separate amino acid-specific enzymes catalyzed the formation of glycine and taurine conjugates of bile acids as postula