Zobrazeno 1 - 10
of 171
pro vyhledávání: '"P G Holt"'
Autor:
P. Bielefeld, A. Martirosyan, S. Martín-Suárez, A. Apresyan, G. F. Meerhoff, F. Pestana, S. Poovathingal, N. Reijner, W. Koning, R. A. Clement, I. Van der Veen, E. M. Toledo, O. Polzer, I. Durá, S. Hovhannisyan, B. S. Nilges, A. Bogdoll, N. D. Kashikar, P. J. Lucassen, T. G. Belgard, J. M. Encinas, M. G. Holt, C. P. Fitzsimons
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Traumatic brain injury (TBI) can result in long-lasting changes in hippocampal function. The changes induced by TBI on the hippocampus contribute to cognitive deficits. The adult hippocampus harbors neural stem cells (NSCs) that generate neu
Externí odkaz:
https://doaj.org/article/0c2fb42524ac4acfa68febab4842131e
Autor:
Gladymar Pérez Chacón, Marie J Estcourt, James Totterdell, Julie A Marsh, Kirsten P Perrett, Dianne E Campbell, Nicholas Wood, Michael Gold, Claire S Waddington, Michael O' Sullivan, Sonia McAlister, Nigel Curtis, Mark Jones, Peter B McIntyre, Patrick G Holt, Peter C Richmond, Tom Snelling
Publikováno v:
PLoS Medicine, Vol 21, Iss 6, p e1004414 (2024)
BackgroundIn many countries, infant vaccination with acellular pertussis (aP) vaccines has replaced use of more reactogenic whole-cell pertussis (wP) vaccines. Based on immunological and epidemiological evidence, we hypothesised that substituting the
Externí odkaz:
https://doaj.org/article/be16c543f46c4cda82bd594d8fb17ff1
Autor:
Araks Martirosyan, Rizwan Ansari, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Razmik Aleksanyan, Silvia Hnatova, Suresh Poovathingal, Catherine Marneffe, Dietmar R. Thal, Andrew Kottick, Victor J. Hanson-Smith, Sebastian Guelfi, William Plumbly, T. Grant Belgard, Emmanouil Metzakopian, Matthew G. Holt
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-24 (2024)
Abstract Parkinson’s Disease (PD) is the second most common neurodegenerative disorder. The pathological hallmark of PD is loss of dopaminergic neurons and the presence of aggregated α-synuclein, primarily in the substantia nigra pars compacta (SN
Externí odkaz:
https://doaj.org/article/ac5a812e7fc64915b2e68e33cecdd4a4
Autor:
Alison G. Holt, Andrea Hussong, M. Gabriela Castro, Kelly Bossenbroek Fedoriw, Allison M. Schmidt, Amy Prentice, Orrin D. Ware
Publikováno v:
Tobacco Use Insights, Vol 17 (2024)
Tobacco use is associated with morbidity and mortality. Many individuals who present to treatment facilities with substance use disorders (SUDs) other than tobacco use disorder also smoke cigarettes or have a concomitant tobacco use disorder. Despite
Externí odkaz:
https://doaj.org/article/057ff544836d4deabc31990625444fa7
Autor:
Arti A. Singh, Frances M. Shapter, Anne Bernard, Deanne J. Whitworth, Marnie G. Holt, Philip S. Waller, Stephanie L. Bond
Publikováno v:
Animals, Vol 14, Iss 16, p 2335 (2024)
No single teaching strategy supports all learning styles in veterinary science students. To facilitate more convenient and flexible teaching, learning, and revision, an innovative online digital learning platform—VetCloud—was developed to provide
Externí odkaz:
https://doaj.org/article/1f30de732b4742cfbc338e251b61df7f
Autor:
Bilal Ahmad Khan, Humaira Khalid, Najma Siddiqi, Faiza Aslam, Rubab Ayesha, Medhia Afzal, Sukanya Rajan, Kavindu Appuhamy, Kamrun Nahar Koly, Maria Bryant, Richard I. G. Holt, Gerardo A. Zavala
Publikováno v:
Mental Health Science, Vol 1, Iss 1, Pp 10-22 (2023)
Abstract People with severe mental illness (SMI) have a higher prevalence of obesity as compared with the general population, however, there is mixed evidence about the prevalence of underweight. Thus, the aim of this study is to determine the pooled
Externí odkaz:
https://doaj.org/article/073af4bc2be44f9bb702c776737bfcc8
Autor:
Pierre Lemaitre, Samar HK Tareen, Emanuela Pasciuto, Loriana Mascali, Araks Martirosyan, Zsuzsanna Callaerts‐Vegh, Suresh Poovathingal, James Dooley, Matthew G Holt, Lidia Yshii, Adrian Liston
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-18 (2023)
Abstract Cognitive decline is a common pathological outcome during aging, with an ill‐defined molecular and cellular basis. In recent years, the concept of inflammaging, defined as a low‐grade inflammation increasing with age, has emerged. Infilt
Externí odkaz:
https://doaj.org/article/78934a3a099a43c781c47882cc383255
Autor:
Araks Martirosyan, Rizwan Ansari, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Razmik Aleksanyan, Silvia Hnatova, Suresh Poovathingal, Catherine Marneffe, Dietmar R. Thal, Andrew Kottick, Victor J. Hanson-Smith, Sebastian Guelfi, William Plumbly, T. Grant Belgard, Emmanouil Metzakopian, Matthew G. Holt
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5bf4088beae54ac38e53d043a1ffdfc6
Autor:
Adrian M Davies, Alan G Holt
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 7, Pp 1435-1436 (2024)
Externí odkaz:
https://doaj.org/article/f652f816437a445ab48d02e07f7a8b44
Autor:
Marika Marino, Lujia Zhou, Melvin Y Rincon, Zsuzsanna Callaerts‐Vegh, Jens Verhaert, Jérôme Wahis, Eline Creemers, Lidia Yshii, Keimpe Wierda, Takashi Saito, Catherine Marneffe, Iryna Voytyuk, Yessica Wouters, Maarten Dewilde, Sandra I Duqué, Cécile Vincke, Yona Levites, Todd E Golde, Takaomi C Saido, Serge Muyldermans, Adrian Liston, Bart De Strooper, Matthew G Holt
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 4, Pp 1-21 (2022)
Abstract Single domain antibodies (VHHs) are potentially disruptive therapeutics, with important biological value for treatment of several diseases, including neurological disorders. However, VHHs have not been widely used in the central nervous syst
Externí odkaz:
https://doaj.org/article/10d3c6ff5fb2440ca2d3a9bf9989e4aa