Zobrazeno 1 - 10
of 23
pro vyhledávání: '"P G Heyworth"'
Autor:
Cristina M Tato, Barbara Joyce-Shaikh, Antara Banerjee, Yi Chen, Manjiri Sathe, Sarah E Ewald, Man-Ru Liu, Daniel Gorman, Terrill K McClanahan, Joseph H Phillips, Paul G Heyworth, Daniel J Cua
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31680 (2012)
Paired immunoglobulin-like receptors beta, PILRβ, and alpha, PILRα, are related to the Siglec family of receptors and are expressed primarily on cells of the myeloid lineage. PILRβ is a DAP12 binding partner expressed on both human and mouse myelo
Externí odkaz:
https://doaj.org/article/7dd2bc5d727840dcb49554716f36855f
Autor:
J G Meingassner, P G Heyworth
Although the human alimentary and urogenital tracts are parasitized by seven species of flagellate protozoa [115], only two, Giardia lamblia and Trichomonas vaginalis, are generally considered to be pathogens. This review, therefore, concentrates on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea29faaba702002220709d79ff438c7a
https://doi.org/10.1159/000398097
https://doi.org/10.1159/000398097
Publikováno v:
Blood Cells, Molecules, and Diseases. 27:16-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07534c4f7d245fb052a61cf8b7307a1
https://doi.org/10.1006/bcmd.2000.0347
https://doi.org/10.1006/bcmd.2000.0347
Autor:
C J Vlahos, W F Matter, R F Brown, A E Traynor-Kaplan, P G Heyworth, E R Prossnitz, R D Ye, P Marder, J A Schelm, K J Rothfuss
Publikováno v:
The Journal of Immunology. 154:2413-2422
Neutrophils contain a multicomponent NADPH oxidase system that is involved in the production of microbicidal oxidants. Stimulation of human neutrophils with the peptide FMLP activates this respiratory burst enzyme to produce superoxide and also has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d020dbf6198149d7d262636b637139a8
https://doi.org/10.4049/jimmunol.154.5.2413
https://doi.org/10.4049/jimmunol.154.5.2413
Publikováno v:
Scopus-Elsevier
Okadaic acid, a potent inhibitor of protein phosphatases 1 and 2A, profoundly influenced the activity of the NADPH oxidase of human neutrophils. It strongly inhibited stimulation of superoxide generation by phorbol 12-myristate 13-acetate (PMA) and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0b17cf851edfe91d2290861a6aa6b8
https://doi.org/10.1042/bj2860687
https://doi.org/10.1042/bj2860687
Publikováno v:
Blood. 96(3)
Chronic granulomatous disease is a rare inherited disorder caused by nonexistent or severely decreased phagocyte superoxide production that results in a severe defect in host defense and consequent predisposition to microbial infection. The enzyme re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9cb1a07c3dc915a4dcba7954e6f2e48e
https://pubmed.ncbi.nlm.nih.gov/10910929
https://pubmed.ncbi.nlm.nih.gov/10910929
Publikováno v:
The Journal of biological chemistry. 274(32)
The superoxide-generating neutrophil NADPH oxidase can be activated in cell-free reconstitution systems by several agonists, most notably arachidonic acid and the detergent sodium dodecyl sulfate. In this study, we show that both phosphatidic acids a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2cc7358f808e966557cb7f8b0655dfa
https://pubmed.ncbi.nlm.nih.gov/10428791
https://pubmed.ncbi.nlm.nih.gov/10428791
Publikováno v:
Blood. 87(10)
Neutrophils are known to contain a major 67-kD protein that undergoes enhanced phosphorylation and translocation to the membrane during cell stimulation. Recent studies have assumed that this 67-kD phosphoprotein is the 67-kD subunit of the phagocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4db867bc140e934c724c83fbd5795958
https://pubmed.ncbi.nlm.nih.gov/8639802
https://pubmed.ncbi.nlm.nih.gov/8639802
Publikováno v:
The Journal of biological chemistry. 269(49)
When the neutrophil NADPH oxidase is activated to generate superoxide, the cytosolic components, p47phox, p67phox, and the GTP-binding protein Rac, become stably associated with the plasma membrane. The translocation of p47phox and p67phox is depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50cf057caadea6846d9dfcecc3b4cc5f
https://pubmed.ncbi.nlm.nih.gov/7982999
https://pubmed.ncbi.nlm.nih.gov/7982999
Publikováno v:
Advances in experimental medicine and biology. 314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8a4525f4090dbdbded058680ba29924
https://pubmed.ncbi.nlm.nih.gov/1667963
https://pubmed.ncbi.nlm.nih.gov/1667963