Zobrazeno 1 - 10
of 14
pro vyhledávání: '"P G, Vekilov"'
Autor:
Manasa Yerragunta, Akash Tiwari, Rajshree Chakrabarti, Jeffrey D. Rimer, Bart Kahr, Peter G. Vekilov
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Organic solvents host the synthesis of high-value crystals used as pharmaceuticals and optical devices, among other applications. A knowledge gap persists on how replacing the hydrogen bonds and polar attraction that dominate aqueous environ
Externí odkaz:
https://doaj.org/article/6187e56e62f74fe7aef02aa48739a4ac
Autor:
Wenchuan Ma, Victoria A. Balta, Weichun Pan, Jeffrey D. Rimer, David J. Sullivan, Peter G. Vekilov
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Hematin crystallization is an essential element of heme detoxification of malaria parasites and its inhibition by antimalarial drugs is a common treatment avenue. We demonstrate at biomimetic conditions in vitro irreversible inhibition of he
Externí odkaz:
https://doaj.org/article/013c74089e25421ba8cc3c69aecca794
Autor:
Xianwei Sun, Praveen Kumar Chintakunta, Andrew A. Badachhape, Rohan Bhavane, Huan‐Jui Lee, David S. Yang, Zbigniew Starosolski, Ketan B. Ghaghada, Peter G. Vekilov, Ananth V. Annapragada, Eric A. Tanifum
Publikováno v:
Advanced Science, Vol 10, Iss 10, Pp n/a-n/a (2023)
Abstract The first line of treatment for most solid tumors is surgical resection of the primary tumor with adequate negative margins. Incomplete tumor resections with positive margins account for over 75% of local recurrences and the development of d
Externí odkaz:
https://doaj.org/article/1c952bbb3dd849fdb0cdfd5d02ed59e3
Autor:
Mohammad S. Safari, Zhiqing Wang, Kunaal Tailor, Anatoly B. Kolomeisky, Jacinta C. Conrad, Peter G. Vekilov
Publikováno v:
iScience, Vol 12, Iss , Pp 342-355 (2019)
Summary: About half of human cancers are associated with mutations of the tumor suppressor p53. Gained oncogenic functions of the mutants have been related to aggregation behaviors of wild-type and mutant p53. The thermodynamic and kinetic mechanisms
Externí odkaz:
https://doaj.org/article/2115390650724f12a24b2194be1d87df
Publikováno v:
Crystals, Vol 11, Iss 7, p 738 (2021)
One of the most consequential assumptions of the classical theories of crystal nucleation and growth is the Szilard postulate, which states that molecules from a supersaturated phase join a nucleus or a growing crystal individually. In the last 20 ye
Externí odkaz:
https://doaj.org/article/4dadaf865b1d4b88aee423215d9a8308
Publikováno v:
Proteins. 43(4)
We apply in situ atomic force microscopy to the crystallization of ferritins from solutions containing approximately 5% (w/w) of their inherent molecular dimers. Molecular resolution imaging shows that the dimers consist of two bound monomers. The co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a5de767591c98c9cec0cb127baa1460
https://pubmed.ncbi.nlm.nih.gov/11340651
https://pubmed.ncbi.nlm.nih.gov/11340651
Publikováno v:
Proteins. 42(1)
CC individuals, homozygous for the expression of beta(C)-globin, and SC individuals expressing both beta(S) and beta(C)-globins, are known to form intraerythrocytic oxy hemoglobin tetragonal crystals with pathophysiologies specific to the phenotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca67efc3014d15e54008ae5016d4de9f
https://pubmed.ncbi.nlm.nih.gov/11093264
https://pubmed.ncbi.nlm.nih.gov/11093264
Publikováno v:
Journal of molecular biology. 303(5)
The self-assembly of apoferritin molecules into crystals is a suitable model for protein crystallization and aggregation; these processes underlie several biological and biomedical phenomena, as well as for protein and virus self-assembly. We use the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7e633599d4796c1b63b5d5bec6252f7
https://pubmed.ncbi.nlm.nih.gov/11061967
https://pubmed.ncbi.nlm.nih.gov/11061967
Publikováno v:
Crystal Growth & Design; Nov2015, Vol. 15 Issue 11, p5535-5542, 8p
Publikováno v:
Journal of Physical Chemistry B; Jun2010, Vol. 114 Issue 22, p7620-7630, 11p