Zobrazeno 1 - 10
of 30
pro vyhledávání: '"P G, Tepper"'
Autor:
Pengfei Xu, Joy C. Yang, Bo Chen, Shu Ning, Xiong Zhang, Leyi Wang, Christopher Nip, Yuqiu Shen, Oleta T. Johnson, Gabriela Grigorean, Brett Phinney, Liangren Liu, Qiang Wei, Eva Corey, Clifford G. Tepper, Hong-Wu Chen, Christopher P. Evans, Marc A. Dall’Era, Allen C. Gao, Jason E. Gestwicki, Chengfei Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract N-Myc is a key driver of neuroblastoma and neuroendocrine prostate cancer (NEPC). One potential way to circumvent the challenge of undruggable N-Myc is to target the protein homeostasis (proteostasis) system that maintains N-Myc levels. Here
Externí odkaz:
https://doaj.org/article/7245d627558b40309015d3fca64f4865
Autor:
Tala Al-Saghir, MD, Jamie Hall, MD, Michael Diffley, MD, Amy Tang, PhD, Abigail Teitelbaum, MD, Donna G. Tepper, MD, Vigen Darian, MD, Maristella Evangelista, MD, Dunya Atisha, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 8, p e6082 (2024)
Background:. Studies have shown that chronic marijuana use is associated with increased vascular inflammation, endothelial damage, myocardial infarctions, strokes, arteritis, and cardiomyopathies; however, cannabis’s effect on wound healing in imme
Externí odkaz:
https://doaj.org/article/8e3bbd9871b0402188505aca2184d5d1
Autor:
Chun-Lung Chiu, Shiao-Ya Hong, Ying Tan, Yuh-Ru Julie Lee, Yi-Ping Shih, Clifford G. Tepper, Su Hao Lo
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 643-646 (2023)
Externí odkaz:
https://doaj.org/article/7310289ff01f4a5c9fbb5f4672340fcb
Autor:
Tomoki Inagaki, Kang-Hsin Wang, Ashish Kumar, Chie Izumiya, Hiroki Miura, Somayeh Komaki, Ryan R Davis, Clifford G Tepper, Harutaka Katano, Michiko Shimoda, Yoshihiro Izumiya
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011771 (2023)
Kaposi sarcoma-associated herpesvirus (KSHV) inflammatory cytokine syndrome (KICS) is a newly described chronic inflammatory disease condition caused by KSHV infection and is characterized by high KSHV viral load and sustained elevations of serum KSH
Externí odkaz:
https://doaj.org/article/db0380c7828a4eac8537464fb3507f31
Autor:
Michiko Shimoda, Tomoki Inagaki, Ryan R Davis, Alexander Merleev, Clifford G Tepper, Emanual Maverakis, Yoshihiro Izumiya
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011703 (2023)
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic double-stranded DNA virus and the etiologic agent of Kaposi's sarcoma and hyperinflammatory lymphoproliferative disorders. Understanding the mechanism by which KSHV increases the infected
Externí odkaz:
https://doaj.org/article/7d4872c8ed57458a9aebba3bd44da5bb
Autor:
Guiyan Yang, Prasant K. Jena, Ying Hu, Lili Sheng, Shin-Yu Chen, Carolyn M. Slupsky, Ryan Davis, Clifford G. Tepper, Yu-Jui Yvonne Wan
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Background Aging and diet are risks for metabolic diseases. Bile acid receptor farnesoid X receptor (FXR) knockout (KO) mice develop metabolic liver diseases that progress into cancer as they age, which is accelerated by Western diet (WD) in
Externí odkaz:
https://doaj.org/article/892d84c93f6c443d9942c868c6d8197d
Autor:
Kimberley D. Katleba, Maria-Malvina Tsamouri, Maitreyee Jathal, Han Bit Baek, Rebecca B. Armenta, Clifford G. Tepper, Gino Cortopassi, Paramita M. Ghosh, Maria Mudryj
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The observed sex disparity in bladder cancer (BlCa) argues that androgen receptor (AR) signaling has a role in these malignancies. BlCas express full-length AR (FL-AR), constitutively active AR splice variants, including AR-v19, or both, and
Externí odkaz:
https://doaj.org/article/808e9dbfa3f84e6190abe7c760f86466
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291766 (2023)
Tissue engineering has driven significant research in the strive to create a supply of tissues for patient treatment. Cell integration into engineered tissues maximizes functional capabilities, however, issues of rejection remain. Autologous cell sou
Externí odkaz:
https://doaj.org/article/f98bd23e1897430c9f5bf50d94e34adc
Autor:
Michiko Shimoda, Yuanzhi Lyu, Kang-Hsin Wang, Ashish Kumar, Hiroki Miura, Joshua F. Meckler, Ryan R. Davis, Chanikarn Chantarasrivong, Chie Izumiya, Clifford G. Tepper, Ken-ichi Nakajima, Joseph Tuscano, Gustavo Barisone, Yoshihiro Izumiya
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Shimoda et al. present evidence that a small functional peptide derived from the KSHV transactivator could be used to target MYC in cancer. The authors find that the peptide attenuates MYC expression, reduces cell proliferation, and selectively kills
Externí odkaz:
https://doaj.org/article/eaec3f23d40d4e7a83a5c5ddca22da0a
Autor:
Alex Q. Lee, Hiroaki Konishi, Connie Duong, Sakiko Yoshida, Ryan R. Davis, Jonathan E. Van Dyke, Masami Ijiri, Bridget McLaughlin, Kyoungmi Kim, Yueju Li, Laurel Beckett, Nitin Nitin, John D. McPherson, Clifford G. Tepper, Noriko Satake
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In leukemia, a distinct subpopulation of cancer-initiating cells called leukemia stem cells (LSCs) is believed to drive population expansion and tumor growth. Failing to eliminate LSCs may result in disease relapse regardless of the amount of non-LSC
Externí odkaz:
https://doaj.org/article/65345325b8c3492586a08bddfb989d5c