Zobrazeno 1 - 10
of 37
pro vyhledávání: '"P G, Strange"'
Autor:
Anton Lund, Mette B. Damholt, Ditte G. Strange, Jesper Kelsen, Hasse Møller-Sørensen, Kirsten Møller
Publikováno v:
Case Reports in Critical Care, Vol 2017 (2017)
Dialysis disequilibrium syndrome (DDS) is a serious neurological complication of hemodialysis, and patients with acute brain injury are at increased risk. We report a case of DDS leading to intracranial hypertension in a patient with anoxic brain inj
Externí odkaz:
https://doaj.org/article/2cd064f45570487a9c26d4feca563c91
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158808 (2016)
Many G protein-coupled receptors have been shown to be sensitive to the presence of sodium ions (Na+). Using radioligand competition binding assays, we have examined and compared the effects of sodium ions on the binding affinities of a number of str
Externí odkaz:
https://doaj.org/article/d4fa5368b2c742dda2722e9410ca87e0
Publikováno v:
Scopus-Elsevier
The human 5-hydroxytryptamine 5-HT1A receptor gene was transfected into Chinese hamster ovary cells. A series of recombinant monoclonal cell lines expressing the receptor were isolated and the properties of one cell line that expressed receptors at a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8155eae400d82cea06d611b4ee2d7ab
https://doi.org/10.1042/bj2850933
https://doi.org/10.1042/bj2850933
Publikováno v:
British journal of pharmacology. 151(1)
The aim of this report is to study mechanisms of G protein activation by agonists.The association and dissociation of guanosine 5'-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPgammaS) binding at G proteins in membranes of CHO cells stably transfected wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::353bb975ac3340c444ca8c06770e9bf3
https://pubmed.ncbi.nlm.nih.gov/17351658
https://pubmed.ncbi.nlm.nih.gov/17351658
Publikováno v:
The Journal of biological chemistry. 276(31)
The D(2) dopamine receptor has been expressed in Sf21 insect cells together with the G proteins G(o) and G(i2), using the baculovirus system. Expression levels of receptor and G protein (alpha, beta, and gamma subunits) in the two preparations were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::abd06249700a669a3ff938c5b8e25155
https://pubmed.ncbi.nlm.nih.gov/11369753
https://pubmed.ncbi.nlm.nih.gov/11369753
Publikováno v:
Journal of neurochemistry. 77(2)
The antipsychotic drugs have been shown to be inverse agonists at the D(2) dopamine receptor. We have examined the mechanism of this inverse agonism by making mutations in residue T343 in the base of the sixth transmembrane spanning region of the rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a0b464255af607a432d2ce4ffe34935
https://pubmed.ncbi.nlm.nih.gov/11299312
https://pubmed.ncbi.nlm.nih.gov/11299312
Autor:
D, Armstrong, P G, Strange
Publikováno v:
The Journal of biological chemistry. 276(25)
We have examined the binding of two radioligands ([(3)H]spiperone and [(3)H]raclopride) to D(2) dopamine receptors expressed in Chinese hamster ovary cells. In saturation binding experiments in the presence of sodium ions, both radioligands labeled a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4967af82359c75ad1c05212732fc485
https://pubmed.ncbi.nlm.nih.gov/11278324
https://pubmed.ncbi.nlm.nih.gov/11278324
Autor:
P G, Strange
Publikováno v:
Pharmacological reviews. 53(1)
Interaction of the antipsychotic drugs with dopamine receptors of the D2, D3, or D4 subclasses is thought to be important for their mechanisms of action. Consideration of carefully defined affinities of the drugs for these three receptors suggests th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4bb4b885d630e3963cfbc208b223687
https://pubmed.ncbi.nlm.nih.gov/11171942
https://pubmed.ncbi.nlm.nih.gov/11171942
Autor:
P G, Strange
Publikováno v:
Biochemical pharmacology. 58(7)
Activation of G-protein coupled receptors by agonists is thought to involve the stabilisation of a ternary complex of agonist/receptor/G-protein, leading to effector activation, but this mechanism may be an oversimplification, as follows: (a) Agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a602ce052b9525d02931fd6f70337009
https://pubmed.ncbi.nlm.nih.gov/10484065
https://pubmed.ncbi.nlm.nih.gov/10484065
Publikováno v:
Biotechnology and bioengineering. 63(5)
In this study we compare intracellular transport and processing of a recombinant glycoprotein in mammalian and insect cells. Detailed analysis of the N-glycosylation of recombinant human IFN-gamma by matrix-assisted laser-desorption mass spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf4d8f25ffe94005a976ba324856a54c
https://pubmed.ncbi.nlm.nih.gov/10397812
https://pubmed.ncbi.nlm.nih.gov/10397812