Výsledky vyhledávání - "P G, Prokocimer"

Akademický článek

Efficacy, safety, tolerability and population pharmacokinetics of tedizolid, a novel antibiotic, in Latino patients with acute bacterial skin and skin structure infections

Autor: Alejandro Ortiz-Covarrubias, Edward Fang, Philippe G. Prokocimer, Shawn D. Flanagan, Xu Zhu, Jose Francisco Cabré-Márquez, Toshiaki Tanaka, Julie Passarell, Jill Fiedler-Kelly, Esteban C. Nannini

Publikováno v: Brazilian Journal of Infectious Diseases, Vol 20, Iss 2, Pp 184-192 (2016)

Acute bacterial skin and skin structure infections are caused mainly by Gram-positive bacteria which are often treated with intravenous vancomycin, daptomycin, or linezolid, with potential step down to oral linezolid for outpatients. Tedizolid phosph

Externí odkaz: https://doaj.org/article/937add2603ef4647aeb42508bf03118d

Zobrazit plný text záznamu

Aminophylline shortens thiopental sleep-time and enhances noradrenergic neurotransmission in rats

Autor: Mervyn Maze, Ethan A. Nicholls, P. G. Prokocimer, Gina L. Louie

Publikováno v: Brain Research. 383:377-381

We investigated the effect of aminophylline on thiopental sleep-times and monoamine neurotransmitter turnover rates in discrete brain areas. Aminophylline-treated rats had shorter thiopental sleep-times than saline-treated controls. Noradrenergic neu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb13091b5397065a7db57e72733b2c43
https://doi.org/10.1016/0006-8993(86)90044-2

Zobrazit plný text záznamu

Mechanism for desensitization of beta-adrenergic receptor-stimulated lipolysis in adipocytes from rats harboring pheochromocytoma

Autor: P. G. Prokocimer, Ross G. Vickery, Mervyn Maze, Brian B. Hoffman

Publikováno v: Endocrinology. 123(1)

Prolonged stimulation of beta-adrenergic receptors with catecholamines leads to desensitization of their ability to activate cAMP accumulation. However, little is known about the relationship between these changes and possible alterations in physiolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acec9ca452c5a1b71f33b0d327612a8a
https://pubmed.ncbi.nlm.nih.gov/2838264

Zobrazit plný text záznamu

Cellular tolerance to adenosine receptor-mediated inhibition of lipolysis: altered adenosine 3',5'-monophosphate metabolism and protein kinase activation

Autor: Gerald M. Reaven, Brian B. Hoffman, Randall H. Vagelos, H. Chang, John M. Thomas, P. G. Prokocimer

Publikováno v: Endocrinology. 124(5)

Prolonged exposure of many types of cells to drugs or hormones that inhibit the activity of the enzyme adenylate cyclase, such as narcotics and alpha 2-adrenergic agonists, leads to enhanced accumulation of cAMP upon removal of the inhibitory drug. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70dd22886fe692705c457eed34edf050
https://pubmed.ncbi.nlm.nih.gov/2539980

Zobrazit plný text záznamu

Halothane anesthetic requirements are not affected by aminophylline treatment in rats and dogs

Autor: Gina L. Louie, Mervyn Maze, Ethan A. Nicholls, P. G. Prokocimer

Publikováno v: Anesthesiology. 65(6)

The authors determined the effects of aminophylline on the anesthetic requirements for halothane in rats and dogs. MAC for halothane was determined in rats (n = 24) before and after aminophylline, 100 mg X kg-1 ip, or an equal volume of saline. Becau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0f537662e61a07412f83d1a53de61a
https://pubmed.ncbi.nlm.nih.gov/3789436

Zobrazit plný text záznamu

Mechanism of halothane-induced inhibition of isoproterenol-stimulated lipolysis in isolated rat adipocytes

Autor: P G, Prokocimer, M, Maze, R G, Vickery, F B, Kraemer, R, Gandjei, B B, Hoffman

Publikováno v: Molecular pharmacology. 33(3)

The effect of halothane on isoproterenol-stimulated lipolysis was determined in isolated rat epididymal fat cells. The maximal lipolytic response (Emax) activated by isoproterenol was 350 +/- 61 nmol of glycerol/10(5) cells/hr with an EC50 of 5.1 X 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::028b39ec5327d251827f824c2d61a72d
https://pubmed.ncbi.nlm.nih.gov/3352597

Zobrazit plný text záznamu

Role of the sympathetic nervous system in the maintenance of hypertension in rats harboring pheochromocytoma

Autor: P G, Prokocimer, M, Maze, B B, Hoffman

Publikováno v: The Journal of pharmacology and experimental therapeutics. 241(3)

Hypertension due to pheochromocytoma is generally considered to be a straightforward, direct consequence of the elevated concentrations of circulating catecholamines. However, clonidine, a centrally acting antihypertensive drug, has been reported to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eb89da1442d83742240c4bad83f89175
https://pubmed.ncbi.nlm.nih.gov/3598906

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání