Zobrazeno 1 - 10
of 12
pro vyhledávání: '"P G, Mermelstein"'
Autor:
Andrew D. Chapp, Chinonso A. Nwakama, Pramit P. Jagtap, Chau-Mi H. Phan, Mark J. Thomas, Paul G. Mermelstein
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 3, Pp 100295- (2024)
Background: Cocaine-induced plasticity in the nucleus accumbens shell of males occurs primarily in dopamine D1 receptor–expressing medium spiny neurons (D1R-MSNs), with little if any impact on dopamine D2 receptor–expressing medium spiny neurons
Externí odkaz:
https://doaj.org/article/fa18c96506214df9aac4862f83a34dad
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Background The nucleus accumbens (NAc) is an important region in motivation and reward. Glutamatergic inputs from the infralimbic cortex (ILC) to the shell region of the NAc (NAcSh) have been implicated in driving the motivation to seek rewa
Externí odkaz:
https://doaj.org/article/9e178a035dab4cf3aae934eb977cadb8
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Estrogen receptors were initially identified in the uterus, and later throughout the brain and body as intracellular, ligand-regulated transcription factors that affect genomic change upon ligand binding. However, rapid estrogen receptor signaling in
Externí odkaz:
https://doaj.org/article/040bbe3b698c444db99e7bcb0ff5aebb
Autor:
Johnathan M. Borland, Ellen Kim, Samuel P. Swanson, Patrick E. Rothwell, Paul G. Mermelstein, Robert L. Meisel
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Our social relationships determine our health and well-being. In rodent models, there is now strong support for the rewarding properties of aggressive or assertive behaviors to be critical for the expression and development of adaptive social relatio
Externí odkaz:
https://doaj.org/article/59c62afed32d4a7f922c73ee49102036
Autor:
Maxwell T. Finkelstein, Adam G. Mermelstein, Emma Parker Miller, Paul C. Seth, Erik-Stephane D. Stancofski, Daniela Fera
Publikováno v:
Viruses, Vol 13, Iss 1, p 134 (2021)
Coronavirus research has gained tremendous attention because of the COVID-19 pandemic, caused by the novel severe acute respiratory syndrome coronavirus (nCoV or SARS-CoV-2). In this review, we highlight recent studies that provide atomic-resolution
Externí odkaz:
https://doaj.org/article/c5c27bfe5b7743df8ccd1b03f414170f
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Gonadal hormones play a vital role in driving motivated behavior. They not only modulate responses to naturally rewarding stimuli, but also influence responses to drugs of abuse. A commonality between gonadal hormones and drugs of abuse is that they
Externí odkaz:
https://doaj.org/article/1ca6c2254fd042928ffececc08ab8cee
Autor:
Kellie S Gross, Dieter D Brandner, Luis A Martinez, M Foster Olive, Robert L Meisel, Paul G Mermelstein
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162755 (2016)
The group I metabotropic glutamate receptors (mGluR1a and mGluR5) are important modulators of neuronal structure and function. Although these receptors share common signaling pathways, they are capable of having distinct effects on cellular plasticit
Externí odkaz:
https://doaj.org/article/a181654664a6407ab47e5dddd9223308
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18114 (2011)
The peptide corticotropin-releasing factor (CRF) was initially identified as a critical component of the stress response. CRF exerts its cellular effects by binding to one of two cognate G-protein coupled receptors (GPCRs), CRF receptor 1 (CRFR1) or
Externí odkaz:
https://doaj.org/article/5c0f4560e1cb4bf3a2d62d10aabe0874
Publikováno v:
Journal of neurochemistry. 97(2)
Persistent hyperalgesia is associated with increased expression of proteins that contribute to enhanced excitability of spinal neurons, however, little is known about how expression of these proteins is regulated. We tested the hypothesis that Substa
Publikováno v:
Genes, brain, and behavior. 4(1)
Sexual experience, like repeated drug use, produces long-term changes including sensitization in the nucleus accumbens and dorsal striatum. To better understand the molecular mechanisms underlying the neuroadaptations following sexual experience, we