Zobrazeno 1 - 10
of 14
pro vyhledávání: '"P G, Bhide"'
Autor:
Deirdre M. McCarthy, Cynthia Vied, Mia X. Trupiano, Angeli J. Canekeratne, Yuan Wang, Christopher Schatschneider, Pradeep G. Bhide
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
IntroductionFragile X syndrome is an inherited X-linked disorder associated with intellectual disabilities that begin in childhood and last a lifetime. The symptoms overlap with autism spectrum disorder, and the syndrome predominantly affects males.
Externí odkaz:
https://doaj.org/article/7b97051777db475c8c9844880dfa15ed
Autor:
Sara K. Jones, Deirdre M. McCarthy, Gregg D. Stanwood, Christopher Schatschneider, Pradeep G. Bhide
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Environmental exposures produce heritable traits that can linger in the population for one or two generations. Millions of individuals consume substances such as artificial sweeteners daily that are declared safe by regulatory agencies witho
Externí odkaz:
https://doaj.org/article/f96bf26dbbdf44c084d952dbd644ac38
Autor:
Gloria S. Lee, Devon L. Graham, Brenda L. Noble, Taylor S. Trammell, Deirdre M. McCarthy, Lisa R. Anderson, Marcelo Rubinstein, Pradeep G. Bhide, Gregg D. Stanwood
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2022)
Developmental dysregulation of dopamine D2 receptors (D2Rs) alters neuronal migration, differentiation, and behavior and contributes to the psychopathology of neurological and psychiatric disorders. The current study is aimed at identifying how cell-
Externí odkaz:
https://doaj.org/article/b76ed20b99fa491480d515ae259aedec
Publikováno v:
Cells, Vol 9, Iss 4, p 1035 (2020)
Cigarette smoke is a known exacerbator of age-related pathologies, such as cardiovascular disease (CVD), atherosclerosis, and cellular aging (senescence). However, the role of nicotine and its major metabolite cotinine is yet to be elucidated. Consid
Externí odkaz:
https://doaj.org/article/bae05449f6754a3ca61d6533656afbaf
Autor:
Deirdre M McCarthy, Thomas J Morgan, Sarah E Lowe, Matthew J Williamson, Thomas J Spencer, Joseph Biederman, Pradeep G Bhide
Publikováno v:
PLoS Biology, Vol 16, Iss 10, p e2006497 (2018)
Use of tobacco products is injurious to health in men and women. However, tobacco use by pregnant women receives greater scrutiny because it can also compromise the health of future generations. More men smoke cigarettes than women. Yet the impact of
Externí odkaz:
https://doaj.org/article/19004d8483074f0b926cd9a550bef29d
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0198064 (2018)
BACKGROUND:Cigarette smoking by pregnant women is associated with a significant increase in the risk for cognitive disorders in their children. Preclinical models confirm this risk by showing that exposure of the developing brain to nicotine produces
Externí odkaz:
https://doaj.org/article/3ed21359736f4b03ae1e311bfd964f68
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139103 (2015)
Drugs of abuse modify behavior by altering gene expression in the brain. Gene expression can be regulated by changes in DNA methylation as well as by histone modifications, which alter chromatin structure, DNA compaction and DNA accessibility. In ord
Externí odkaz:
https://doaj.org/article/08d35b96707d4a6c82c89427416a53d7
Dopamine receptor and Gα(olf) expression in DYT1 dystonia mouse models during postnatal development.
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123104 (2015)
BACKGROUND:DYT1 dystonia is a heritable, early-onset generalized movement disorder caused by a GAG deletion (ΔGAG) in the DYT1 gene. Neuroimaging studies and studies using mouse models suggest that DYT1 dystonia is associated with dopamine imbalance
Externí odkaz:
https://doaj.org/article/1a01dc510c90484994bd0194f5141247
Publikováno v:
The Journal of comparative neurology. 420(2)
delta-catenin is a member of the Armadillo repeat family and component of the adherens junction discovered in a two-hybrid assay as a bona fide interactor with presenilin-1 (Zhou et al., [1997], NeuroReport 8:2085-2090), a protein which carries mutat
Autor:
P G, Bhide, D O, Frost
Publikováno v:
The Journal of comparative neurology. 411(1)
Permanent, novel retinal projections to the principal thalamic somatosensory (ventrobasal) or auditory (medial geniculate) nuclei can be produced in adult hamsters if the superior colliculus is ablated bilaterally and the somatosensory and auditory l