Zobrazeno 1 - 5
of 5
pro vyhledávání: '"P F van Kuijk"'
Autor:
Melissa Vos, Ruben Boers, Anne L M Vriends, Joachim Boers, Patricia F van Kuijk, Winan J van Houdt, Geert J L H van Leenders, Michal Wagrodzki, Wilfred F J van IJcken, Joost Gribnau, Dirk J Grünhagen, Cornelis Verhoef, Stefan Sleijfer, Erik A C Wiemer
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228014 (2020)
Approximately one-third of the patients with well-differentiated liposarcoma (WDLPS) will develop a local recurrence. Not much is known about the molecular relationship between the primary tumor and the recurrent tumor, which is important to reveal p
Externí odkaz:
https://doaj.org/article/ed7c1158aab044249ae0a4a5efa1bab2
Autor:
Azadeh Amirnasr, Rob M Verdijk, Patricia F van Kuijk, Walter Taal, Stefan Sleijfer, Erik A C Wiemer
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183155 (2017)
Malignant peripheral nerve sheath tumors (MPNST) are rare, highly aggressive sarcomas that can occur spontaneously or from pre-existing plexiform neurofibromas in neurofibromatosis type1 (NF1) patients. MPNSTs have high local recurrence rates, metast
Externí odkaz:
https://doaj.org/article/e7b5eefcebaa46bd97199cd724d664d3
Autor:
Azadeh Amirnasr, Caroline M.M. Gits, Patricia F. van Kuijk, Marcel Smid, Anne L.M. Vriends, Piotr Rutkowski, Raf Sciot, Patrick Schöffski, Maria Debiec-Rychter, Stefan Sleijfer, Erik A. C. Wiemer
Publikováno v:
Cancers, Vol 11, Iss 6, p 882 (2019)
Despite the success of imatinib in advanced gastrointestinal stromal tumor (GIST) patients, 50% of the patients experience resistance within two years of treatment underscoring the need to get better insight into the mechanisms conferring imatinib re
Externí odkaz:
https://doaj.org/article/b2780d72ee3441ab9a1863fcfeb36bd7
Autor:
Antonius W. M. Boersma, Erik A.C. Wiemer, M T M van Jaarsveld, P F van Kuijk, Els M.J.J. Berns, Jaap Verweij, W F J van IJcken, Ignace Vergote, Ron H.J. Mathijssen, Evelyn Despierre, Joris Pothof, Jozien Helleman
Publikováno v:
Oncogene, 32(36), 4284-4293. Nature Publishing Group
Epithelial ovarian cancer is the most lethal gynecological malignancy in the Western world. A major impediment for the successful treatment is the development of drug resistance. The molecular processes that contribute to resistance have been extensi
Autor:
Erik A.C. Wiemer, Patrick Schöffski, Antonius W. M. Boersma, Stefan Sleijfer, Caroline M.M. Gits, Ron H.J. Mathijssen, Moniek B E Jonkers, W F J van IJcken, Agnieszka Wozniak, Piotr Rutkowski, P F van Kuijk, Raf Sciot, Jaap Verweij, Takahiro Taguchi, Maria Debiec-Rychter
Publikováno v:
British Journal of Cancer, 109(6), 1625-1635. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer
BACKGROUND: Gastrointestinal stromal tumours (GIST) are characterised by high expression of KIT and ETV1, which cooperate in GIST oncogenesis. Our aim was to identify microRNAs that are deregulated in GIST, have a role in GIST pathogenesis, and could