Zobrazeno 1 - 10
of 91
pro vyhledávání: '"P F Engstrom"'
Autor:
E B Goosenberg, James M. Gallo, P F Engstrom, Thomas C. Hamilton, Christine E. Szarka, T Halbherr, A M Balshem, G R Pfeiffer, F Green, Kang Shen Yao, M L Clapper, Peter J. O'Dwyer, H Frucht, Samuel Litwin, James M. Brennan
Publikováno v:
Journal of Clinical Investigation. 98:1210-1217
Prolonged exposure to mutagenic substances is strongly associated with an individual's risk of developing colorectal cancer. Clinical investigation of oltipraz as a chemopreventive agent is supported by its induction of the expression of detoxication
Autor:
C E, Szarka, K S, Yao, G R, Pfeiffer, A M, Balshem, S, Litwin, H, Frucht, E B, Goosenberg, P F, Engstrom, M L, Clapper, P J, O'Dwyer
Publikováno v:
Cancer detection and prevention. 25(4)
The dithiolethione oltipraz is being developed as a chemopreventive agent for many malignancies, including colorectal cancer, on the basis of its in vivo protective activity against chemically induced tumors in a variety of animal models. This protec
Publikováno v:
Journal of behavioral medicine. 24(3)
The purpose of the present study was to systematically compare the psychological and screening profiles of first-degree relatives (FDRs) of prostate cancer patients versus non-FDRs. FDRs (n = 56) and non-FDRs (n = 100), recruited through prostate can
Autor:
S C, Liu, Y, Hu, E R, Sauter, M L, Clapper, S Y, Chen, H E, Lanfranchi, P F, Engstrom, A J, Klein-Szanto
Publikováno v:
Analytical and quantitative cytology and histology. 21(2)
The expression of p53 and cyclin D1 proteins was analyzed by image analysis in oral premalignant lesions and normal oral mucosa.Punch biopsies from the normal oral mucosa were obtained from 20 normal donors and 41 patients with oral dysplastic leukop
Autor:
C A, Garay, P F, Engstrom
Publikováno v:
Oncology (Williston Park, N.Y.). 13(1)
Colorectal cancer is a major cause of death in the United States, where it accounts for approximately 57,000 deaths per year. Thus, the prevention of this disease would have a significant impact on public health. Chemoprevention is defined as the use
Autor:
S C, Liu, E R, Sauter, M L, Clapper, R S, Feldman, L, Levin, S Y, Chen, T J, Yen, E, Ross, P F, Engstrom, A J, Klein-Szanto
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 7(7)
The expression of several markers of epithelial cell proliferation was analyzed to establish baseline data for future chemoprevention studies of oral premalignant lesions. Punch biopsies (n = 60) from three different sites of oral mucosa (bucca, late
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 7(4)
Prostate-specific antigen (PSA) is produced by the female breast. Prior in vitro evidence suggests that PSA expression in breast epithelial cells is regulated by androgens and progestins but not estrogens. The purpose of this study was to determine w
Autor:
M L, Clapper, C E, Szarka, G R, Pfeiffer, T A, Graham, A M, Balshem, S, Litwin, E B, Goosenberg, H, Frucht, P F, Engstrom
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(1)
Previous studies suggest that cruciferous vegetables may provide protection against carcinogen exposure by inducing detoxification enzymes. ICR(Ha) mice were gavaged with broccoli tablets (1 g/kg), and colon tissues were collected after treatment. Gl
Autor:
E R, Sauter, M, Daly, K, Linahan, H, Ehya, P F, Engstrom, G, Bonney, E A, Ross, H, Yu, E, Diamandis
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 5(12)
Despite the fact that breast cancer is the most common non-cutaneous cancer and a leading cause of cancer deaths in women, accepted markers of breast cancer risk miss up to 40% of these tumors. Moreover, screening methods involving the analysis of ti
Autor:
P F, Engstrom, A B, Benson, A, Cohen, J, Doroshow, K, Kiel, J, Niederhuber, M, Roh, M, Tempero
Publikováno v:
Oncology (Williston Park, N.Y.). 10
In summary, the committee believes that a multidisciplinary approach is necessary for the management of the patient with colorectal cancer. The committee endorses the concept that treatment of patients on a clinical trial has priority over standard o