Zobrazeno 1 - 10
of 55
pro vyhledávání: '"P F, Kador"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Blast wave exposure, a leading cause of hearing loss and balance dysfunction among military personnel, arises primarily from direct mechanical damage to the mechanosensory hair cells and supporting structures or indirectly through excessive
Externí odkaz:
https://doaj.org/article/f0a96ac11a5b446b9e2ad72ee9d33d32
Autor:
Peter F Kador, Peng Zhang, Jun Makita, Zifeng Zhang, Changmei Guo, James Randazzo, Hiroyoshi Kawada, Neena Haider, Karen Blessing
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e49422 (2012)
Mouse models possessing green fluorescent protein (GFP) and/or human aldose reductase (hAR) in vascular tissues have been established and crossed with naturally diabetic Akita mice to produce new diabetic mouse models.Colonies of transgenic C57BL mic
Externí odkaz:
https://doaj.org/article/f78f137389ec4472a66891a5e4d1d28d
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18980 (2011)
Age-related cataract is a worldwide health care problem whose progression has been linked to oxidative stress and the accumulation of redox-active metals. Since there is no specific animal model for human age-related cataract, multiple animal models
Externí odkaz:
https://doaj.org/article/9de3e4b1bea74a54badd267474f0c238
Autor:
Zi-Feng Zhang, Jian Zhang, Yan-Nian Hui, Min-Hua Zheng, Xin-Ping Liu, Peter F Kador, Yu-Sheng Wang, Li-Bo Yao, Jian Zhou
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26102 (2011)
BACKGROUND: Human N-Myc downstream regulated gene2 (NDRG2), a novel gene has been cloned and shown to be related to a number of cellular processes, including proliferation, differentiation, stress, and apoptosis. NDRG2 has also been linked to age-rel
Externí odkaz:
https://doaj.org/article/47e03e802aa94efba2a0a40492702adc
Publikováno v:
Acta Ophthalmologica. 87
Diabetic dogs rapidly form bilateral sugar cataracts within one year of diagnosis. Similar sugar cataracts also form in galactose-fed dogs. Since topical KinostatTM has been shown to reverse initial cataract formation in young galactose-fed dogs, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36c181398c1d975519e59f7f2fec062c
https://doi.org/10.1111/j.1755-3768.2009.3142.x
https://doi.org/10.1111/j.1755-3768.2009.3142.x
Publikováno v:
Acta Ophthalmologica. 87
Age-related cataract and neurodegeneration has been linked to oxidative stress and increased lenticular levels of Fe and Cu, which can contribute to ROS generated through the Fenton Reaction. Since both antioxidants and chelating agents have both bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6492461c422ddb285319b11ba1eefb44
https://doi.org/10.1111/j.1755-3768.2009.3445.x
https://doi.org/10.1111/j.1755-3768.2009.3445.x
Publikováno v:
Acta Neuropathologica. 81:529-539
Aldose reductase was visualized by light and electron microscopy using a goat anti-rat antibody with immunoperoxidase and immunogold, respectively. Ouabain-sensitive, K(+)-dependent, p-nitro-phenylphosphatase, a component of (Na+, K+)-ATPase, was loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef068bd558d7e17e2985293987ba7e83
https://doi.org/10.1007/bf00310134
https://doi.org/10.1007/bf00310134
Publikováno v:
Eye (London, England). 22(10)
Asteroid hyalosis (AH) is a common degenerative process in which fatty calcium globules collect within the vitreous humour. The condition rarely causes visual disturbances, and surgical removal is only rarely required. The presence of AH has been ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8bc306f1ab363050d268e39b89be767
https://pubmed.ncbi.nlm.nih.gov/18344964
https://pubmed.ncbi.nlm.nih.gov/18344964
Publikováno v:
Journal of diabetes and its complications. 13(3)
Dogs fed a diet containing 30% galactose develop diabetes-like retinal capillary changes. As retinal capillary occlusion is commonly observed in diabetic retinopathy, neutrophil apoptosis and the interaction of neutrophils with retinal capillary endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2261f0feda719dadc96f20ad1171e64c
https://pubmed.ncbi.nlm.nih.gov/10509875
https://pubmed.ncbi.nlm.nih.gov/10509875
Publikováno v:
Advances in experimental medicine and biology. 463
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd9ad6bfb7b7de5d19f334838327e106
https://pubmed.ncbi.nlm.nih.gov/10352722
https://pubmed.ncbi.nlm.nih.gov/10352722