A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans

Autor: Marta R. Moksnes, Ailin F. Hansen, Brooke N. Wolford, Laurent F. Thomas, Humaira Rasheed, Anica Simić, Laxmi Bhatta, Anne Lise Brantsæter, Ida Surakka, Wei Zhou, Per Magnus, Pål R. Njølstad, Ole A. Andreassen, Tore Syversen, Jie Zheng, Lars G. Fritsche, David M. Evans, Nicole M. Warrington, Therese H. Nøst, Bjørn Olav Åsvold, Trond Peder Flaten, Cristen J. Willer, Kristian Hveem, Ben M. Brumpton

Publikováno v: Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)

Abstract Trace elements are important for human health but may exert toxic or adverse effects. Mechanisms of uptake, distribution, metabolism, and excretion are partly under genetic control but have not yet been extensively mapped. Here we report a c

Externí odkaz: https://doaj.org/article/a7e170131ef54ac2b581216700d4d812

Danish consumers’ knowledge about and willingness to buy dairy products close to the best‐before‐date

Autor: Carina V. Melgaard, Emily Voss, Majken F. Hansen, Marlene Lassen, Michelle Hvidtfeldt, Sujita Pandey, Morten Arendt Rasmussen, Marianne Thomsen

Publikováno v: Food Frontiers, Vol 5, Iss 2, Pp 494-507 (2024)

Abstract More than 700,000 tons of food are wasted annually in Denmark where dairy products are among the 10 most wasted food products. Therefore, this study aims to analyze Danish consumers’ understanding of the best‐before‐date label and rela

Externí odkaz: https://doaj.org/article/986345b4737345c3a6d1c798ae0fa626

Robust optimization of the Gross Tumor Volume compared to conventional Planning Target Volume-based planning in photon Stereotactic Body Radiation Therapy of lung tumors

Autor: Thomas L. Fink, Charlotte Kristiansen, Torben S. Hansen, Torben F. Hansen, Rune S. Thing

Publikováno v: Acta Oncologica, Vol 63, Iss 1 (2024)

Background: Robust optimization has been suggested as an approach to reduce the irradiated volume in lung Stereotactic Body Radiation Therapy (SBRT). We performed a retrospective planning study to investigate the potential benefits over Planning Targ

Externí odkaz: https://doaj.org/article/29c361c4d870455cb5d4689cd4283f9d

Genetic causal relationship between immune diseases and migraine: a Mendelian randomization study

Autor: Guanglu Li, Shaojie Duan, International Headache Genetics Consortium (IHGC), Tao Zheng, Tiantian Zhu, Baoquan Qu, Lei Liu, Zunjing Liu, Verneri Anttila, Ville Artto, Andrea C Belin, Anna Bjornsdottir, Gyda Bjornsdottir, Dorret I Boomsma, Sigrid Børte, Mona A Chalmer, Daniel I Chasman, Bru Cormand, Ester Cuenca-Leon, George Davey-Smith, Irene de Boer, Martin Dichgans, Tonu Esko, Tobias Freilinger, Padhraig Gormley, Lyn R Griffiths, Eija Hämäläinen, Thomas F Hansen, Aster VE Harder, Heidi Hautakangas, Marjo Hiekkala, Maria G Hrafnsdottir, M. Arfan Ikram, Marjo-Riitta Järvelin, Risto Kajanne, Mikko Kallela, Jaakko Kaprio, Mari Kaunisto, Lisette JA Kogelman, Espen S Kristoffersen, Christian Kubisch, Mitja Kurki, Tobias Kurth, Lenore Launer, Terho Lehtimäki, Davor Lessel, Lannie Ligthart, Sigurdur H Magnusson, Rainer Malik, Bertram Müller-Myhsok, Carrie Northover, Dale R Nyholt, Jes Olesen, Aarno Palotie, Priit Palta, Linda M Pedersen, Nancy Pedersen, Matti Pirinen, Danielle Posthuma, Patricia Pozo-Rosich, Alice Pressman, Olli Raitakari, Caroline Ran, Gudrun R Sigurdardottir, Hreinn Stefansson, Kari Stefansson, Olafur A Sveinsson, Gisela M Terwindt, Thorgeir E Thorgeirsson, Arn MJM vanden Maagdenberg, Cornelia van Duijn, Maija Wessman, Bendik S Winsvold, John-Anker Zwart.

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

BackgroundMigraine has an increased prevalence in several immune disorders, but genetic cause-effect relationships remain unclear. Mendelian randomization (MR) was used in this study to explore whether immune diseases are causally associated with mig

Externí odkaz: https://doaj.org/article/a30f6c7b567e43149a0c5afd66373445

Delayed Gut Colonization Changes Future Insulin Resistance and Hepatic Gene Expression but Not Adiposity in Obese Mice

Autor: Maria B. B. Ebert, Caroline M. J. Mentzel, Anders Brunse, Lukasz Krych, Camilla H. F. Hansen

Publikováno v: Journal of Obesity, Vol 2024 (2024)

Objective. The importance of early microbial dysbiosis in later development of obesity and metabolic disorders has been a subject of debate. Here we tested cause and effect in mice. Methods. Germ-free male Swiss Webster mice were colonized in a speci

Externí odkaz: https://doaj.org/article/811f6b4d287d4069b12ad660e4bdeccd