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Akademický článek

Truques de linguagem: implicatura e racionalidade em Paul Grice = Tricks of language: implication and rationality in Paul Grice = Trucos de lenguaje: implicatura y racionalidad en Paul Grice

Autor: Efken, Karl-Heinz

Publikováno v: Veritas, Vol 67, Iss 1, p ID38295 (2022)

A teoria da implicatura constitui o principal legado de Paul Grice aos modernos estudos da pragmática linguística. Embora associado à filosofia da linguagem ordinária, seu pensamento não se apresenta marcado pela aversão à sistematização te�

Externí odkaz: https://doaj.org/article/2389ad221b864e269df69da638fa7998

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Akademický článek

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Akademický článek

A Dimensão de Domínio na Constituição do Ego

Autor: Pedro Henrique de Oliveira Efken

Publikováno v: Revista Subjetividades, Vol 17, Iss 1, Pp 22-34 (2017)

O objetivo desse artigo é analisar a presença da dimensão de domínio na constituição do ego no pensamento freudiano. A noção freudiana de um aparelho psíquico forjado para dominar as excitações – que se originam no organismo e chegam à

Externí odkaz: https://doaj.org/article/cc1aafc18c3149dc8438ae6fdbc08d09

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P414 Comparative real-world effectiveness and persistence of vedolizumab versus anti-TNF therapy in biologic-naïve patients with Crohn′s disease with propensity score adjustment: two-year maintenance phase results from the prospective VEDO-IBD study

Autor: B Bokemeyer, S Plachta-Danielzik, P Efken, W Mohl, M Hoffstadt, T Krause, A Schweitzer, E Schnoy, R Atreya, N Teich, L Trentmann, R Ehehalt, S Franzenburg, P Hartmann, R di Giuseppe, S Schreiber

Publikováno v: Journal of Crohn's and Colitis. 17:i543-i544

Background To gain insight into vedolizumab (VEDO) use as a first-line biologic in Crohn′s disease (CD), this comparative, two-arm prospective real-world-evidence (RWE) study with propensity score (PS) adjustment aimed to assess, within the mainten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60bc42ec04155e0bfecf0e4601aaf691
https://doi.org/10.1093/ecco-jcc/jjac190.0544

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P742 Real-world evidence comparison on the effectiveness of ustekinumab vs anti-TNF or vedolizumab in ulcerative colitis: induction phase results from the prospective, observational RUN-UC study

Autor: B Bokemeyer, S Plachta-Danielzek, S Howaldt, W Mohl, P Efken, R Ehehalt, M Kahl, T Krause, L Trentmann, A Lügering, E Schnoy, C Jochum, S Fajardo Salmon, P Hartmann, E Gilman, S Schreiber

Publikováno v: Journal of Crohn's and Colitis. 17:i872-i873

Background Observational real-world evidence (RWE) studies on the effectiveness and safety of ustekinumab (UST) in ulcerative colitis (UC) are required in addition to RCTs, which are usually confined to selected patients and thus may not represent di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b89406dec8b42dc8297ec36d10282045
https://doi.org/10.1093/ecco-jcc/jjac190.0872

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P801 Maintenance phase effectiveness and persistence after two years in biologic-naïve ulcerative colitis patients treated with vedolizumab or anti-TNF (VEDO-IBD-study)

Autor: S Plachta-Danielzik, B Bokemeyer, P Efken, W Mohl, T Krause, M Hoffstadt, R Ehehalt, L Trentmann, A Schweitzer, P Jessen, S Franzenburg, P Hartmann, R di Giuseppe, S Schreiber

Publikováno v: Journal of Crohn's and Colitis. 17:i933-i934

Background In this two-arm prospective real-world-evidence (RWE) study with propensity score adjustment, we aimed to analyse the persistence of biologic therapy in biologic-naïve ulcerative colitis (UC) patients and to compare the 2-year effectivene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7bdb558bb20566aadf0d78e0dc281da
https://doi.org/10.1093/ecco-jcc/jjac190.0931

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P784 Real-world use and 6-month effectiveness of vedolizumab subcutaneous in IBD patients: results of the VEDO-IBD study

Autor: S Plachta-Danielzik, B Bokemeyer, P Efken, W Mohl, M Hoffstadt, T Krause, A Schweitzer, E Schnoy, R Ehehalt, L Trentmann, N Teich, R Atreya, S Franzenburg, P Hartmann, T Wenske, S Schreiber

Publikováno v: Journal of Crohn's and Colitis. 17:i918-i919

Background Since April 2020, vedolizumab (VEDO) has been available for use in IBD in intravenous (iv) and subcutaneous (sc) formulations. Due to limited data on real-world use and effectiveness, the objectives of this real-world evidence (RWE), obser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15dd84544f316d5caebd44a8fd1c6a95
https://doi.org/10.1093/ecco-jcc/jjac190.0914

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Akademický článek

Os Fundamentos do Conhecimento na Modernidade: o Método Científico em Popper

Autor: Alexcina Oliveira Cirne Vieira da Cunha, Karl Heinz Efken

Publikováno v: Revista Opinião Filosófica, Vol 5, Iss 2 (2017)

O presente artigo tem como objetivo apresentar os postulados teóricos, em especial o conceito de falseacionismo, do racionalismo crítico de Popper. Inicia com suas críticas ao positivismo lógico, bem como a sua recusa de fornecer cientificidade a

Externí odkaz: https://doaj.org/article/c8f193383c584557bb01e7ec6fb8ae95

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