Zobrazeno 1 - 10
of 11
pro vyhledávání: '"P E Soden"'
Autor:
J. Steven Leeder, Andrea Gaedigk, Krista J. Wright, Vincent S. Staggs, Sarah E. Soden, Yvonne S. Lin, Robin E. Pearce
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 10, Pp 2514-2527 (2022)
Abstract CYP2D6 substrates are among the most highly prescribed medications in teenagers and also commonly associated with serious adverse events. To investigate the relative contributions of genetic variation, growth, and development on CYP2D6 activ
Externí odkaz:
https://doaj.org/article/db29e85ec5c14e4484a7143f40dac3f8
Autor:
Marcella M Cline, Barbara Juarez, Avery Hunker, Ernesto G Regiarto, Bryan Hariadi, Marta E Soden, Larry S Zweifel
Publikováno v:
eLife, Vol 12 (2023)
The axonal guidance cue netrin-1 serves a critical role in neural circuit development by promoting growth cone motility, axonal branching, and synaptogenesis. Within the adult mouse brain, expression of the gene encoding (Ntn1) is highly enriched in
Externí odkaz:
https://doaj.org/article/22ed1545a810479381a09300cbd9607a
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Neuropeptides play an important role in modulating mesolimbic system function. However, while synaptic inputs to the ventral tegmental area (VTA) have been extensively mapped, the sources of many neuropeptides are not well resolved. Here, we mapped t
Externí odkaz:
https://doaj.org/article/aa4d23b01d6148d4bec9a628cfbd5fbf
Publikováno v:
Royal Society Open Science, Vol 8, Iss 11 (2021)
Improving the sustainability of synthesis is a major goal in green chemistry, which has been greatly aided by the development of asymmetric transition metal catalysis. Recent advances in asymmetric catalysis show that the ability to control the coord
Externí odkaz:
https://doaj.org/article/2b5790923bd7494981b9dfdc915d1510
Autor:
Avery C. Hunker, Marta E. Soden, Dasha Krayushkina, Gabriel Heymann, Rajeshwar Awatramani, Larry S. Zweifel
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4303-4316.e6 (2020)
Summary: Mice engineered for conditional, cell type-specific gene inactivation have dominated the field of mouse genetics because of the high efficiency of Cre-loxP-mediated recombination. Recent advances in CRISPR/Cas9 technologies have provided alt
Externí odkaz:
https://doaj.org/article/f916781c7e144b2eadb9e2cec1859172
Autor:
Michelle M. Giddens, Jennifer C. Wong, Jason P. Schroeder, Emily G. Farrow, Brilee M. Smith, Sharon Owino, Sarah E. Soden, Rebecca C. Meyer, Carol Saunders, J.B. LePichon, David Weinshenker, Andrew Escayg, Randy A. Hall
Publikováno v:
Neurobiology of Disease, Vol 106, Iss , Pp 181-190 (2017)
Progressive myoclonus epilepsies (PMEs) are disorders characterized by myoclonic and generalized seizures with progressive neurological deterioration. While several genetic causes for PMEs have been identified, the underlying causes remain unknown fo
Externí odkaz:
https://doaj.org/article/5eb7202d4a074122bb10f090415fcb3c
Autor:
Marta E. Soden, Samara M. Miller, Lauren M. Burgeno, Paul E.M. Phillips, Thomas S. Hnasko, Larry S. Zweifel
Publikováno v:
Cell Reports, Vol 16, Iss 2, Pp 304-313 (2016)
Nearly all animals engage in a complex assortment of social behaviors that are essential for the survival of the species. In mammals, these behaviors are regulated by sub-nuclei within the hypothalamus, but the specific cell types within these nuclei
Externí odkaz:
https://doaj.org/article/a36e2aedc86f4701ac317192e4d5afc8
Autor:
Graham L Jones, Marta E Soden, Cerise R Knakal, Heather Lee, Amanda S Chung, Elliott B Merriam, Larry S Zweifel
Publikováno v:
eLife, Vol 4 (2015)
The lateral amygdala (LA) acquires differential coding of predictive and non-predictive fear stimuli that is critical for proper fear memory assignment. The neurotransmitter dopamine is an important modulator of LA activity and facilitates fear memor
Externí odkaz:
https://doaj.org/article/687e900fc122481793a678a40cd1797d
Autor:
Andrew Makoff, Susan Chapman, Paul W. Sheppard, Claire L. Pollard, Amritpal Mudher, Abdur-Rasheed Asuni, L Raymond, Patrick A. Lewis, J Richardson, H T Rupniak, Todd E. Golde, Richard Killick, Brian H. Anderton, E Gower, Simon Lovestone, G M Gibb, T Iqbal, Matthew C. Murphy, Ian M. Varndell, P E Soden
Publikováno v:
Scopus-Elsevier
Alzheimer's disease (AD) is a disorder of two pathologies: amyloid plaques, the core of which is a peptide derived from the amyloid precursor protein (APP), and neurofibrillary tangles composed of highly phosphorylated tau. Protein kinase C (PKC) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26097ca1fd751feb26abfe3664db298
https://europepmc.org/articles/PMC6762860/
https://europepmc.org/articles/PMC6762860/
Autor:
Brian H. Anderton, T E O Schubert, P E Soden, Amritpal Mudher, Simon Lovestone, Jill C. Richardson, E Gower, H T R Rupniak, S C Chapman
Publikováno v:
Biochemical Society Transactions. 28:A36-A36