Zobrazeno 1 - 10
of 16
pro vyhledávání: '"P E J Van, Erp"'
Autor:
Sija Landman, Chiel van der Horst, Piet E. J. van Erp, Irma Joosten, Rob de Vries, Hans J. P. M. Koenen
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Inflammatory disorders like diabetes, systemic lupus erythematodes, inflammatory lung diseases, rheumatoid arthritis and multiple sclerosis, but also rejection of transplanted organs and GvHD, form a major burden of disease. Current classes
Externí odkaz:
https://doaj.org/article/935ebd4df33545c1bba2ae23cb1766b5
Autor:
Sija Landman, Marjan Cruijsen, Paulo C. M. Urbano, Gerwin Huls, Piet E. J. van Erp, Esther van Rijssen, Irma Joosten, Hans J. P. M. Koenen
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Regulatory T cells (Treg) can show plasticity whereby FOXP3 expression, the master transcription factor for Treg suppressor function, is lost and proinflammatory cytokines are produced. Optimal FOXP3 expression strongly depends on hypomethylation of
Externí odkaz:
https://doaj.org/article/984ed9a899d04d9281cc6f1b53ea3c87
Publikováno v:
Cosmetics, Vol 6, Iss 1, p 20 (2019)
The epidermal barrier function is disrupted in various inflammatory skin diseases. Accurate methods to measure skin barrier function are needed to assess the effect of therapeutic agents. Therefore, we developed a noninvasive multiparametric approach
Externí odkaz:
https://doaj.org/article/b40d307f52df435785ab2392489e1998
Autor:
M. M. van Rossum, J. M. Mommers, P. C. M. van de Kerkhof, G. J. de Jongh, C. A. E. M. van Hooijdonk, P. E. J. van Erp
Publikováno v:
Analytical Cellular Pathology, Vol 17, Iss 3, Pp 157-165 (1998)
Multi parameter flow cytometrical assays permit simultaneous assessment of proliferation, differentiation, and inflammation parameters. In this study, the validation of TO-PRO-3 iodide (TP3) compared to propidium iodide (PI) and DE-K10 compared to RK
Externí odkaz:
https://doaj.org/article/bb05782ecc1f4093a61fb9a8b1f4cdf0
Autor:
Vivian L de Oliveira, Romy R M C Keijsers, Peter C M van de Kerkhof, Marieke M B Seyger, Esther Fasse, Lars Svensson, Markus Latta, Hanne Norsgaard, Tord Labuda, Pieter Hupkens, Piet E J van Erp, Irma Joosten, Hans J P M Koenen
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45509 (2012)
Humanized mouse models offer a challenging possibility to study human cell function in vivo. In the huPBL-SCID-huSkin allograft model human skin is transplanted onto immunodeficient mice and allowed to heal. Thereafter allogeneic human peripheral blo
Externí odkaz:
https://doaj.org/article/ac14bfdebdd84d2491d0554f1db844c7
Publikováno v:
Skin pharmacology and physiology. 27(3)
Research has revealed new insights into the pathogenesis of psoriasis, leading to new therapeutic options. So far the order of changes in the pathogenesis of psoriasis is unclear. The responses to cutaneous leukotriene B4 (LTB4) application have been
Autor:
R R M C, Keijsers, H M J, van der Velden, P E J, van Erp, R T, de Boer-van Huizen, I, Joosten, H J P M, Koenen, P C M, van de Kerkhof
Publikováno v:
The British journal of dermatology. 168(6)
In the pathogenesis of psoriasis, proinflammatory T cells are strongly involved in the inflammatory process, where regulatory T-cell (Treg) function is impaired.As effective Treg function is associated with a numerical balance between Treg and effect
Publikováno v:
Journal of the European Academy of Dermatology and Venereology : JEADV. 27(8)
Basal cell carcinoma (BCC) is the most frequently occurring cancer in humans. Worldwide incidences rise about 10% each year, increasing the burden on dermatologists, general practitioners and pathologists as well as increasing costs for the health ca
Autor:
E A W, Wolberink, P E J, van Erp, R T, de Boer-van Huizen, P C M, van de Kerkhof, M J P, Gerritsen
Publikováno v:
The British journal of dermatology. 167(2)
In vivo reflectance confocal microscopy (RCM) is a novel, noninvasive imaging technique which enables imaging of skin at a cellular resolution comparable to conventional microscopy.We performed a pilot study to evaluate RCM as a noninvasive tool for
Publikováno v:
Journal of the European Academy of Dermatology and Venereology : JEADV. 26(2)
Protoporphyrin IX is present in psoriatic skin without the preceding application of aminolevulinic acid. Therefore, endogenous photosensitizers in psoriasis are a potential target for photodynamic treatment with high-dose visible light.In the present