Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.

Autor: Whitney Shatz, Philip E Hass, Nikhil Peer, Maciej T Paluch, Craig Blanchette, Guanghui Han, Wendy Sandoval, Ashley Morando, Kelly M Loyet, Vladimir Bantseev, Helen Booler, Susan Crowell, Amrita Kamath, Justin M Scheer, Robert F Kelley

Publikováno v: PLoS ONE, Vol 14, Iss 6, p e0218613 (2019)

Innovative protein engineering and chemical conjugation technologies have yielded an impressive number of drug candidates in clinical development including >80 antibody drug conjugates, >60 bispecific antibodies, >35 Fc-fusion proteins and >10 immuno

Externí odkaz: https://doaj.org/article/82a56a7b258c43e885de3b136fc2e95b

Correction: Corrigendum: The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation

Autor: Nadia Martinez-Martin, Sree R. Ramani, Jason A. Hackney, Irene Tom, Bernd J. Wranik, Michelle Chan, Johnny Wu, Maciej T. Paluch, Kentaro Takeda, Philip E. Hass, Hilary Clark, Lino C. Gonzalez

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-3 (2017)

Nature Communications 7: Article number: 11473 (2016); Published: 5 May 2016; Updated: 21 August 2017 In Supplementary Fig. 3 of this Article, the sequence given for CR1B_HAdV-D19a in the alignment shown is incorrect, and should have been identical t

Externí odkaz: https://doaj.org/article/2d3d3dc9d58a457a8a3707bac95a3833

Simultaneous operation of two soft x-ray free-electron lasers driven by one linear accelerator

Autor: B Faatz, E Plönjes, S Ackermann, A Agababyan, V Asgekar, V Ayvazyan, S Baark, N Baboi, V Balandin, N von Bargen, Y Bican, O Bilani, J Bödewadt, M Böhnert, R Böspflug, S Bonfigt, H Bolz, F Borges, O Borkenhagen, M Brachmanski, M Braune, A Brinkmann, O Brovko, T Bruns, P Castro, J Chen, M K Czwalinna, H Damker, W Decking, M Degenhardt, A Delfs, T Delfs, H Deng, M Dressel, H-T Duhme, S Düsterer, H Eckoldt, A Eislage, M Felber, J Feldhaus, P Gessler, M Gibau, N Golubeva, T Golz, J Gonschior, A Grebentsov, M Grecki, C Grün, S Grunewald, K Hacker, L Hänisch, A Hage, T Hans, E Hass, A Hauberg, O Hensler, M Hesse, K Heuck, A Hidvegi, M Holz, K Honkavaara, H Höppner, A Ignatenko, J Jäger, U Jastrow, R Kammering, S Karstensen, A Kaukher, H Kay, B Keil, K Klose, V Kocharyan, M Köpke, M Körfer, W Kook, B Krause, O Krebs, S Kreis, F Krivan, J Kuhlmann, M Kuhlmann, G Kube, T Laarmann, C Lechner, S Lederer, A Leuschner, D Liebertz, J Liebing, A Liedtke, L Lilje, T Limberg, D Lipka, B Liu, B Lorbeer, K Ludwig, H Mahn, G Marinkovic, C Martens, F Marutzky, M Maslocv, D Meissner, N Mildner, V Miltchev, S Molnar, D Mross, F Müller, R Neumann, P Neumann, D Nölle, F Obier, M Pelzer, H-B Peters, K Petersen, A Petrosyan, G Petrosyan, L Petrosyan, V Petrosyan, A Petrov, S Pfeiffer, A Piotrowski, Z Pisarov, T Plath, P Pototzki, M J Prandolini, J Prenting, G Priebe, B Racky, T Ramm, K Rehlich, R Riedel, M Roggli, M Röhling, J Rönsch-Schulenburg, J Rossbach, V Rybnikov, J Schäfer, J Schaffran, H Schlarb, G Schlesselmann, M Schlösser, P Schmid, C Schmidt, F Schmidt-Föhre, M Schmitz, E Schneidmiller, A Schöps, M Scholz, S Schreiber, K Schütt, U Schütz, H Schulte-Schrepping, M Schulz, A Shabunov, P Smirnov, E Sombrowski, A Sorokin, B Sparr, J Spengler, M Staack, M Stadler, C Stechmann, B Steffen, N Stojanovic, V Sychev, E Syresin, T Tanikawa, F Tavella, N Tesch, K Tiedtke, M Tischer, R Treusch, S Tripathi, P Vagin, P Vetrov, S Vilcins, M Vogt, A de Zubiaurre Wagner, T Wamsat, H Weddig, G Weichert, H Weigelt, N Wentowski, C Wiebers, T Wilksen, A Willner, K Wittenburg, T Wohlenberg, J Wortmann, W Wurth, M Yurkov, I Zagorodnov, J Zemella

Publikováno v: New Journal of Physics, Vol 18, Iss 6, p 062002 (2016)

Extreme-ultraviolet to x-ray free-electron lasers (FELs) in operation for scientific applications are up to now single-user facilities. While most FELs generate around 100 photon pulses per second, FLASH at DESY can deliver almost two orders of magni

Externí odkaz: https://doaj.org/article/43fc872f5ebf4d7393d33e88f9a3bab1

A monoclonal-antibody-based enzyme-linked immunosorbent assay of lipoprotein(a)

Autor: P. E. Hass, D. L. Eaton, Wai Lee Wong, B. Fendly, A. Berloui

Publikováno v: Clinical Chemistry. 36:192-197

Lipoprotein(a) [Lp(a)] is a low-density lipoprotein (LDL)-like lipoprotein particle recently described as a risk factor for premature coronary heart disease, stroke, and atherosclerosis. Structurally, Lp(a) is similar to LDL in that it has comparable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ded7c10c2d0997ad18c1f7cbd6d9ad6b
https://doi.org/10.1093/clinchem/36.2.192

Transferrin receptor in human placental brush border membranes. Studies on the binding of transferrin to placental membrane vesicles and the identification of a placental brush border glycoprotein with high affinity for transferrin

Autor: P E Hass, H H Sussman, H G Wada

Publikováno v: Journal of Biological Chemistry. 254:12629-12635

Evidence is presented demonstrating the existence of a receptor specific for transferrin on the brush border membrane of the human syncytial trophoblast. Equilibrium-binding studies were conducted using a placental vesicle preparation to demonstrate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bdd8213ffc8dc8bd99278b801e17b26
https://doi.org/10.1016/s0021-9258(19)86360-3