Zobrazeno 1 - 10
of 13
pro vyhledávání: '"P E, Simson"'
Publikováno v:
Alcoholism, clinical and experimental research. 25(11)
Behavioral studies using pharmacological manipulations that increase neuronal activity of the central nucleus of the amygdala (CeA) have implicated the CeA in enhancement of memory modulation. To date, however, there has been a dearth of studies inve
Publikováno v:
Behavioral neuroscience. 114(6)
The effect of beta-adrenergic receptor blockade on retention in a mildly aversive passive-avoidance procedure was investigated. Rats were given passive-avoidance training--1 trial per day for 4 days-and were administered saline, the centrally and per
Autor:
H E, Criswell, P E, Simson, D J, Knapp, L L, Devaud, T J, McCown, G E, Duncan, A L, Morrow, G R, Breese
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(1)
Previous investigations have suggested a relationship between zolpidem binding within specific brain regions and the ability of ethanol or zolpidem to enhance gamma-aminobutyric acid (GABA)-induced inhibition. The purpose of the present study was to
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(1)
The present investigation provides evidence that there is neuroanatomical specificity for ethanol enhancement of gamma-aminobutyric acid (GABA)-induced inhibition in mammalian brain and that the expression of a specific GABAA isoreceptor is associate
Publikováno v:
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. 2
The studies described will demonstrate that the subunit composition of a GABAA receptor allows ethanol to enhance responses to GABA. Since we have determined that ethanol will influence responses to glycine, nicotine and NMDA in some, but not all, ne
Autor:
P E, Simson, K B, Johnson, H A, Jurevics, H E, Criswell, T C, Napier, G E, Duncan, R A, Mueller, G R, Breese
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(3)
Lesioning of neonatal rats with the neurotoxin 6-hydroxydopamine (6-OHDA) reduced striatal dopamine (DA) levels to 3% of control levels and produced marked increases in the behavioral effects of the selective D1-DA receptor agonist SKF-38393 in these
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(2)
Administration of the selective D1-dopamine receptor agonist 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine (SKF-38393) to neonatal 6-hydroxydopamine-lesioned rats results in profound behavioral manifestations and induction of striatal c-
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 259(3)
The effect of ethanol on gamma-aminobutyric acid (GABA)-mediated inhibition of neurons of the inferior collicular cortex (IC) was investigated. Systemic administration of 0.5 g/kg ethanol, but not 0.25 g/kg ethanol, potentiated the inhibitory effect
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 258(1)
The ventral pallidum/substantia innominata (VP/SI) is an infracommissural extension of the dorsal globus pallidus (GP). Functional studies suggest that the VP/SI is indirectly influenced by dopamine (DA) via inputs from dopaminoceptive regions. Howev
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 257(1)
Recent studies have demonstrated that ethanol blocks N-methyl-D-aspartate (NMDA) responses in vitro. In the present study, evidence is provided that ethanol, when administered by the systemic route to rats, also inhibits NMDA-evoked electrophysiologi