Zobrazeno 1 - 10
of 11
pro vyhledávání: '"P E, Rakoczy"'
Autor:
P E, Rakoczy
Publikováno v:
Methods in molecular medicine. 47
Antisense DNA technology is a method to inhibit or downregulate the production of a target protein by using antisense DNA or RNA molecules. An antisense sequence is a DNA or RNA that is perfectly complementary to the target nucleotide sequence presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b3a015c71b299d1bc306d1572126002
https://pubmed.ncbi.nlm.nih.gov/21394580
https://pubmed.ncbi.nlm.nih.gov/21394580
Publikováno v:
Investigative ophthalmologyvisual science. 41(2)
To investigate the effects of recombinant adenovirus-mediated downregulation of cathepsin S (CatS) on the retinal pigment epithelium and/or neural retina in vivo.The expression of green fluorescent protein (gfp) after subretinal injection of a recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e06a006c3d0a99c243497c74a2e74008
https://pubmed.ncbi.nlm.nih.gov/10670491
https://pubmed.ncbi.nlm.nih.gov/10670491
Publikováno v:
Australian and New Zealand journal of ophthalmology. 27(3-4)
There is accumulating evidence that an increased expression of vascular endothelial growth factor from retinal pigment epithelial cells may be important in choroidal neovascularization. In vivo studies have demonstrated that subretinal injection of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0282319b35c3a4edbddc024e1b9003cc
https://pubmed.ncbi.nlm.nih.gov/10484206
https://pubmed.ncbi.nlm.nih.gov/10484206
Publikováno v:
Investigative ophthalmologyvisual science. 39(11)
To show the production of sense or antisense transcripts by recombinant adenoviruses, to investigate whether the transcripts produced were suitable for downregulating the expression of the targeted gene, cathepsin S (CatS), and to examine the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a500696c932426ad669da16097540ff
https://pubmed.ncbi.nlm.nih.gov/9761288
https://pubmed.ncbi.nlm.nih.gov/9761288
Publikováno v:
Current eye research. 17(6)
To investigate whether there is a difference in the expression of adenovirus transgenes in human retinal pigment epithelial cells when the vector was exposed to the apical or basal surface, the effect of transgene expression on rod outer segment (ROS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cc717c275ee8d40234502ef5258e1bb
https://pubmed.ncbi.nlm.nih.gov/9663858
https://pubmed.ncbi.nlm.nih.gov/9663858
Publikováno v:
Degenerative Retinal Diseases ISBN: 9781461377184
Age Related Macular Degeneration (AMD) is the leading cause of blindness in the developed world. With increasing life expectancy the prevalence of AMD (15-30%) in the age group of >75 years (Bressler1, Klein2, Vingerling3, Mitchell4) will significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442037c94650a4617e9a091123c2bd97
https://doi.org/10.1007/978-1-4615-5933-7_9
https://doi.org/10.1007/978-1-4615-5933-7_9
Publikováno v:
Current eye research. 15(9)
The primary aim of this study was to develop and characterize a simple flow cytometric method of quantifying rod outer segment (ROS) phagocytosis in cultured retinal pigment epithelial (RPE) cells. A secondary aim was to compare the kinetics of ROS p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9e7fff46f3f7ade8744d91a3d254c74
https://pubmed.ncbi.nlm.nih.gov/8921222
https://pubmed.ncbi.nlm.nih.gov/8921222
Publikováno v:
Australian and New Zealand journal of ophthalmology. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c485ef5cd8d0b78b004026f68ae0b47
https://pubmed.ncbi.nlm.nih.gov/8811255
https://pubmed.ncbi.nlm.nih.gov/8811255
Autor:
P E, Rakoczy, M C, Lai, S, Vijayasekaran, T, Robertson, L, Rapp, J, Papadimitriou, I, Constable
Publikováno v:
Current eye research. 15(1)
This paper describes the first successful in vivo application of antisense DNA technology to induce the accumulation of photoreceptor outer segment derived debris in the retina. An antisense oligonucleotide (CatSC), which was previously demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a07bb3aede57ff4b217cc96de8e8ae89
https://pubmed.ncbi.nlm.nih.gov/8631199
https://pubmed.ncbi.nlm.nih.gov/8631199
Publikováno v:
Investigative ophthalmologyvisual science. 35(12)
To investigate the presence and role of a recently cloned cysteine protease (cathepsin S) in the digestion of rod outer segments (ROS) by cultured retinal pigment epithelial (RPE) cells.RPE cell cultures were established from eye bank donor eyes. Tot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c69bb355a5ea2817823fcb82c254e5a
https://pubmed.ncbi.nlm.nih.gov/7960592
https://pubmed.ncbi.nlm.nih.gov/7960592