Zobrazeno 1 - 10
of 20
pro vyhledávání: '"P E, Purdue"'
Publikováno v:
Hydrology and Earth System Sciences, Vol 18, Iss 4, Pp 1369-1382 (2014)
When simulating social action in modeling efforts, as in socio-hydrology, an issue of obvious importance is how to ensure that social action by human agents is well-represented in the analysis and the model. Generally, human decision-making is either
Externí odkaz:
https://doaj.org/article/c5e7e5e0b4ef452ca4849b44a04839d9
Publikováno v:
Clinical Orthopaedics and Related Research. 454:251-261
The generation of prosthetic implant wear after total joint arthroplasty is recognized as the major initiating event in development of periprosthetic osteolysis and aseptic loosening, the leading complication of this otherwise successful surgical pro
Autor:
Zhenxin Shen, Kevin P. McHugh, P E Purdue, Merrilee R. Flannery, Regina P. O'Sullivan, Steven R. Goldring, Tania N. Crotti
Publikováno v:
Annals of the Rheumatic Diseases. 69:i83-i85
Analysis of tissues retrieved from the bone-pannus interface from patients with rheumatoid arthritis (RA) and studies in animal models of inflammatory arthritis provide strong evidence that osteoclasts, the cells that are essential for physiological
Publikováno v:
Neurochemical Research. 24:581-586
Rhizomelic chondrodysplasia punctata (RCDP) is a lethal autosomal recessive disease corresponding to complementation group 11 (CG11), the second most common of the thirteen CGs of peroxisomal biogenesis disorders (PBDs). RCDP is characterized by prox
Autor:
P E Purdue, Paul B. Lazarow
Publikováno v:
The Journal of Cell Biology
We have identified a novel peroxisomal targeting sequence (PTS) at the extreme COOH terminus of human catalase. The last four amino acids of this protein (-KANL) are necessary and sufficient to effect targeting to peroxisomes in both human fibroblast
Autor:
Paul B. Lazarow, P E Purdue
Publikováno v:
Journal of Biological Chemistry. 269:30065-30068
Publikováno v:
Human Genetics. 94:55-64
The autosomal recessive disease primary hyperoxaluria type 1 (PH1) is caused by a deficiency of the liver-specific peroxisomal enzyme alanine:glyoxylate amino-transferase (AGT). This paper concerns the identification, characterization and clinical us
Publikováno v:
Journal of Inherited Metabolic Disease. 17:487-499
Primary hyperoxaluria type 1 (PH1) is an autosomal recessive disease caused by a deficiency of the liver-specific peroxisomal enzyme alanine: glyoxylate aminotransferase (AGT). The disease is notable for its extensive heterogeneity at the clinical, b
Publikováno v:
The Plant Journal. 2:763-773
Two maize genes and cDNAs encoding the mitochondrial adenine nucleotide translocator (ANT), a nuclear-encoded inner mitochondrial membrane carrier protein, have previously been isolated in this laboratory. Sequence analysis revealed the existence of
Publikováno v:
Proceedings of the National Academy of Sciences. 88:10900-10904
In approximately one-third of primary hyperoxaluria type 1 patients, disease is associated with a unique protein sorting defect in which hepatic L-alanine:glyoxylate aminotransferase (AGT; EC 2.6.1.44), which is normally peroxisomal, is mistargeted t