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Akademický článek

Health professional and patient views of a novel prognostic test for melanoma: A theoretically informed qualitative study.

Autor: Jan Lecouturier, Helen Bosomworth, Marie Labus, Rob A Ellis, Penny E Lovat

Publikováno v: PLoS ONE, Vol 17, Iss 4, p e0265048 (2022)

ObjectivesCutaneous melanoma rates are steadily increasing. Up to 20% of patients diagnosed with AJCC Stage I/II melanomas will develop metastatic disease. To date there are no consistently reliable means to accurately identify truly high versus low-

Externí odkaz: https://doaj.org/article/b066aa54756a40b0a9efe11e4085744b

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Akademický článek

Proceedings of the International Cancer Imaging Society (ICIS) 16th Annual Teaching Course

Autor: Dow-Mu Koh, Sue Creviston Kaste, Sarah J. Vinnicombe, Giovanni Morana, Andrea Rossi, Christian J. Herold, Theresa C. McLoud, Kirk A. Frey, Bernhard Gebauer, Derek Roebuck, Jurgen J. Fütterer, Alexander J. Towbin, Thierry A. G. Huisman, Anne M. J. B. Smets, Jeong Min Lee, Hersh Chandarana, Marius E. Mayerhoefer, Markus Raderer, Alexander Haug, Matthias Eiber, Andrea Rockall, Aslam Sohaib, Victoria S Warbey, Hebert Alberto Vargas, Jay P. Heiken, Isaac R. Francis, Mahmoud M. Al-Hawary, Ravi K. Kaza, Mirko D’Onofrio, Harriet C. Thoeny, Ann D. King, Arnoldo Piccardo, Maria Luisa Garrè, Nick Reed, Carlos Rodriguez-Galindo, Ashish P. Wasnik, Stefan Diederich, Wim J. G. Oyen, Cheng Lee Chaw, Nicholas van As, Igor Vieira, Frederik De Keyzer, Elleke Dresen, Sileny Han, Ignace Vergote, Philippe Moerman, Frederic Amant, Michel Koole, Vincent Vandecaveye, R. Dresen, S. De Vuysere, F. De Keyzer, E. Van Cutsem, A. D’Hoore, A. Wolthuis, V. Vandecaveye, P. Pricolo, S. Alessi, P. Summers, E. Tagliabue, G. Petralia, C. Pfannenberg, B. Gückel, S. C. Schüle, A. C. Müller, S. Kaufmann, N. Schwenzer, M. Reimold, C. la Fougere, K. Nikolaou, P. Martus, G. J. Cook, G. K. Azad, B. P. Taylor, M. Siddique, J. John, J. Mansi, M. Harries, V. Goh, S. Seth, R. Burgul, A. Seth, S. Waugh, N. Muhammad Gowdh, C. Purdie, A. Evans, E. Crowe, A. Thompson, S. Vinnicombe, F. Arfeen, T. Campion, E. Goldstraw, M. D’Onofrio, V. Ciaravino, S. Crosara, R. De Robertis, R. Pozzi Mucelli, M. Uhrig, D. Simons, H. Schlemmer, Kate Downey, S. Murdoch, A. S. Al-adhami, S. Viswanathan, S. Smith, P. Jennings, D. Bowers, R. Soomal, T. M. Mutala, A. O. Odhiambo, N. Harish, M. Hall, M. Sproule, S. Sheridan, K. Y. Thein, C. H. Tan, Y. L. Thian, C. M. Ho, S. De Luca, C. Carrera, V. Blanchet, L. Alarcón, E. Eyheremnedy, B. K. Choudhury, K. Bujarbarua, G. Barman, E. Lovat, R. Ferner, V. S. Warbey, L. Potti, B. Kaye, A. Beattie, K. Dutton, A. A. Seth, F. Constantinidis, H. Dobson, R. Bradley, G. Bozas, G. Avery, A. Stephens, A. Maraveyas, S. Bhuva, C. A. Johnson, M. Subesinghe, N. Taylor, L. E. Quint, R. M. Reddy, G. P. Kalemkerian, G. González Zapico, E. Gainza Jauregui, R. Álvarez Francisco, S. Ibáñez Alonso, I. Tavera Bahillo, L. Múgica Álvarez, O. Francies, R. Wheeler, L. Childs, A. Adams, A. Sahdev, S. E. De Luca, M. E. Casalini Vañek, M. D. Pascuzzi, T. Gillanders, P. M. Ramos, E. P. Eyheremendy, C. Stove, M. Digby, M. Nazar, M. Wirtz, F. Troncoso, F. Saguier, D. J. Quint, L. Dang, M. Carlson, S. Leber, F. Silverstein, R. Rueben, B. Nazir, T. H. Teo, J. B. Khoo, K. Sharma, N. Gupta, B. Mathew, T. Jeyakumar, K. Harkins, S. Joshua, D. Christodoulou, S. Gourtsoyianni, A. Jacques, N. Griffin, J. Lee, J. A. Goodfellow, A. Yong, S. Jenkins, G. Joseph, K. Partington, A. Zanfardini, K. Cavanagh, E. Lau

Publikováno v: Cancer Imaging, Vol 16, Iss S1, Pp 1-34 (2016)

Table of contents O1 Tumour heterogeneity: what does it mean? Dow-Mu Koh O2 Skeletal sequelae in adult survivors of childhood cancer Sue Creviston Kaste O3 Locoregional effects of breast cancer treatment Sarah J Vinnicombe O4 Imaging of cancer therap

Externí odkaz: https://doaj.org/article/bbc9ed6b29934836b9bbcd92740a4db6

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Akademický článek

Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses

Autor: John D. Widdrington, Aurora Gomez-Duran, Angela Pyle, Marie-Helene Ruchaud-Sparagano, Jonathan Scott, Simon V. Baudouin, Anthony J. Rostron, Penny E. Lovat, Patrick F. Chinnery, A. John Simpson

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

In order to limit the adverse effects of excessive inflammation, anti-inflammatory responses are stimulated at an early stage of an infection, but during sepsis these can lead to deactivation of immune cells including monocytes. In addition, there is

Externí odkaz: https://doaj.org/article/e3d3a40efb8e4b5e9c5d241718315a08

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Apoptosis in neuroblastomas induced by interferon-gamma involves the CD95/CD95L pathway

Autor: M, Annicchiarico-Petruzzelli, F, Bernassola, P E, Lovat, C P, Redfern, A D, Pearson, G, Melino

Publikováno v: Medical and pediatric oncology. 36(1)

The CD95/CD95 ligand (CD95L) system is a key regulator of apoptosis. To evaluate a possible role of the CD95/CD95L system in human neuroblastoma (NB) cells, we investigated the constitutive and interferongamma (INFgamma)-induced expression of CD95 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fb5222f705c4830d1892594643e2b9b6
https://pubmed.ncbi.nlm.nih.gov/11464861

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Differential gene regulation by 9-cis and all-trans retinoic acid in neuroblastoma cells

Autor: P E, Lovat, M, Dobson, A J, Malcolm, A D, Pearson, C P, Redfern

Publikováno v: Medical and pediatric oncology. 36(1)

9-cis retinoic acid (RA) is more effective than all-trans RA at inducing neuroblastoma differentiation in vitro, and has distinct biological properties with respect to its ability to promote apoptosis in N-type neuroblastoma cells. The cellular effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::572ee677856ed96aa9525157adeb6e00
https://pubmed.ncbi.nlm.nih.gov/11464866

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Distinct properties of fenretinide and CD437 lead to synergistic responses with chemotherapeutic reagents

Autor: P E, Lovat, M, Ranalli, F, Bernassola, M, Tilby, A J, Malcolm, A D, Pearson, M, Piacentini, G, Melino, C P, Redfern

Publikováno v: Medical and pediatric oncology. 35(6)

The RARbeta/gamma-selective retinoids fenretinide and CD437 induce caspase-dependent apoptosis but generate free radicals independently of caspases. Apoptosis, but not free radical generation, induced by these retinoids is inhibited by RARbeta/gamma-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38634d8bfc174b65a6f710c6d30aab35
https://pubmed.ncbi.nlm.nih.gov/11107142

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Synergistic induction of apoptosis of neuroblastoma by fenretinide or CD437 in combination with chemotherapeutic drugs

Autor: P E, Lovat, M, Ranalli, F, Bernassola, M, Tilby, A J, Malcolm, A D, Pearson, M, Piacentini, G, Melino, C P, Redfern

Publikováno v: International journal of cancer. 88(6)

Retinoic acid therapy improves the survival of children with neuroblastoma and 13-cis retinoic acid now forms an important component of treatment for residual disease of stage IV neuroblastoma after chemotherapy. However, although 13-cis retinoic aci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a3578fde06f39ed2d59800409943c18
https://pubmed.ncbi.nlm.nih.gov/11093824

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9-cis retinoic acid--a better retinoid for the modulation of differentiation, proliferation and gene expression in human neuroblastoma

Autor: P E, Lovat, H, Irving, A J, Malcolm, A D, Pearson, C P, Redfern

Publikováno v: Journal of neuro-oncology. 31(1-2)

To date, the clinical success of 13-cis or all-trans retinoic acid in the treatment of neuroblastoma has been disappointing. In vivo, 13-cis will isomerise to both all-trans and 9-cis retinoic acid, believed to be the main biologically-active isomers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79508679d444a4e8336ac9bc11392e42
https://pubmed.ncbi.nlm.nih.gov/9049833

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