Zobrazeno 1 - 10
of 58
pro vyhledávání: '"P E, LIND"'
Autor:
Jason Deng, Svetlana Belyanskaya, Ninad Prabhu, Christopher Arico-Muendel, Hongfeng Deng, Christopher B. Phelps, David I. Israel, Hongfang Yang, Joseph Boyer, G. Joseph Franklin, Jeremy L. Yap, Kenneth E. Lind, Ching-Hsuan Tsai, Christine Donahue, Jennifer D. Summerfield
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100171- (2024)
DNA-encoded small molecule library technology has recently emerged as a new paradigm for identifying ligands against drug targets. To date, it has been used to identify ligands against targets that are soluble or overexpressed on cell surfaces. Here,
Externí odkaz:
https://doaj.org/article/200cb0758edc446ea0423cf022c88bf1
Autor:
Stine H. Kresse, Sara Brandt-Winge, Heidi Pharo, Bjørnar T. B. Flatin, Marine Jeanmougin, Hege Marie Vedeld, Guro E. Lind
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background DNA methylation biomarkers in circulating cell-free DNA (cfDNA) have great clinical potential for cancer management. Most methods for DNA methylation analysis require bisulfite conversion, causing DNA degradation and loss. This is
Externí odkaz:
https://doaj.org/article/3533e452970e4e5a9487c7ab1707a11a
Autor:
Heidi M. Namløs, Magne Skårn, Deeqa Ahmed, Iwona Grad, Kim Andresen, Stine H. Kresse, Else Munthe, Massimo Serra, Katia Scotlandi, Antonio Llombart-Bosch, Ola Myklebost, Guro E. Lind, Leonardo A. Meza-Zepeda
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Osteosarcoma is the most common primary malignant tumour of bone occurring in children and young adolescents and is characterised by complex genetic and epigenetic changes. The miRNA miR-486-5p has been shown to be downregulated i
Externí odkaz:
https://doaj.org/article/b508152fbe6b4d9db3a0cc3f2bf17690
Autor:
Joanna Szydzik, Dan E. Lind, Badrul Arefin, Yeshwant Kurhe, Ganesh Umapathy, Joachim Tetteh Siaw, Arne Claeys, Jonatan L. Gabre, Jimmy Van den Eynden, Bengt Hallberg, Ruth H. Palmer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Effective therapeutic options are still needed in neuroblastoma treatment. Here, the authors, through a comprehensive proteomics analysis, identify ATR as a potential therapeutic target of neuroblastoma and demonstrate the efficacy of the ATR inhibit
Externí odkaz:
https://doaj.org/article/06e9a92a8a164615981fa91b32e6d409
Autor:
Arman Romiani, Johan Spetz, Emman Shubbar, Dan E. Lind, Bengt Hallberg, Ruth H. Palmer, Eva Forssell-Aronsson
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background Neuroblastoma (NB) is one of the most frequently diagnosed tumors in infants. NB is a neuroendocrine tumor type with various characteristics and features, and with diverse outcome. The most malignant NBs have a 5-year survival rat
Externí odkaz:
https://doaj.org/article/f32ab4ad67f542fb86538f920f39e8ef
Autor:
Pei-Suen Tsou, Chenyang Lu, Mikel Gurrea-Rubio, Sei Muraoka, Phillip L. Campbell, Qi Wu, Ellen N. Model, Matthew E. Lind, Sirapa Vichaikul, Megan N. Mattichak, William D. Brodie, Jonatan L. Hervoso, Sarah Ory, Camila I. Amarista, Rida Pervez, Lucas Junginger, Mustafa Ali, Gal Hodish, Morgan M. O’Mara, Jeffrey H. Ruth, Aaron M. Robida, Andrew J. Alt, Chengxin Zhang, Andrew G. Urquhart, Jeffrey N. Lawton, Kevin C. Chung, Tristan Maerz, Thomas L. Saunders, Vincent E. Groppi, David A. Fox, M. Asif Amin
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
CD13, an ectoenzyme on myeloid and stromal cells, also circulates as a shed, soluble protein (sCD13) with powerful chemoattractant, angiogenic, and arthritogenic properties, which require engagement of a G protein–coupled receptor (GPCR). Here we i
Externí odkaz:
https://doaj.org/article/e5e9835fa1944ab4a428208a7bd7d3dd
Autor:
Joran Martijn, Max E. Schön, Anders E. Lind, Julian Vosseberg, Tom A. Williams, Anja Spang, Thijs J. G. Ettema
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
A study of the first genomes of the marine Hikarchaeia, the closest known relatives of Haloarchaea, is presented. Their inclusion in ancestral reconstructions unveils an intermediate stage in the evolutionary transition from ancestral anaerobic metha
Externí odkaz:
https://doaj.org/article/b489fb7a1f9d412bb22c7e7f72b441fb
Autor:
Kimberly E. Lind, Magdalena Z. Raban, Lindsey Brett, Mikaela L. Jorgensen, Andrew Georgiou, Johanna I. Westbrook
Publikováno v:
Population Health Metrics, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Background The number of older Australians using aged care services is increasing, yet there is an absence of reliable data on their health. Multimorbidity in this population has not been well described. A clear picture of the health status
Externí odkaz:
https://doaj.org/article/b31b71344389428295bf6a47a925a72f
Publikováno v:
BMC Health Services Research, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Internationally, point prevalence surveys are the main source of antibiotic use data in residential aged care (RAC). Our objective was to describe temporal trends in antibiotic use and antibiotics flagged for restricted use, resid
Externí odkaz:
https://doaj.org/article/03ee74610cbc40029f7421f5ddb6162f
Autor:
Marine Jeanmougin, Annette B. Håvik, Lina Cekaite, Petter Brandal, Anita Sveen, Torstein R. Meling, Trude H. Ågesen, David Scheie, Sverre Heim, Ragnhild A. Lothe, Guro E. Lind
Publikováno v:
Molecular Oncology, Vol 14, Iss 5, Pp 1016-1027 (2020)
Glioblastoma (GBM), the most aggressive form of brain cancer, is characterized by a high level of molecular heterogeneity, and infiltration by various immune and stromal cell populations. Important advances have been made in deciphering the microenvi
Externí odkaz:
https://doaj.org/article/50f176e97628490093af05af0a6840dd