Zobrazeno 1 - 10
of 40
pro vyhledávání: '"P E, Klotman"'
Autor:
Alessandra Gallinaro, Maria Franca Pirillo, Yoann Aldon, Serena Cecchetti, Zuleika Michelini, Antonella Tinari, Martina Borghi, Andrea Canitano, Paul F. McKay, Roberta Bona, Maria Fenicia Vescio, Felicia Grasso, Maria Blasi, Silvia Baroncelli, Gabriella Scarlatti, Celia LaBranche, David Montefiori, Mary E. Klotman, Rogier W. Sanders, Robin J. Shattock, Donatella Negri, Andrea Cara
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Integrase Defective Lentiviral Vectors (IDLVs) represent an attractive vaccine platform for delivering HIV-1 antigens, given their ability to induce specific and persistent immune responses in both mice and non-human primates (NHPs). Recent
Externí odkaz:
https://doaj.org/article/94f8ebf4de2b4e68add95d41c53acdd3
Autor:
Roberta Bona, Zuleika Michelini, Chiara Mazzei, Alessandra Gallinaro, Andrea Canitano, Martina Borghi, Maria Fenicia Vescio, Antonio Di Virgilio, Maria Franca Pirillo, Mary E. Klotman, Donatella Negri, Andrea Cara
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 263-275 (2021)
Integrase-defective lentiviral vectors (IDLVs) represent an attractive platform for vaccine development as a result of the ability to induce persistent humoral- and cellular-mediated immune responses against the encoded transgene. Compared with the p
Externí odkaz:
https://doaj.org/article/fb5aec3a55ec447ebb7f66eedf533028
Autor:
Andrew J. Zimolzak, Katherine Sippel, Jessica A. Davila, Michael E. DeBakey, Vamshi Punugoti, Paul E. Klotman, Laura A. Petersen, Gloria Liao, Lee Leiber, Christopher I. Amos
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 127-128 (2023)
OBJECTIVES/GOALS: In 2020, Baylor College of Medicine held a datathon to introduce a data warehouse, identify its capabilities/limitations, foster collaborations, and engage trainees. The event was held again in 2022, and lessons learned (e.g., tools
Externí odkaz:
https://doaj.org/article/5488f5496061402692500e84589af2b7
Autor:
Yi-Yu Lin, Ian Belle, Maria Blasi, Min-Nung Huang, Anne F. Buckley, Wes Rountree, Mary E. Klotman, Andrea Cara, Donatella Negri
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 532-544 (2020)
We previously developed integrase-defective lentiviral vectors (IDLVs) as an antigen delivery system for inducing strong and prolonged immunity in animal models. Here, we examined the association between persistence of antigen expression and durabili
Externí odkaz:
https://doaj.org/article/103e5f7dba2742d492fc44ae81fb0b05
Autor:
Andrew J. Zimolzak, Jessica A. Davila, Vamshi Punugoti, Ashok Balasubramanyam, Paul E. Klotman, Laura A. Petersen, Ryan H. Rochat, Gloria Liao, Rory R. Laubscher, Lee Leiber, Christopher I. Amos
Publikováno v:
Journal of Clinical and Translational Science, Vol 6 (2022)
In 2020, Baylor College of Medicine held a datathon to inform potential users of a new data warehouse, allow users to address clinical questions, identify warehouse capabilities and limitations, foster collaborations, and engage trainees. Senior facu
Externí odkaz:
https://doaj.org/article/2b7ba56ecdc845ca9458cda1b9ad400b
Autor:
Thomas Hays, Avi Ma'ayan, Neil R Clark, Christopher M Tan, Avelino Teixeira, Angela Teixeira, Jae W Choi, Nora Burdis, Sung Yun Jung, Amol O Bajaj, Bert W O'Malley, John C He, Deborah P Hyink, Paul E Klotman
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100660 (2014)
MYH9 encodes non-muscle myosin heavy chain IIA (NMMHCIIA), the predominant force-generating ATPase in non-muscle cells. Several lines of evidence implicate a role for MYH9 in podocytopathies. However, NMMHCIIA's function in podocytes remains unknown.
Externí odkaz:
https://doaj.org/article/d884dc3c91e144a4801a86ba899f17b5
Autor:
Alessandra Rossi, Zuleika Michelini, Pasqualina Leone, Martina Borghi, Maria Blasi, Roberta Bona, Massimo Spada, Felicia Grasso, Alessio Gugliotta, Mary E Klotman, Andrea Cara, Donatella Negri
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107377 (2014)
Many infectious agents infiltrate the host at the mucosal surfaces and then spread systemically. This implies that an ideal vaccine should induce protective immune responses both at systemic and mucosal sites to counteract invasive mucosal pathogens.
Externí odkaz:
https://doaj.org/article/b730c413fe28425ead76eee73811e97b
Autor:
Christina M Wyatt, George J Schwartz, Willis Owino Ong'or, Joseph Abuya, Alison G Abraham, Charles Mboku, Loice B M'mene, Winnie J Koima, Mathew Hotta, Paula Maier, Paul E Klotman, Kara Wools-Kaloustian
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69601 (2013)
More than two-thirds of the world's HIV-positive individuals live in sub-Saharan Africa, where genetic susceptibility to kidney disease is high and resources for kidney disease screening and antiretroviral therapy (ART) toxicity monitoring are limite
Externí odkaz:
https://doaj.org/article/cfaf4fcf061c4c79ad98d6c63efb0dc2
Autor:
P E Klotman
Publikováno v:
American Journal of Kidney Diseases. 31:719-722
Publikováno v:
The Journal of Immunology. 152:867-876
To investigate the role of leukotrienes in renal allograft rejection, we studied the effects of specific leukotriene inhibitors in a rat kidney transplant model. The enhanced renal production of leukotrienes observed in allograft recipients was reduc