Zobrazeno 1 - 10
of 17
pro vyhledávání: '"P E, Hurwitz"'
Autor:
Kathleen E. Hurwitz, Oluwaseyi O. Isehunwa, Kayla R. Hendrickson, Manjeetha Jaggernath, Yolandie Kriel, Patricia M. Smith, Mxolisi Mathenjwa, Kara Bennett, Christina Psaros, Jared M. Baeten, David R. Bangsberg, Jessica E. Haberer, Jennifer A. Smit, Lynn T. Matthews
Publikováno v:
Frontiers in Reproductive Health, Vol 5 (2023)
BackgroundDaily, oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) as pre-exposure prophylaxis (PrEP) reduces HIV acquisition for African women. Adherence is key to efficacy and patterns of adherence can be highly variable in real-world sett
Externí odkaz:
https://doaj.org/article/0195e8978921458f9e1c5c058ac2ac92
Autor:
Robert S. Seitz, Michael E. Hurwitz, Tyler J. Nielsen, Daniel B. Bailey, Matthew G. Varga, Brian Z. Ring, Carrie F. Metts, Brock L. Schweitzer, Kimberly McGregor, Douglas T. Ross
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background The IO Score is a 27-gene immuno-oncology (IO) classifier that has previously predicted benefit to immune checkpoint inhibitor (ICI) therapy in triple negative breast cancer (TNBC) and non-small cell lung cancer (NSCLC). It genera
Externí odkaz:
https://doaj.org/article/559b3f8416ed47f4ba8dbc1a517b7989
Autor:
Lynn T Matthews, Esther C Atukunda, Moran Owembabazi, Kato Paul Kalyebera, Christina Psaros, Pooja Chitneni, Craig W Hendrix, Mark A Marzinke, Peter L Anderson, Oluwaseyi O Isehunwa, Kathleen E Hurwitz, Kara Bennett, Winnie Muyindike, David R Bangsberg, Jessica E Haberer, Jeanne M Marrazzo, Mwebesa Bosco Bwana
Publikováno v:
PLoS Medicine, Vol 20, Iss 2, p e1004088 (2023)
BackgroundIn Uganda, fertility rates and adult HIV prevalence are high, and many women conceive with partners living with HIV. Pre-exposure prophylaxis (PrEP) reduces HIV acquisition for women and, therefore, infants. We developed the Healthy Familie
Externí odkaz:
https://doaj.org/article/46786adee7ed4d5780dd8be9948d9ad5
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
Concerns pertaining to health and to problems in close relationships are both known to be major stressors, yet existing tools are inadequate to assess individual reactions to such stressors. Thus, we sought to develop and preliminarily validate a str
Externí odkaz:
https://doaj.org/article/4312d30f1f7242b8a354925389730b74
Autor:
María Concepción Izquierdo, Niroshan Shanmugarajah, Samuel X. Lee, Michael J. Kraakman, Marit Westerterp, Takumi Kitamoto, Michael Harris, Joshua R. Cook, Galina A. Gusarova, Kendra Zhong, Elijah Marbuary, InSug O-Sullivan, Nikolaus Rasmus, Stefania Camastra, Terry G. Unterman, Ele Ferrannini, Barry E. Hurwitz, Rebecca A. Haeusler
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 7 (2022)
Multiple beneficial cardiovascular effects of HDL depend on sphingosine-1-phosphate (S1P). S1P associates with HDL by binding to apolipoprotein M (ApoM). Insulin resistance is a major driver of dyslipidemia and cardiovascular risk. However, the mecha
Externí odkaz:
https://doaj.org/article/1bec1268dd814e7492b3638624ca8bed
Bempegaldesleukin plus nivolumab in first-line renal cell carcinoma: results from the PIVOT-02 study
Autor:
Mario Sznol, Adi Diab, Jonathan Zalevsky, Ute Hoch, Mehmet A Bilen, Giovanni Grignani, Nizar M Tannir, Erika Puente, Arjun V Balar, Daniel C Cho, Arlene O Siefker-Radtke, Lily Tang, David Chien, Arkopal Choudhury, Danni Yu, Sue L Currie, Mary A Tagliaferri, Michael E Hurwitz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/b068e058e3794225a3c64c98a9d5c726
Autor:
Amr E. Abouleish, Sandhya R. Vinta, Sarah M. Shabot, Nikul V. Patel, Erin E. Hurwitz, Partha Krishnamurthy, Michelle Simon
Publikováno v:
Perioperative Medicine, Vol 9, Iss 1, Pp 1-12 (2020)
Abstract Background A successful anesthesia pre-assessment clinic needs to identify patients who need further testing, evaluation, and optimization prior to the day of surgery to avoid delays and cancelations. Although the ASA Physical Status Classif
Externí odkaz:
https://doaj.org/article/d31a825fbdcd43af8592ca65591c836d
Autor:
Meenu Sharma, Hiep Khong, Faisal Fa’ak, Salah-Eddine Bentebibel, Louise M. E. Janssen, Brent C. Chesson, Caitlin A. Creasy, Marie-Andrée Forget, Laura Maria S. Kahn, Barbara Pazdrak, Binisha Karki, Yared Hailemichael, Manisha Singh, Christina Vianden, Srinivas Vennam, Uddalak Bharadwaj, David J. Tweardy, Cara Haymaker, Chantale Bernatchez, Shixia Huang, Kimal Rajapakshe, Cristian Coarfa, Michael E. Hurwitz, Mario Sznol, Patrick Hwu, Ute Hoch, Murali Addepalli, Deborah H. Charych, Jonathan Zalevsky, Adi Diab, Willem W. Overwijk
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Interleukin-2 can induce an anti-tumour response, but is associated with toxicity. Here, the authors demonstrate that an engineered interleukin-2 promotes intratumoral T regulatory cell depletion while enhancing effective anti-tumour CD8+ T cell resp
Externí odkaz:
https://doaj.org/article/ef1801862b2840b0a440db03c657db66
Autor:
Claudia A. Martinez, Rishi Rikhi, Mollie S. Pester, Meela Parker, Alex Gonzalez, Michaela Larson, Jennifer Chavez, Armando Mendez, Jeffrey K. Raines, Michael A. Kolber, Ivonne H. Schulman, Maria L. Alcaide, Barry E. Hurwitz
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Objective Indices of cardiovascular disease (CVD) risk, vascular endothelial dilation, arterial stiffness and endothelial repair were examined in persons with HIV (PWH) on an antiretroviral therapy (ART) that included abacavir (ABC+) in comparison wi
Externí odkaz:
https://doaj.org/article/e5194188b65e4569955a729b3f36c420
Autor:
Katrina Swett, Carlos J Rodriguez, Neil Schneiderman, Martha L Daviglus, Barry E Hurwitz, Qibin Qi, Robert Kaplan, Kelly R Evenson, Andrew E Berdy, Bharathi Upadhya, Sonia Ponce, Richard B Stacey, Priscilla M Vasquez, Mayank Kansal
Publikováno v:
Open Heart, Vol 8, Iss 2 (2021)
Objective The cross-sectional association between accelerometer-measured physical activity (PA), sedentary behaviour (SB) and cardiac structure and function is less well described. This study’s primary aim was to compare echocardiographic measures
Externí odkaz:
https://doaj.org/article/ebdd9642b9b0407fabcfc6cd446fb26f