Zobrazeno 1 - 10
of 43
pro vyhledávání: '"P E, Crewther"'
Autor:
Leann Tilley, Robin F. Anders, P E Crewther, Andrew M. Coley, Naomi Vittoria. Campanale, Anthony N. Hodder, Joanne L. Casey, Michael Foley
Publikováno v:
Protein Engineering, Design and Selection. 14:691-698
We describe an approach for the rapid mapping of epitopes within a malaria antigen using a combination of phage display techniques. Phage display of antigen fragments identifies the location of the epitopes, then random peptide libraries displayed on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efee22195cb5f12d41ee61fdb6c8d87
https://doi.org/10.1093/protein/14.9.691
https://doi.org/10.1093/protein/14.9.691
Publikováno v:
Infection and Immunity. 69:3286-3294
Plasmodium falciparum infections in malaria-naive individuals can lead to severe morbidity, which may be life threatening if untreated. Continued exposure to infection leads to a degree of immunity, and consequently, older children and adults living
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c658f7ca9fd790fed964f53cb6caf9e
https://doi.org/10.1128/iai.69.5.3286-3294.2001
https://doi.org/10.1128/iai.69.5.3286-3294.2001
Publikováno v:
The Journal of Immunology. 165:389-396
Apical membrane Ag 1 (AMA1) is a leading malaria vaccine candidate. Homologues of AMA1 can induce protection in mice and monkeys, but the mechanism of immunity is not understood. Mice immunized with a refolded, recombinant, Plasmodium chabaudi AMA1 f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2006394ddd7a2bc053c4292b2a2fefd0
https://doi.org/10.4049/jimmunol.165.1.389
https://doi.org/10.4049/jimmunol.165.1.389
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 81, Pp 63-68 (1986)
Externí odkaz:
https://doaj.org/article/f2c74b35d6e54023b11572eed41b0a03
Autor:
S J Edwards, David Pye, Mary L.S.M. Matthew, Robin F. Anders, P E Crewther, Mai B. Margetts, Bronwyn Pollock
Publikováno v:
Vaccine. 16:240-247
The Plasmodium merozoite surface antigen apical membrane antigen-1 (AMA-1) has previously been shown to provide partial protection to Saimiri and rhesus monkeys immunised with recombinant Plasmodium fragile or parasite-derived Plasmodium knowlesi AMA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5390aae8bc58c8c9d8c1f8513459b8
https://doi.org/10.1016/s0264-410x(97)88331-4
https://doi.org/10.1016/s0264-410x(97)88331-4
Publikováno v:
The Journal of Immunology. 159:5535-5544
We have investigated the proliferative and Th cell responses to the Plasmodium chabaudi adami DS homologue of the Plasmodium falciparum apical membrane Ag 1 (AMA-1), a leading malaria vaccine candidate. Immunodominant T cell epitopes were defined fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c175e1081647bdfa8bcf23a5874e2acf
https://doi.org/10.4049/jimmunol.159.11.5535
https://doi.org/10.4049/jimmunol.159.11.5535
Autor:
Gavin E. Reid, Richard J. Simpson, Robin F. Anders, Mary L.S.M. Matthew, P E Crewther, Robert L. Moritz, Anthony N. Hodder
Publikováno v:
Journal of Biological Chemistry. 271:29446-29452
Apical membrane antigen-1 (AMA-1) of Plasmodium falciparum is one of the leading asexual blood stage antigens being considered for inclusion in a malaria vaccine. The ability of this molecule to induce a protective immune response has been shown to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d3273ccb4bf2c6121839a45fc5d46c
https://doi.org/10.1074/jbc.271.46.29446
https://doi.org/10.1074/jbc.271.46.29446
Publikováno v:
Neuroreport, Vol. 21, No 13 (2010) pp. 897-901
Complete deficiency of a member of the type II transmembrane serine protease family, tmprss1 (also known as hepsin), is associated with severe to profound hearing loss in mice and a gross enlargement of the tectorial membrane in the cochlea. Levels o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03088d56b8038f81a3fbc754e77f7deb
https://europepmc.org/articles/PMC2950264/
https://europepmc.org/articles/PMC2950264/
Autor:
Anna Lobell, Silvia Moretti, Johan Rönnelid, Fredrik Rorsman, Luigina Romani, Jaakko Perheentupa, Olle Kämpe, Hamish S. Scott, Brita Ardesjö Lundgren, P E Crewther, Sophie Bensing, Anna Norling, Kerstin M. Ahlgren, Jan Gustafsson, Åsa Hallgren, Erik Åhlin, Iulia Karlsson
Publikováno v:
European journal of immunology. 41(1)
usc Autoimmune polyendocrine syndrome type 1 (APS-1) is a multiorgan autoimmune disease caused by mutations in the autoimmune regulator (AIRE) gene. Chronic mucocutaneous candidiasis, hypoparathyroidism and adrenal failure are hallmarks of the diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84cc9f41a51579ffa71b240e1f300ec
https://pubmed.ncbi.nlm.nih.gov/21182094
https://pubmed.ncbi.nlm.nih.gov/21182094
Autor:
Hamish S. Scott, P E Crewther, William R. Heath, Anna I. Proeitto, Kylie E. Webster, Ping Cannon, Li Wu, Sarah Kinkel, François-Xavier Hubert
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(6)
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy is an autoimmune disorder caused by mutations in the autoimmune regulator gene AIRE. We examined the expression of Aire in different organs (thymus, spleen, and lymph nodes) in C57BL/6 mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d9e13b3a3c7aaee9d9662f0265dc7e
https://pubmed.ncbi.nlm.nih.gov/18322189
https://pubmed.ncbi.nlm.nih.gov/18322189