Zobrazeno 1 - 10
of 413
pro vyhledávání: '"P D Mitchell"'
Autor:
James M. Fulcher, Lye Meng Markillie, Hugh D. Mitchell, Sarah M. Williams, Kristin M. Engbrecht, David J. Degnan, Lisa M. Bramer, Ronald J. Moore, William B. Chrisler, Joshua Cantlon-Bruce, Johannes W. Bagnoli, Wei-Jun Qian, Anjali Seth, Ljiljana Paša-Tolić, Ying Zhu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Single-cell multiomics provides comprehensive insights into gene regulatory networks, cellular diversity, and temporal dynamics. Here, we introduce nanoSPLITS (nanodroplet SPlitting for Linked-multimodal Investigations of Trace Samples), an
Externí odkaz:
https://doaj.org/article/fabf8672d06842f19158f7743790121d
Autor:
Matthew Lui, Noah Kim, Raja Zaghlol, Pouya Joolharzadeh, Elena Deych, Clifford Robinson, Shahed Badiyan, Pamela K. Woodard, Joshua D. Mitchell
Publikováno v:
Cardio-Oncology, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Background Patients with non-small cell lung cancer (NSCLC) undergoing thoracic radiation are at high cardiovascular risk. Semiquantitative assessment of coronary artery calcification (CAC) on baseline planning non-gated chest computed tomog
Externí odkaz:
https://doaj.org/article/c9b03ae6351b4939b1327d83093fb84c
Publikováno v:
Algorithms for Molecular Biology, Vol 19, Iss 1, Pp 1-27 (2024)
Abstract The tree of blobs of a species network shows only the tree-like aspects of relationships of taxa on a network, omitting information on network substructures where hybridization or other types of lateral transfer of genetic information occur.
Externí odkaz:
https://doaj.org/article/cbe719d991894c18bf1ce68c503d7194
Autor:
Ghislain Rocheleau, Shoa L. Clarke, Gaëlle Auguste, Natalie R. Hasbani, Alanna C. Morrison, Adam S. Heath, Lawrence F. Bielak, Kruthika R. Iyer, Erica P. Young, Nathan O. Stitziel, Goo Jun, Cecelia Laurie, Jai G. Broome, Alyna T. Khan, Donna K. Arnett, Lewis C. Becker, Joshua C. Bis, Eric Boerwinkle, Donald W. Bowden, April P. Carson, Patrick T. Ellinor, Myriam Fornage, Nora Franceschini, Barry I. Freedman, Nancy L. Heard-Costa, Lifang Hou, Yii-Der Ida Chen, Eimear E. Kenny, Charles Kooperberg, Brian G. Kral, Ruth J. F. Loos, Sharon M. Lutz, JoAnn E. Manson, Lisa W. Martin, Braxton D. Mitchell, Rami Nassir, Nicholette D. Palmer, Wendy S. Post, Michael H. Preuss, Bruce M. Psaty, Laura M. Raffield, Elizabeth A. Regan, Stephen S. Rich, Jennifer A. Smith, Kent D. Taylor, Lisa R. Yanek, Kendra A. Young, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Austin T. Hilliard, Catherine Tcheandjieu, Patricia A. Peyser, Ramachandran S. Vasan, Jerome I. Rotter, Clint L. Miller, Themistocles L. Assimes, Paul S. de Vries, Ron Do
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Whole genome sequences (WGS) enable discovery of rare variants which may contribute to missing heritability of coronary artery disease (CAD). To measure their contribution, we apply the GREML-LDMS-I approach to WGS of 4949 cases and 17,494 c
Externí odkaz:
https://doaj.org/article/06f5575dd28f4c74ac4e7a972d07a02f
Autor:
Ran Yan, Zhaohua Dai, Daniel G. Shlian, Trinit'y D. Mitchell, Aaron Loo, Kaltrina Mulosmani, Rita K. Upmacis
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 80, Iss 10, Pp 1006-1009 (2024)
Coordination compounds of polydentate nitrogen ligands with metals are used extensively in research areas such as catalysis, and as models of complex active sites of enzymes in bioinorganic chemistry. Tris(2-pyridylmethyl)amine (TPA) is a tripodal te
Externí odkaz:
https://doaj.org/article/55829308ef6d44be99ad811c72452a80
Autor:
Gareth Hawkes, Robin N. Beaumont, Zilin Li, Ravi Mandla, Xihao Li, Christine M. Albert, Donna K. Arnett, Allison E. Ashley-Koch, Aneel A. Ashrani, Kathleen C. Barnes, Eric Boerwinkle, Jennifer A. Brody, April P. Carson, Nathalie Chami, Yii-Der Ida Chen, Mina K. Chung, Joanne E. Curran, Dawood Darbar, Patrick T. Ellinor, Myrian Fornage, Victor R. Gordeuk, Xiuqing Guo, Jiang He, Chii-Min Hwu, Rita R. Kalyani, Robert Kaplan, Sharon L. R. Kardia, Charles Kooperberg, Ruth J. F. Loos, Steven A. Lubitz, Ryan L. Minster, Take Naseri, Satupa’itea Viali, Braxton D. Mitchell, Joanne M. Murabito, Nicholette D. Palmer, Bruce M. Psaty, Susan Redline, M. Benjamin Shoemaker, Edwin K. Silverman, Marilyn J. Telen, Scott T. Weiss, Lisa R. Yanek, Hufeng Zhou, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Ching-Ti Liu, Kari E. North, Anne E. Justice, Jonathan M. Locke, Nick Owens, Anna Murray, Kashyap Patel, Timothy M. Frayling, Caroline F. Wright, Andrew R. Wood, Xihong Lin, Alisa Manning, Michael N. Weedon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The role of rare non-coding variation in complex human phenotypes is still largely unknown. To elucidate the impact of rare variants in regulatory elements, we performed a whole-genome sequencing association analysis for height using 333,100
Externí odkaz:
https://doaj.org/article/b2e3a91ecb614324b7f2fdd7370d5155
Autor:
Joshua P. Lewis, Kathleen A. Ryan, Elizabeth A. Streeten, Hilary B. Whitlatch, Melanie Daue, Keith Tanner, James A. Perry, Jeffrey R. O'Connell, Alan R. Shuldiner, Braxton D. Mitchell
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 11, Pp n/a-n/a (2024)
Abstract Antiplatelet therapy with a P2Y12 receptor inhibitor, in combination with aspirin, is standard of care for medical management of patients with coronary artery disease, and flexibility in prescribing options among these medications offers gre
Externí odkaz:
https://doaj.org/article/f0d43cfe0e25404a84926e644c4cd53b
Autor:
Sarah Y. Park, MD, Elizabeth Bashian, MD, Navin Vigneshwar, MD, Elizabeth A. David, MD, MAS, Simran K. Randhawa, MBBS, Robert A. Meguid, MD, MPH, John D. Mitchell, MD, Alice L. Gray, MD, Susana Arrigain, MA, Elizabeth A. Pomfret, MD, PhD, Jesse D. Schold, PhD, Michael T. Cain, MD, Jordan R.H. Hoffman, MD, MPH
Publikováno v:
JHLT Open, Vol 6, Iss , Pp 100148- (2024)
Background: To evaluate the association of right vs left single lung transplants (SLT) from split lung donors with long-term post-transplant recipient outcomes. Methods: We performed a retrospective review of the Scientific Registry of Transplant Rec
Externí odkaz:
https://doaj.org/article/212b135a79a246b891178c4769c77e2a
Autor:
Nimesh Patel, Mohamed Fayed, Wissam Maroun, Hannah Milad, Katie Adlaka, Lonnie Schultz, Rohit Aiyer, Patrick Forrest, John D. Mitchell
Publikováno v:
Annals of Cardiac Anaesthesia, Vol 27, Iss 3, Pp 193-201 (2024)
With the advancements in regional anesthesia and ultrasound techniques, the use of non-neuraxial blocks like the erector spinae plane block (ESPB) has been increasing in cardiac surgeries with promising outcomes. A total of 3,264 articles were identi
Externí odkaz:
https://doaj.org/article/8703286ef456491693c210e97c05f745
Autor:
Jacob L. Johansen, Matthew D. Mitchell, Grace O. Vaughan, Daniel M. Ripley, Holly A. Shiels, John A. Burt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The impact of ocean warming on fish and fisheries is vigorously debated. Leading theories project limited adaptive capacity of tropical fishes and 14-39% size reductions by 2050 due to mass-scaling limitations of oxygen supply in larger indi
Externí odkaz:
https://doaj.org/article/904c8833d03f40c7a8116361d087ed34