Zobrazeno 1 - 10
of 13
pro vyhledávání: '"P D, Soloway"'
Autor:
Seoyeon Lee, Abigail M. Benvie, Hui Gyu Park, Roman Spektor, Blaine Harlan, J. Thomas Brenna, Daniel C. Berry, Paul D. Soloway
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Adipocyte beiging is a thermogenic response to cold exposure and b3-adrenergic receptor agonists, which exert their effects by distinct and common molecular mechanisms that control chromatin accessibility and lipid metabolism.
Externí odkaz:
https://doaj.org/article/9ecacc2372344959befed191d75666c6
Autor:
Blaine Harlan, Hui Gyu Park, Roman Spektor, Bethany Cummings, J. Thomas Brenna, Paul D. Soloway
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Obesity promotes type 2 diabetes and cardiometabolic pathologies. Vertical sleeve gastrectomy (VSG) is used to treat obesity resulting in long-term weight loss and health improvements that precede weight loss; however, the mechanisms underlying the i
Externí odkaz:
https://doaj.org/article/1b24acb0632749408fa78c5af55cd0ab
Autor:
Roger D. Soloway, Alexander T. Hewlett
Publikováno v:
Annals of Hepatology, Vol 6, Iss 4, Pp 204-207 (2007)
The treatment of autoimmune hepatitis is evolving as the natural history of the disease and newer agents become available. This concise review will outline the various treatment options in these patients. Treatment with current corticosteroids and az
Externí odkaz:
https://doaj.org/article/35c12f60a1bb42d78faee36e7ae991d3
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53880 (2013)
Chromatin is separated into functional domains distinguished by combinatorial patterns of post-translational histone modifications and DNA methylation. Recent studies examining multiple histone modifications have found numerous chromatin states with
Externí odkaz:
https://doaj.org/article/95b01d909cf34744ad1483798dfcc3eb
Autor:
Yoon Jung Park, Herry Herman, Ying Gao, Anders M Lindroth, Benjamin Y Hu, Patrick J Murphy, James R Putnam, Paul D Soloway
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33024 (2012)
Epigenetic marks are fundamental to normal development, but little is known about signals that dictate their placement. Insights have been provided by studies of imprinted loci in mammals, where monoallelic expression is epigenetically controlled. Im
Externí odkaz:
https://doaj.org/article/9d7d8f8e9de248d7aacc9295b82457d1
Autor:
Huafeng Zou, Runsheng Li, Yimin Jia, Xiaojing Yang, Yingdong Ni, Rihua Cong, Paul D Soloway, Ruqian Zhao
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40432 (2012)
Glucocorticoids are vital for life and regulate an array of physiological functions by binding to the ubiquitously expressed glucocorticoid receptor (GR, also known as NR3C1). Previous studies demonstrate striking breed differences in plasma cortisol
Externí odkaz:
https://doaj.org/article/dfb17335e9a14123833e5aa8b839728f
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13784 (2010)
Rasgrf1 is imprinted in mouse, displaying paternal allele specific expression in neonatal brain. Paternal expression is accompanied by paternal-specific DNA methylation at a differentially methylated domain (DMD) within the locus. The cis-acting elem
Externí odkaz:
https://doaj.org/article/7ea56fd9068f40448faa29793eedaf00
Autor:
Anders M Lindroth, Yoon Jung Park, Chelsea M McLean, Gregoriy A Dokshin, Jenna M Persson, Herry Herman, Diego Pasini, Xavier Miró, Mary E Donohoe, Jeannie T Lee, Kristian Helin, Paul D Soloway
Publikováno v:
PLoS Genetics, Vol 4, Iss 8, p e1000145 (2008)
At the imprinted Rasgrf1 locus in mouse, a cis-acting sequence controls DNA methylation at a differentially methylated domain (DMD). While characterizing epigenetic marks over the DMD, we observed that DNA and H3K27 trimethylation are mutually exclus
Externí odkaz:
https://doaj.org/article/e299bc2a2fe44ace9ba9e3df4e48d32b
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3839 (2008)
Imprinted genes display differential allelic expression in a manner that depends on the sex of the transmitting parent. The degree of imprinting is often tissue-specific and/or developmental stage-specific, and may be altered in some diseases includi
Externí odkaz:
https://doaj.org/article/5876a12a29d64617ad0d654fd41afc4e
Publikováno v:
The Journal of Immunology. 147:3296-3302
In a murine model of T cell-mediated autoimmune disease, experimental autoimmune encephalitis (EAE), 80% of all encephalitogenic T cell clones in H-2u mice use the V beta 8.2 TCR element. To induce EAE in susceptible strains of mice either heat-kille
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecd2ae49dfe297797b395af8d3df6331
https://doi.org/10.4049/jimmunol.147.10.3296
https://doi.org/10.4049/jimmunol.147.10.3296