Zobrazeno 1 - 9
of 9
pro vyhledávání: '"P D, Soldato"'
Autor:
D. Soldato, L. Arecco, E. Agostinetto, M. A. Franzoi, E. Mariamidze, S. Begijanashvili, N. Brunetti, S. Spinaci, C. Solinas, I. Vaz-Luis, A. Di Meglio, M. Lambertini
Publikováno v:
Oncology and Therapy, Vol 11, Iss 2, Pp 199-229 (2023)
Abstract Prevalence of survivors of breast cancer has been steadily increasing in the last 20 years. Currently, more than 90% of women diagnosed with early-stage breast cancer are expected to be alive at 5 years from diagnosis thanks to early detecti
Externí odkaz:
https://doaj.org/article/443a2186891f4498a419d91e113e3d30
Autor:
S, Fiorucci, L, Santucci, B, Federici, E, Antonelli, E, Distrutti, O, Morelli, G D, Renzo, G, Coata, G, Cirino, P D, Soldato, A, Morelli
Nitric oxide (NO)-releasing NSAIDs are a new class of NSAID derivatives with markedly reduced gastrointestinal toxicity. Although it has been demonstrated that NO-NSAIDs spare gastric mucosal blood flow, molecular determinants involved in this effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::198c1368112b8a96b56c80bbd054f6e4
http://hdl.handle.net/11391/151827
http://hdl.handle.net/11391/151827
Autor:
Angela Ianaro, L. Lippolis, Giuseppe Cirino, Piero Del Soldato, Pasquale Maffia, Maiello Fm, Raffella Sorrentino, Armando Ialenti
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 22:263-267
One of the major problems related to the percutaneous transluminal coronary angioplasty technique is the renarrowing of the vessel, a phenomenon known as restenosis. NO and nonsteroidal anti-inflammatory drugs have been shown to play a role in this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af77397b27b41a70f319797f4b7d941
https://doi.org/10.1161/hq0202.104064
https://doi.org/10.1161/hq0202.104064
Publikováno v:
Expert Opinion on Investigational Drugs. 6:533-538
Long-term use of aspirin as an antithrombotic agent is limited by its toxicity in the gastrointestinal tract. Even very low doses of aspirin can markedly increase the risk of gastrointestinal bleeding and ulceration. Addition of a nitric oxide (NO)-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7806f30a3a148337ffad7d602885bf31
https://doi.org/10.1517/13543784.6.5.533
https://doi.org/10.1517/13543784.6.5.533
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
Aspirin is increasingly being used for long-term prophylaxis of myocardial infarction and stroke, but its use is limited by toxicity in the gastrointestinal tract. Even very low doses of aspirin can markedly increase the risk of gastrointestinal blee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4fe4600494dfe19cd6a3387c50863756
https://pubmed.ncbi.nlm.nih.gov/16158351
https://pubmed.ncbi.nlm.nih.gov/16158351
Autor:
Giuseppe Cirino, Piero Del Soldato, Antonio Morelli, Stefano Fiorucci, Luca Santucci, Luigi Familiari, Andrea Mencarelli
Publikováno v:
Scopus-Elsevier
Caspase-1, the IL-1β converting enzyme (ICE), is required for intracellular processing/maturation of IL-1β and IL-18. NO releasing nonsteroidal antiinflammatory drugs (NSAIDs) are a new class of NSAID derivatives that spare the gastric mucosa. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785b09034cb82b4a45e84d113466369c
http://hdl.handle.net/11588/469965
http://hdl.handle.net/11588/469965
Autor:
Michael Dicay, Giuseppe Cirino, Piero Del Soldato, John L. Wallace, Marcelo Nicolas Muscará, Webb McKnight
In summary, these results demonstrate that NCX-4016 can inhibit thrombus formation in an in vivo model. This effect is most likely due to nitric oxide release from the compound, but may also be dependent, to some extent, on suppression of thromboxane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bae413bb495dc725e4289b4ba386547
http://hdl.handle.net/11588/468558
http://hdl.handle.net/11588/468558
Publikováno v:
Scopus-Elsevier
Effects of a nitroxybutylester derivative of aspirin (NCX 4215) on platelet aggregation and prostanoid synthesis were compared to the effects of aspirin. NCX 4215 was approximately seven times more potent than aspirin as an inhibitor of thrombin-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fd4d09f029152b7ccdfea9f3ca65e4
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028800359&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028800359&partnerID=MN8TOARS
Autor:
Anwar R. Baydoun, P. Del Soldato, Caroline P.D. Wheeler-Jones, John L. Wallace, Giuseppe Cirino
Publikováno v:
Scopus-Elsevier
1. The effects of novel nitric oxide-releasing nonsteroidal anti-inflammatory compounds (NO-NSAIDs) on induction of nitric oxide (NO) synthase by bacterial lipopolysaccharide (LPS) were examined in a murine cultured macrophage cell line, J774. 2. LPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbe829644349351d8ef338545d46369
http://www.scopus.com/inward/record.url?eid=2-s2.0-0029979472&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0029979472&partnerID=MN8TOARS