Zobrazeno 1 - 10
of 13
pro vyhledávání: '"P D, Kingsley"'
Autor:
Nazish N. Jeffery, Christina Davidson, Scott A. Peslak, Paul D. Kingsley, Yukio Nakamura, James Palis, Michael Bulger
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-15 (2021)
Abstract Background Condensation of chromatin prior to enucleation is an essential component of terminal erythroid maturation, and defects in this process are associated with inefficient erythropoiesis and anemia. However, the mechanisms involved in
Externí odkaz:
https://doaj.org/article/49df9d0502544e9f8af90c63844d0d03
Autor:
Sierra Fox, Jacquelyn A. Myers, Christina Davidson, Michael Getman, Paul D. Kingsley, Nicholas Frankiewicz, Michael Bulger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Super-enhancer are usually defined by high levels of chromatin modification and associate with cell-specific gene expression. Here, the authors define hyperacetylated chromatin domains (HCDs) by using histone hyperacetylation peak breadth information
Externí odkaz:
https://doaj.org/article/ee98d3c56057456481faaea3dd0b0a5f
Autor:
Yu-Shan Huang, Luis F. Delgadillo, Kathryn H. Cyr, Paul D. Kingsley, Xiuli An, Kathleen E. McGrath, Narla Mohandas, John G. Conboy, Richard E. Waugh, Jiandi Wan, James Palis
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Hematopoietic ontogeny is characterized by distinct primitive and definitive erythroid lineages. Definitive erythroblasts mature and enucleate extravascularly and form a unique membrane skeleton, composed of spectrin, 4.1R-complex, and ankyr
Externí odkaz:
https://doaj.org/article/59ae1bf1686e4ba7bff3a96a98431c78
Autor:
Ah Ram Kim, Jayme L. Olsen, Samantha J. England, Yu-Shan Huang, Katherine H. Fegan, Luis F. Delgadillo, Kathleen E. McGrath, Paul D. Kingsley, Richard E. Waugh, James Palis
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 995-1003 (2015)
Red blood cells (RBCs), responsible for oxygen delivery and carbon dioxide exchange, are essential for our well-being. Alternative RBC sources are needed to meet the increased demand for RBC transfusions projected to occur as our population ages. We
Externí odkaz:
https://doaj.org/article/3ae0fc0361fe4cda8fa7712907e42bec
Autor:
Kathleen E. McGrath, Jenna M. Frame, Katherine H. Fegan, James R. Bowen, Simon J. Conway, Seana C. Catherman, Paul D. Kingsley, Anne D. Koniski, James Palis
Publikováno v:
Cell Reports, Vol 11, Iss 12, Pp 1892-1904 (2015)
Hematopoietic potential arises in mammalian embryos before adult-repopulating hematopoietic stem cells (HSCs). At embryonic day 9.5 (E9.5), we show the first murine definitive erythro-myeloid progenitors (EMPs) have an immunophenotype distinct from p
Externí odkaz:
https://doaj.org/article/269ef6228cb94fd289fb02d1e72d7407
Autor:
Zanhua Yi, Orit Cohen-Barak, Nobuko Hagiwara, Paul D Kingsley, Deborah A Fuchs, Drew T Erickson, Elliot M Epner, James Palis, Murray H Brilliant
Publikováno v:
PLoS Genetics, Vol 2, Iss 2, p e14 (2006)
Sox6 is a member of the Sox transcription factor family that is defined by the conserved high mobility group (HMG) DNA binding domain, first described in the testis determining gene, Sry. Previous studies have suggested that Sox6 plays a role in the
Externí odkaz:
https://doaj.org/article/9e9fdcae6e744fdc95c8c038d916c151
Autor:
David G Ransom, Nathan Bahary, Knut Niss, David Traver, Caroline Burns, Nikolaus S Trede, Noelle Paffett-Lugassy, Walter J Saganic, C Anthoney Lim, Candace Hersey, Yi Zhou, Bruce A Barut, Shuo Lin, Paul D Kingsley, James Palis, Stuart H Orkin, Leonard I Zon
Publikováno v:
PLoS Biology, Vol 2, Iss 8, p E237 (2004)
Hematopoiesis is precisely orchestrated by lineage-specific DNA-binding proteins that regulate transcription in concert with coactivators and corepressors. Mutations in the zebrafish moonshine (mon) gene specifically disrupt both embryonic and adult
Externí odkaz:
https://doaj.org/article/409d4c8fde6f4b679fcb4de597e44cca
Publikováno v:
Immunology. 93(2)
To study inherent properties of somatic hypermutation of human immunoglobulin genes in the absence of antigen selection, mutations of human non-productive VH6 rearrangements enriched by subtractive hybridization were characterized. Ten unique clones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b18df414290786fc25cb917e8f9e1cf
https://pubmed.ncbi.nlm.nih.gov/9616365
https://pubmed.ncbi.nlm.nih.gov/9616365
Publikováno v:
Molecular reproduction and development. 49(4)
Extracellular glutathione peroxidase (EGPx) is a secreted selenium-dependent enzyme that reduces hydroperoxides and organic hydroperoxides. Selenium deficiency in females is associated with infertility and spontaneous abortion, suggesting a role for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d44c3cf29d1a12275d0a1a64e78c03a9
https://pubmed.ncbi.nlm.nih.gov/9508085
https://pubmed.ncbi.nlm.nih.gov/9508085
Autor:
W. L. CArroll, S. Perkings, V. Marder, P. D. Kingsley, T. Odrljin, N. B. Lenrner, C. Francis, F. Constantini, C. S. Bruggets, L. A. Spom
Publikováno v:
Journal of Pediatric Hematology/Oncology. 20:396
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bda372aa851a1f3f1ff3b88e5f990d21
https://doi.org/10.1097/00043426-199807000-00099
https://doi.org/10.1097/00043426-199807000-00099