Zobrazeno 1 - 10
of 48
pro vyhledávání: '"P C de Witt Hamer"'
Autor:
Ragnhild Holden Helland, Alexandros Ferles, André Pedersen, Ivar Kommers, Hilko Ardon, Frederik Barkhof, Lorenzo Bello, Mitchel S. Berger, Tora Dunås, Marco Conti Nibali, Julia Furtner, Shawn Hervey-Jumper, Albert J. S. Idema, Barbara Kiesel, Rishi Nandoe Tewari, Emmanuel Mandonnet, Domenique M. J. Müller, Pierre A. Robe, Marco Rossi, Lisa M. Sagberg, Tommaso Sciortino, Tom Aalders, Michiel Wagemakers, Georg Widhalm, Marnix G. Witte, Aeilko H. Zwinderman, Paulina L. Majewska, Asgeir S. Jakola, Ole Solheim, Philip C. De Witt Hamer, Ingerid Reinertsen, Roelant S. Eijgelaar, David Bouget
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Extent of resection after surgery is one of the main prognostic factors for patients diagnosed with glioblastoma. To achieve this, accurate segmentation and classification of residual tumor from post-operative MR images is essential. The cur
Externí odkaz:
https://doaj.org/article/5ace2b3864664c65b8a85486587c3677
Autor:
Stan L. W. Driessens, Anna A. Galakhova, Djai B. Heyer, Isabel J. Pieterse, René Wilbers, Eline J. Mertens, Femke Waleboer, Tim S. Heistek, Loet Coenen, Julia R. Meijer, Sander Idema, Philip C. de Witt Hamer, David P. Noske, Christiaan P. J. de Kock, Brian R. Lee, Kimberly Smith, Jonathan T. Ting, Ed S. Lein, Huibert D. Mansvelder, Natalia A. Goriounova
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract GWAS have identified numerous genes associated with human cognition but their cell type expression profiles in the human brain are unknown. These genes overlap with human accelerated regions (HARs) implicated in human brain evolution and mig
Externí odkaz:
https://doaj.org/article/50832097a77b45fca91162348467e082
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Management of gliomas requires an invasive treatment strategy, including extensive surgical resection. The objective of the neurosurgeon is to maximize tumor removal while preserving healthy brain tissue. However, the lack of a clear tumor b
Externí odkaz:
https://doaj.org/article/7b71a467e6664dccaccf2f4b7a3dc632
Autor:
Caterina Brighi, Niels Verburg, Eng-Siew Koh, Amy Walker, Cathy Chen, Sugendran Pillay, Philip C. de Witt Hamer, Farhannah Aly, Lois C. Holloway, Paul J. Keall, David E.J. Waddington
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 23, Iss , Pp 8-15 (2022)
Background and purpose: Glioblastoma (GBM) patients have a dismal prognosis. Tumours typically recur within months of surgical resection and post-operative chemoradiation. Multiparametric magnetic resonance imaging (mpMRI) biomarkers promise to impro
Externí odkaz:
https://doaj.org/article/ccc04573c6b34bc88475161dde74b6eb
Autor:
Jantine Geertruida Röttgering, Linda Douw, Philip C. de Witt Hamer, Mathilde C. M. Kouwenhoven, Tom Würdinger, Peter M. van de Ven, Louise Sharpe, Hans Knoop, Martin Klein
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Fatigue is the most frequent and burdensome symptom of patients with diffuse glioma. It is closely linked to decreased health-related quality of life and symptoms such as depression and sleep disturbances. Currently, there is no e
Externí odkaz:
https://doaj.org/article/fb949537545d4a8d98dad2f2cd555020
Autor:
Jantine G. Röttgering, Vera Belgers, Mathilde C.M. Kouwenhoven, Maaike Schuur, Tjeerd J. Postma, Claudia M. Nijboer, Myra E. van Linde, Philip C. de Witt Hamer, Linda Douw, Martin Klein
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e13278- (2023)
Background & aims: Glioma patients experience a multitude of symptoms that negatively affect their health-related quality of life. Symptoms vary greatly across disease phases, and the patients' stable phase might be particularly suitable for assessin
Externí odkaz:
https://doaj.org/article/fcc9aa3edf7a4b508cf2bf92ddf4817d
Autor:
T. Numan, S. D. Kulik, B. Moraal, J. C. Reijneveld, C. J. Stam, P. C. de Witt Hamer, J. Derks, A. M. E. Bruynzeel, M. E. van Linde, P. Wesseling, M. C. M. Kouwenhoven, M. Klein, T. Würdinger, F. Barkhof, J. J. G. Geurts, A. Hillebrand, L. Douw
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Non-invasively measured brain activity is related to progression-free survival in glioma patients, suggesting its potential as a marker of glioma progression. We therefore assessed the relationship between brain activity and increasing tumor
Externí odkaz:
https://doaj.org/article/db7a744192a044f1a2cdce3407df8c2d
Autor:
David Bouget, André Pedersen, Asgeir S. Jakola, Vasileios Kavouridis, Kyrre E. Emblem, Roelant S. Eijgelaar, Ivar Kommers, Hilko Ardon, Frederik Barkhof, Lorenzo Bello, Mitchel S. Berger, Marco Conti Nibali, Julia Furtner, Shawn Hervey-Jumper, Albert J. S. Idema, Barbara Kiesel, Alfred Kloet, Emmanuel Mandonnet, Domenique M. J. Müller, Pierre A. Robe, Marco Rossi, Tommaso Sciortino, Wimar A. Van den Brink, Michiel Wagemakers, Georg Widhalm, Marnix G. Witte, Aeilko H. Zwinderman, Philip C. De Witt Hamer, Ole Solheim, Ingerid Reinertsen
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
For patients suffering from brain tumor, prognosis estimation and treatment decisions are made by a multidisciplinary team based on a set of preoperative MR scans. Currently, the lack of standardized and automatic methods for tumor detection and gene
Externí odkaz:
https://doaj.org/article/981e52963d18429e965bf6f6e6793861
Autor:
Niels Verburg, Thomas Koopman, Maqsood Yaqub, Otto S. Hoekstra, Adriaan A. Lammertsma, Lothar A. Schwarte, Frederik Barkhof, Petra J. W. Pouwels, Jan J. Heimans, Jaap C. Reijneveld, Annemieke J. M. Rozemuller, William P. Vandertop, Pieter Wesseling, Ronald Boellaard, Philip C. de Witt Hamer
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract Background Positron emission tomography (PET) is increasingly used to guide local treatment in glioma. The purpose of this study was a direct comparison of two potential tracers for detecting glioma infiltration, O-(2-[18F]-fluoroethyl)-l-ty
Externí odkaz:
https://doaj.org/article/6d9c6a5bb9024f70a10e92b69f8c0b8e
Autor:
Nik Sol, Sjors G.J.G. in ‘t Veld, Adrienne Vancura, Maud Tjerkstra, Cyra Leurs, François Rustenburg, Pepijn Schellen, Heleen Verschueren, Edward Post, Kenn Zwaan, Jip Ramaker, Laurine E. Wedekind, Jihane Tannous, Bauke Ylstra, Joep Killestein, Farrah Mateen, Sander Idema, Philip C. de Witt Hamer, Anna C. Navis, William P.J. Leenders, Ann Hoeben, Bastiaan Moraal, David P. Noske, W. Peter Vandertop, R. Jonas A. Nilsson, Bakhos A. Tannous, Pieter Wesseling, Jaap C. Reijneveld, Myron G. Best, Thomas Wurdinger
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101- (2020)
Summary: Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA pro
Externí odkaz:
https://doaj.org/article/3c63ceb85e20460e8535824c45ce6bd6