Zobrazeno 1 - 10
of 136
pro vyhledávání: '"P C Hindmarsh"'
Autor:
Sze May Ng, Neil P. Wright, Diana Yardley, Fiona Campbell, Tabitha Randell, Nicola Trevelyan, Atrayee Ghatak, Peter C. Hindmarsh
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-8 (2024)
Abstract Hybrid closed-loop (HCL) systems seamlessly interface continuous glucose monitoring (CGM) with insulin pumps, employing specialised algorithms and user-initiated automated insulin delivery. This study aimed to assess the efficacy of HCLs at
Externí odkaz:
https://doaj.org/article/1aad935d437a4974803c6bdcdb6e2a21
Autor:
Peter C Hindmarsh, John W Honour
Publikováno v:
International Journal of Endocrinology, Vol 2020 (2020)
There is an increase in mortality and morbidity as well as poor quality of life in patients with congenital adrenal hyperplasia (CAH) and other causes of adrenal insufficiency. Glucocorticoid replacement therapy should aim to replace the missing cort
Externí odkaz:
https://doaj.org/article/6a66157d4df84e4387329a127c3d048c
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199635 (2018)
ObjectivesC-peptide (CP) loss in type 1 diabetes (T1D) is highly variable, and factors influencing it are poorly understood. We modelled CP values in T1D patients from diagnosis for up to 6 years, treating the serial data as growth curves plotted aga
Externí odkaz:
https://doaj.org/article/8c901b0cb06c4b53937e73055519285e
Akademický článek
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Autor:
P C Hindmarsh, Tom R. Kurzawinski, W van't Hoff, M.T. Dattani, Caroline Brain, S. Alagaratnam, Helen Spoudeas, J. Allgrove
Publikováno v:
Journal of Pediatric Surgery. 49:1539-1543
Background Hyperparathyroidism (HPT) in children is rare and surgical management is supported only by limited evidence. Methods Retrospective case series of all children under the age of 16years who underwent parathyroidectomy (PTx) between 1978 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3483a6535f2a9f730f165f06da0aa6e9
https://doi.org/10.1016/j.jpedsurg.2014.05.032
https://doi.org/10.1016/j.jpedsurg.2014.05.032
Autor:
Cgd Brook, David R. Matthews, P. C. Hindmarsh, Evangelia Charmandari, Steven M. Pincus, Atholl Johnston
Publikováno v:
Scopus-Elsevier
In humans, growth hormone (GH) and cortisol are secreted in a pulsatile fashion and a mutual bidirectional interaction between the GH/insulin-like growth factor (IGF)-I axis and hypothalamic-pituitary-adrenal (HPA) axis has been established. Classic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6e9e1654331ec8e33de671e596a17c
https://doi.org/10.1515/jpem.2003.16.8.1119
https://doi.org/10.1515/jpem.2003.16.8.1119
A linear relation between fasting serum insulin concentration and height velocity was found in 47 normal children. This suggests that doubling of growth velocity at puberty is accompanied by a two to threefold rise in insulin. This implies that insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ebcfe2418c3f2ff66b2baeaa23024e
https://ora.ox.ac.uk/objects/uuid:9fda62c0-ed21-4937-b988-244807e3ccea
https://ora.ox.ac.uk/objects/uuid:9fda62c0-ed21-4937-b988-244807e3ccea
OBJECTIVE: To determine whether duration of exposure to GH and/or rate of change of serum GH concentration are important factors in determining the growth rate of short children. DESIGN: An analysis of parameters of occupancy percentage and rate of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57807fe6b42383b9de304038f72b44aa
https://doi.org/10.1111/j.1365-2265.1992.tb00952.x
https://doi.org/10.1111/j.1365-2265.1992.tb00952.x
Autor:
David R Matthews, Simon T. Meller, Diana Tait, M. Ryalls, H A Spoudeas, Cgd Brook, P. C. Hindmarsh
We studied 24-h hormone profiles and hormonal responses to insulin-induced hypoglycaemia prospectively in 23 children of similar age and pubertal stage, nine of whom had received prior cranial irradiation (group 1) and fourteen of whom had not (group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02177914cdcc0210e27c0b1cd2ab15a
https://ora.ox.ac.uk/objects/uuid:86524757-7f01-4167-9694-8803425e1256
https://ora.ox.ac.uk/objects/uuid:86524757-7f01-4167-9694-8803425e1256
SUMMARY A deconvolution analysis model to calculate pituitary growth hormone (GH) secretion rate from measured serum GH concentration has been developed. This uses an iterative method of‘curve-stripping’based on an estimate of the half-life. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9b4c0dcf422d6e7f8e51f36798f160
https://ora.ox.ac.uk/objects/uuid:7c872039-f9d6-4e67-a7bc-636637668f6b
https://ora.ox.ac.uk/objects/uuid:7c872039-f9d6-4e67-a7bc-636637668f6b