Zobrazeno 1 - 10
of 15
pro vyhledávání: '"P C, Moody"'
Autor:
Yohei Matsunaga, Hiroshi Qadota, Nasab Ghazal, Leila Lesanpezeshki, Till Dorendorf, Jasmine C. Moody, Arnaud Ahier, Courtney J. Matheny, Siva A. Vanapalli, Steven Zuryn, Olga Mayans, Jennifer Q. Kwong, Guy M. Benian
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract UNC-89 is a giant sarcomeric M-line protein required for sarcomere organization and optimal muscle function. UNC-89 contains two protein kinase domains, PK1 and PK2, separated by an elastic region. Here we show that PK2 is a canonical kinase
Externí odkaz:
https://doaj.org/article/bba44bd80c7247d28d8e36412ab42597
Autor:
Simon T. Bond, Emily J. King, Darren C. Henstridge, Adrian Tran, Sarah C. Moody, Christine Yang, Yingying Liu, Natalie A. Mellett, Artika P. Nath, Michael Inouye, Elizabeth J. Tarling, Thomas Q. de Aguiar Vallim, Peter J. Meikle, Anna C. Calkin, Brian G. Drew
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The genetic determinants of sex-specific differences in obesity are still incompletely understood. Here, the authors demonstrate that adipocyte specific loss of Trim28 in committed adipocytes leads to sex specific differences in the development of ob
Externí odkaz:
https://doaj.org/article/153ba01f3e9e4f4784fc02d6c030c7c9
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Activin A, a TGFβ superfamily member, is important for normal testis development through its actions on Sertoli cell development. Our analyses of altered activin A mouse models indicated gonocyte abnormalities, implicating activin A as a key determi
Externí odkaz:
https://doaj.org/article/1cca202fbcd24948b73ee09bf267d8a9
Autor:
Jasmine C. Moody, Hiroshi Qadota, April R. Reedy, C. Denise Okafor, Niveda Shanmugan, Yohei Matsunaga, Courtney J. Christian, Eric A. Ortlund, Guy M. Benian
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
PIX proteins activate the small GTPases Rac and Cdc42, and are known to have numerous functions in a variety of cell types. Using a genetic screen in C. elegans, the authors find that PIX-1 is required for the assembly or stability of integrin adhesi
Externí odkaz:
https://doaj.org/article/97b17489d39b4b8787aa01fe4c4441f9
Autor:
Aowen Zhuang, Anna C. Calkin, Shannen Lau, Helen Kiriazis, Daniel G. Donner, Yingying Liu, Simon T. Bond, Sarah C. Moody, Eleanor A.M. Gould, Timothy D. Colgan, Sergio Ruiz Carmona, Michael Inouye, Thomas Q. de Aguiar Vallim, Elizabeth J. Tarling, Gregory A. Quaife-Ryan, James E. Hudson, Enzo R. Porrello, Paul Gregorevic, Xiao-Ming Gao, Xiao-Jun Du, Julie R. McMullen, Brian G. Drew
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102537- (2021)
Summary: Long non-coding RNAs (lncRNAs) have been demonstrated to influence numerous biological processes, being strongly implicated in the maintenance and physiological function of various tissues including the heart. The lncRNA OIP5-AS1 (1700020I14
Externí odkaz:
https://doaj.org/article/453eb2947cf84c34a110e74e3feab67a
Autor:
Anna M. D. Watson, Eleanor A. M. Gould, Sarah C. Moody, Priyadharshini Sivakumaran, Karly C. Sourris, Bryna S. M. Chow, Audrey Koïtka-Weber, Terri J. Allen, Karin A. M. Jandeleit-Dahm, Mark E. Cooper, Anna C. Calkin
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
It is well established that diabetes is the major cause of chronic kidney disease worldwide. Both hyperglycemia, and more recently, advanced glycation endproducts, have been shown to play critical roles in the development of kidney disease. Moreover,
Externí odkaz:
https://doaj.org/article/73fcf4a9c4324f12af7fc95a222337db
Autor:
Emily C Moody, Elena Colicino, Robert O Wright, Ezekiel Mupere, Ericka G Jaramillo, Chitra Amarasiriwardena, Sarah E Cusick
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233108 (2020)
BackgroundStunting is an indicator of poor linear growth in children and is an important public health problem in many countries. Both nutritional deficits and toxic exposures can contribute to lower height-for-age Z-score (HAZ) and stunting (HAZ < -
Externí odkaz:
https://doaj.org/article/f079530e65d148c8b1d2a4786b5394ba
Autor:
Sarah E. Cusick, Ericka G. Jaramillo, Emily C. Moody, Andrew S. Ssemata, Doreen Bitwayi, Troy C. Lund, Ezekiel Mupere
Publikováno v:
BMC Public Health, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Exposure to environmental heavy metals is common among African children. Although many of these metals are known neurotoxicants, to date, monitoring of this exposure is limited, even in countries such as Uganda that are undergoing
Externí odkaz:
https://doaj.org/article/55fa1c0f15f5470ba4353e5263cd990c
Autor:
Mollika A. Sajady, Christopher J. Mehus, Emily C. Moody, Ericka G. Jaramillo, Ezekiel Mupere, Andrew J. Barnes, Sarah E. Cusick
Publikováno v:
Children, Vol 5, Iss 8, p 101 (2018)
There is a need for developmental screening that is easily administered in resource-poor settings. We hypothesized that known risk factors would predict failed developmental screening on an adapted screening tool in East African children living in po
Externí odkaz:
https://doaj.org/article/b3b1d590727d409da2d48cd963d56132
Publikováno v:
The Biochemical journal. 359(Pt 2)
The side chain of residue Arg(238) in morphinone reductase (MR) is located close to the N-1/C-2 carbonyl region of the flavin isoalloxazine ring. During enzyme reduction negative charge develops in this region of the flavin. The positioning of a posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1164beba37f014002ed6e30d165839d
https://pubmed.ncbi.nlm.nih.gov/11583577
https://pubmed.ncbi.nlm.nih.gov/11583577