Zobrazeno 1 - 10
of 35
pro vyhledávání: '"P C, Driscoll"'
Autor:
Leonard L. de Boer, Lesley Vanes, Serena Melgrati, Joshua Biggs O’May, Darryl Hayward, Paul C. Driscoll, Jason Day, Alexander Griffiths, Renata Magueta, Alexander Morrell, James I. MacRae, Robert Köchl, Victor L. J. Tybulewicz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Migration of T cells is essential for their ability to mount immune responses. Chemokine-induced T cell migration requires WNK1, a kinase that regulates ion influx into the cell. However, it is not known why ion entry is necessary for T cell
Externí odkaz:
https://doaj.org/article/756fb5c46001461296daa26e0aeb116f
Autor:
Marc Hennequart, Christiaan F. Labuschagne, Mylène Tajan, Steven E. Pilley, Eric C. Cheung, Nathalie M. Legrave, Paul C. Driscoll, Karen H. Vousden
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Cancer cells in culture are often grown in media conditions containing unphysiological metabolite levels. Here, the authors grow cells under physiological metabolite levels to further understand the reliance of cells on serine and find that when grow
Externí odkaz:
https://doaj.org/article/d92cf3d95d89487c9cc004996a158731
Autor:
Ratnasekhar Ch, Guillaume Rey, Sandipan Ray, Pawan K. Jha, Paul C. Driscoll, Mariana Silva Dos Santos, Dania M. Malik, Radoslaw Lach, Aalim M. Weljie, James I. MacRae, Utham K. Valekunja, Akhilesh B. Reddy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Red blood cells, which do not possess a nucleus, have circadian redox rhythms with incompletely understood regulatory mechanisms. Here the authors show that glucose metabolism plays a crucial role in regulating circadian redox status of human red blo
Externí odkaz:
https://doaj.org/article/5f02b6e3c1e54ddcb29ebb7ccce4706e
Autor:
Andrew H. Smith, MD, Priya Putta, PhD, Erin C. Driscoll, BS, Pinaki Chaudhuri, PhD, Lutz Birnbaumer, PhD, Michael A. Rosenbaum, MD, Linda M. Graham, MD
Publikováno v:
JVS - Vascular Science, Vol 1, Iss , Pp 136-150 (2020)
Objective: Previous studies showed the benefit of canonical transient receptor potential 6 (TRPC6) channel deficiency in promoting endothelial healing of arterial injuries in hypercholesterolemic animals. Long-term studies utilizing a carotid wire-in
Externí odkaz:
https://doaj.org/article/956f7e8de21d44cca17f7c2d0586f715
Publikováno v:
Biogeosciences, Vol 16, Pp 2189-2204 (2019)
Restoration of soils post-mining requires key solutions to complex issues through which the disturbance of topsoil incorporating soil microbial communities can result in a modification to ecosystem function. This research was in collaboration with Il
Externí odkaz:
https://doaj.org/article/8890f6af73e6432bb0953b1a5a95f43f
Autor:
M. Irina Stefana, Paul C. Driscoll, Fumiaki Obata, Ana Raquel Pengelly, Clare L. Newell, James I. MacRae, Alex P. Gould
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The diet consumed during development can have long-lasting effects on adult physiology. Here, the authors show that developmental undernutrition in Drosophila extends lifespan by inhibiting the production of toxic lipids, called autotoxins, on the ad
Externí odkaz:
https://doaj.org/article/49964fcd24ae4bed8845eb15473aa509
Autor:
Jamie A Macpherson, Alina Theisen, Laura Masino, Louise Fets, Paul C Driscoll, Vesela Encheva, Ambrosius P Snijders, Stephen R Martin, Jens Kleinjung, Perdita E Barran, Franca Fraternali, Dimitrios Anastasiou
Publikováno v:
eLife, Vol 8 (2019)
Several enzymes can simultaneously interact with multiple intracellular metabolites, however, how the allosteric effects of distinct ligands are integrated to coordinately control enzymatic activity remains poorly understood. We addressed this questi
Externí odkaz:
https://doaj.org/article/e58bac1bbbec4b70ba28e24697d45179
Publikováno v:
Water, Vol 13, Iss 3, p 264 (2021)
Microplastics have been documented in aquatic and terrestrial ecosystems throughout the world. However, few studies have investigated microplastics in freshwater fish diets. In this study, water samples and three trophic levels of a freshwater food w
Externí odkaz:
https://doaj.org/article/66701c8d42f44b289de197a03edef54d
Publikováno v:
Human-Wildlife Interactions, Vol 5, Iss 1 (2017)
The puaiohi or small Kauai thrush (Myadestes palmeri) is an endangered bird endemic to the island of Kauai, Hawaii. The sole population of about 500 birds is currently restricted to remote, higher elevation areas of the Alakai Plateau. Puaiohi nest p
Externí odkaz:
https://doaj.org/article/79a8b517f7d445daabbf65ab01cc3f1b
Autor:
F.R. Uwizeye, C. Driscoll, P.H. Park, V. Hategekimana, A. Umwizerwa, Denis Umuhizi, C.B. Smith, L. Shulman
Publikováno v:
Annals of Global Health, Vol 82, Iss 3 (2016)
Externí odkaz:
https://doaj.org/article/28bb19c4bb7f48a598e485142c39b918