Zobrazeno 1 - 10
of 137
pro vyhledávání: '"P Barton Duell"'
Autor:
Andrea DeBarber, Yaz Kisanuki, Paulo Nobrega, Ryan Himes, Suman Jayadev, John Bernat, Vikram Prakash, James Gibson, Austin Larson, Paulo Sgobbi, Edward Murphy, Brian Fedor, Cheryl Wong Po Foo, Rana Dutta, Michael Imperiale, Jolan Terner-Rosenthal, Will Garner, Pamela Vig, P. Barton Duell, Sarah Perez, Ritesh Ramdhani, Jonas Saute
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101039- (2024)
Externí odkaz:
https://doaj.org/article/42357f5775fb45ad9cbb1f099d5a0e41
Autor:
Dan Liang, Aleksei Mikhalchenko, Hong Ma, Nuria Marti Gutierrez, Tailai Chen, Yeonmi Lee, Sang-Wook Park, Rebecca Tippner-Hedges, Amy Koski, Hayley Darby, Ying Li, Crystal Van Dyken, Han Zhao, Keliang Wu, Jingye Zhang, Zhenzhen Hou, Seongjun So, Jongsuk Han, Jumi Park, Chong-Jai Kim, Kai Zong, Jianhui Gong, Yilin Yuan, Ying Gu, Yue Shen, Susan B. Olson, Hui Yang, David Battaglia, Thomas O’Leary, Sacha A. Krieg, David M. Lee, Diana H. Wu, P. Barton Duell, Sanjiv Kaul, Jin-Soo Kim, Stephen B. Heitner, Eunju Kang, Zi-Jiang Chen, Paula Amato, Shoukhrat Mitalipov
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
DNA repair in response to DSBs in the preimplantation embryo is hard to analyze. Here the authors show that over 25% of pre-existing heterozygous loci in control single blastomere samples appeared as homozygous after whole genome amplification, there
Externí odkaz:
https://doaj.org/article/ba06b7898e994b68a92e8beb9b442fb5
Autor:
Marina Cuchel, Paul C. Lee, Lisa C. Hudgins, P. Barton Duell, Zahid Ahmad, Seth J. Baum, MacRae F. Linton, Sarah D. de Ferranti, Christie M. Ballantyne, John A. Larry, Linda C. Hemphill, Iris Kindt, Samuel S. Gidding, Seth S. Martin, Patrick M. Moriarty, Paul P. Thompson, James A. Underberg, John R. Guyton, Rolf L. Andersen, David J. Whellan, Irwin Benuck, John P. Kane, Kelly Myers, William Howard, David Staszak, Allison Jamison, Mary C. Card, Mafalda Bourbon, Joana R. Chora, Daniel J. Rader, Joshua W. Knowles, Katherine Wilemon, Mary P. McGowan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 9 (2023)
Background Homozygous familial hypercholesterolemia (HoFH) is a rare, treatment‐resistant disorder characterized by early‐onset atherosclerotic and aortic valvular cardiovascular disease if left untreated. Contemporary information on HoFH in the
Externí odkaz:
https://doaj.org/article/9dcee4a6f1ed4758895b21e17b75e550
Autor:
Bruce A. Warden, PharmD, Tina Kaufman, PhD, PA-C, Jessica Minnier, PhD, P. Barton Duell, MD, Sergio Fazio, MD, PhD, Michael D. Shapiro, DO, MCR
Publikováno v:
JACC: Case Reports, Vol 2, Iss 3, Pp 396-399 (2020)
Standard lipid-lowering therapies in solid organ transplantations pose challenges due to interactions with immunosuppressants. Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) represent a new class of lipid-lowering therapies with po
Externí odkaz:
https://doaj.org/article/0c3eb702615d4759b5ee8c9cf52717d2
Autor:
Bruce A. Warden, Johannes Steiner, Albert Camacho, Khoa Nguyen, Jonathan Q Purnell, P. Barton Duell, Courtney Craigan, Diane Osborn, Sergio Fazio
Publikováno v:
American Journal of Preventive Cardiology, Vol 6, Iss , Pp 100183- (2021)
Heart failure with reduced ejection fraction (HFrEF) is a debilitating disease that is associated with substantial morbidity, mortality, and societal costs. The past three decades have brought about significant advancements in the pharmacologic manag
Externí odkaz:
https://doaj.org/article/fccf4e92be82469e9e8dba7de10a2e8d
Autor:
Jacqueline S. Dron, Jian Wang, Adam D. McIntyre, Henian Cao, John F. Robinson, P. Barton Duell, Priya Manjoo, James Feng, Irina Movsesyan, Mary J. Malloy, Clive R. Pullinger, John P. Kane, Robert A. Hegele
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 11, Pp 1953-1958 (2019)
Severe hypertriglyceridemia (HTG) is a relatively common form of dyslipidemia with a complex pathophysiology and serious health complications. HTG can develop in the presence of rare genetic factors disrupting genes involved in the triglyceride (TG)
Externí odkaz:
https://doaj.org/article/cdf329801bed4b7895839adade6cadb7
Autor:
Erik S.G. Stroes, Harold E. Bays, Maciej Banach, Alberico L. Catapano, P. Barton Duell, Ulrich Laufs, G.B. John Mancini, Kausik K. Ray, William J. Sasiela, Yang Zhang, Antonio M. Gotto
Publikováno v:
Atherosclerosis, 373, 1-9. Elsevier Ireland Ltd
Background and aims: High-sensitivity C-reactive protein (hsCRP), a marker for atherosclerotic cardiovascular disease risk, is reduced by bempedoic acid. We assessed the relationship between changes in low-density lipoprotein cholesterol (LDL-C) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054b1d8aa0f1ab6965a1b7fe7e7963c3
http://www.scopus.com/inward/record.url?scp=85151427440&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85151427440&partnerID=8YFLogxK
Autor:
Raman Puri, Vimal Mehta, P. Barton Duell, S.K. Wangnoo, Ashu Rastogi, V. Mohan, Abdul Hamid Zargar, Sanjay Kalra, Abhay Kumar Sahoo, S.S. Iyengar, Jamal Yusuf, Saibal Mukhopadhyay, Mani Kant Singla, Altamash Shaikh, Sunil Kohli, Sandeep Mathur, Sachin Jain, S.N. Narasingan, Vipul Gupta, Rajeev Agarwala, Vinod Mittal, Amit Varma, Jayant Kumar Panda, Sadanand Shetty, Madhur Yadav, A. Muruganathan, Pradeep Dabla, K.K. Pareek, P.C. Manoria, Rashmi Nanda, G.B. Sattur, A.K. Pancholia, Nathan D. Wong
Publikováno v:
Journal of Clinical Lipidology. 17:e1-e14
In 2021 an estimated 74 million individuals had diabetes in India, almost all type 2 diabetes. More than half of patients with diabetes are estimated to be undiagnosed and more 90% have dyslipidemia that is associated with accelerated development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc0df20602e0827681e7875ca477b38
https://doi.org/10.1016/j.jacl.2022.11.002
https://doi.org/10.1016/j.jacl.2022.11.002
Autor:
Bruce A. Warden, Jonathan Q. Purnell, P. Barton Duell, Courtney Craigan, Diane Osborn, Emily Cabot, Sergio Fazio
Publikováno v:
American Journal of Preventive Cardiology, Vol 5, Iss , Pp 100144- (2021)
Objective: To determine the real-world use of pharmacotherapy with new evidence-based cardiovascular indications in an academic Preventive Cardiology Clinic. Methods: A retrospective study of patients seen in our Center for Preventive Cardiology (CPC
Externí odkaz:
https://doaj.org/article/2393218ef725435ca60acce19886117b
Autor:
Philip Höflinger, Stefan Hauser, Eylan Yutuc, Holger Hengel, Lauren Griffiths, Florentine Radelfahr, Owain W. Howell, Yuqin Wang, Sonja L. Connor, P. Barton Duell, Andrea E. DeBarber, Peter Martus, Dieter Lütjohann, William J. Griffiths, Ludger Schöls
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100078- (2021)
Cerebrotendinous xanthomatosis (CTX) is caused by autosomal recessive loss-of-function mutations in CYP27A1, a gene encoding cytochrome p450 oxidase essential for bile acid synthesis, resulting in altered bile acid and lipid metabolism. Here, we aime
Externí odkaz:
https://doaj.org/article/41d7e6fd58f7466ca39ad0e0f6bfc8e4