Zobrazeno 1 - 10
of 1 091
pro vyhledávání: '"P B Mark"'
Autor:
Heather Walker, Scott Day, Christopher H. Grant, Catrin Jones, Robert Ker, Michael K. Sullivan, Bhautesh Dinesh Jani, Katie Gallacher, Patrick B. Mark
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Prognostic models that identify individuals with chronic kidney disease (CKD) at greatest risk of developing kidney failure help clinicians to make decisions and deliver precision medicine. It is recognised that people with CKD us
Externí odkaz:
https://doaj.org/article/0a894f732e6f446e9d15751df3dd6457
Autor:
Qiaoling Liu, Carlos Celis‐Morales, Jennifer S. Lees, Naveed Sattar, Frederick K. Ho, Jill P. Pell, Patrick B. Mark, Paul Welsh
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 2046-2055 (2024)
Abstract Background Previous research on the association between physical activity (PA) and kidney function is inconsistent. The association between muscle mass and serum creatinine (SCr) may have implications for interpreting the effect of PA on est
Externí odkaz:
https://doaj.org/article/e0366798ce734a9ba24d2bfcee032eea
Autor:
Benjamin M. P. Elyan, Michael K. Sullivan, James Hedley, Nicole De La Mata, Angela C. Webster, Balaji Venugopal, Rob J. Jones, Ninian N. Lang, Patrick B. Mark, Jennifer S. Lees
Publikováno v:
BJC Reports, Vol 2, Iss 1, Pp 1-9 (2024)
Abstract Background Drugs targeting angiogenesis and immunotherapy have transformed outcomes in renal cancer but may contribute to progressive kidney disease. Methods We linked healthcare databases in the West of Scotland (spanning 2010–2020) to id
Externí odkaz:
https://doaj.org/article/2e527c49e47e455da34385b545ad3f79
Autor:
Jaclyn Carberry, Mark C. Petrie, Matthew M.Y. Lee, Katriona Brooksbank, Ross T. Campbell, Richard Good, Pardeep S. Jhund, Peter Kellman, Ninian N. Lang, Kenneth Mangion, Patrick B. Mark, Alex McConnachie, John J.V. McMurray, Barbara Meyer, Vanessa Orchard, Aadil Shaukat, Stuart Watkins, Paul Welsh, Naveed Sattar, Colin Berry, Kieran F. Docherty
Publikováno v:
ESC Heart Failure, Vol 11, Iss 4, Pp 2001-2012 (2024)
Abstract Aims Patients with a reduced left ventricular ejection fraction (LVEF) following an acute myocardial infarction (MI) are at risk of progressive adverse cardiac remodelling that can lead to the development of heart failure and death. The earl
Externí odkaz:
https://doaj.org/article/2392cabc2be74029819f96fb1ade1e0f
Autor:
Reuben W. Nowell, Fernando Rodriguez, Bette J. Hecox-Lea, David B. Mark Welch, Irina R. Arkhipova, Timothy G. Barraclough, Christopher G. Wilson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Coevolutionary antagonism generates relentless selection that can favour genetic exchange, including transfer of antibiotic synthesis and resistance genes among bacteria, and sexual recombination of disease resistance alleles in eukaryotes.
Externí odkaz:
https://doaj.org/article/6833dc29d42543c79caf03231869fb14
Publikováno v:
BMJ Open, Vol 14, Iss 10 (2024)
Introduction Clinical guidelines recommend the use of the kidney failure risk equation (KFRE) to guide the referral of individuals with chronic kidney disease (CKD) to secondary kidney care services. People living with CKD frequently experience multi
Externí odkaz:
https://doaj.org/article/d08d82ca2e594920bbbf00e49ebd96cb
Publikováno v:
Kidney Medicine, Vol 6, Iss 8, Pp 100851- (2024)
Originally developed for use in type 2 diabetes mellitus (T2DM), sodium–glucose co-transporter-2 (SGLT2) inhibitors demonstrated diverse cardiovascular- and kidney-protective effects in large outcome trials. Their subsequent approval as a treatment
Externí odkaz:
https://doaj.org/article/e4a5f473d4f8447c86f52c8b6ba447b9
Autor:
Glenn M. Chertow, Hiddo Lambers Heerspink, Patrick B. Mark, Jamie P. Dwyer, Michal Nowicki, David C. Wheeler, Ricardo Correa-Rotter, Peter Rossing, Robert D. Toto, Anna Maria Langkilde, Niels Jongs
Publikováno v:
Glomerular Diseases (2024)
Introduction Despite the provision of renin-angiotensin-aldosterone-system inhibitors and immunosuppressive therapies, membranous nephropathy often progresses to end-stage kidney disease (ESKD). The objective of this prespecified analysis was to asse
Externí odkaz:
https://doaj.org/article/f7c6397ab9254160bd340782cae6b634
Autor:
Andrew J. Morrow, Robert Sykes, Merna Saleh, Baryab Zahra, Alasdair MacIntosh, Anna Kamdar, Catherine Bagot, Hannah K. Bayes, Kevin G. Blyth, Heerajnarain Bulluck, David Carrick, Colin Church, David Corcoran, Iain Findlay, Vivienne B. Gibson, Lynsey Gillespie, Douglas Grieve, Pauline Hall Barrientos, Antonia Ho, Ninian N. Lang, David J. Lowe, Vera Lennie, Peter W. Macfarlane, Kaitlin J. Mayne, Patrick B. Mark, Alex McConnachie, Ross McGeoch, Sabrina Nordin, Alexander Payne, Alastair J. Rankin, Keith Robertson, Nicola Ryan, Giles Roditi, Naveed Sattar, David Stobo, Sarah Allwood-Spiers, Rhian M. Touyz, Gruschen Veldtman, Sarah Weeden, Robin Weir, Stuart Watkins, Paul Welsh, Kenneth Mangion, Colin Berry
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-7 (2024)
Abstract Background The associations between deprivation and illness trajectory after hospitalisation for coronavirus disease-19 (COVID-19) are uncertain. Methods A prospective, multicentre cohort study was conducted on post-COVID-19 patients, enroll
Externí odkaz:
https://doaj.org/article/89c230cc0e254b7bb87fb521b7db8438
Autor:
Courtney O. Kelson, Josiane Weber Tessmann, Mariah E. Geisen, Daheng He, Chi Wang, Tianyan Gao, B. Mark Evers, Yekaterina Y. Zaytseva
Publikováno v:
Cells, Vol 13, Iss 19, p 1663 (2024)
Dysregulated fatty acid metabolism is an attractive therapeutic target for colorectal cancer (CRC). We previously reported that fatty acid synthase (FASN), a key enzyme of de novo synthesis, promotes the initiation and progression of CRC. However, th
Externí odkaz:
https://doaj.org/article/11004680a9274313bbb5bd28353efcae